
Places to stay near Biosphere 2
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Top-rated vacation rentals near Biosphere 2
Guests agree: these stays are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Mountain Dreams - Cozy Cabin - Amazing Views
Nestled in the heart of the mountains, this dream cabin exudes warmth and comfort. As you step inside, a welcoming feel of relaxing comfort. The living room is the heart of the cabin. A plush sofa & a cozy rug invite you to sit down and relax after a day of outdoor fun. Step out on to the deck and smell the fresh mountain air overlooking stunning Mountain Views. Sip your morning coffee in one of the 3 seating areas on the deck. Enjoy grilling a propane barbecue awaits your grilling skills.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Villa Clemente Central 1br Resort Oasis UofA Dtwn
Welcome to Villa Clemente, your peaceful desert escape in the heart of Tucson! This stylish, resort-inspired 1-bedroom retreat is perfect for solo travelers, couples, or a trio seeking comfort and convenience. Whether you're here for a campus visit, golf weekend, hiking adventure, or a restful staycation, Villa Clemente offers everything you need to relax and recharge. 1BR w/ rain shower, full kitchen, coffee bar, grill, putting green, luxe touches, near UofA, Reid Park, golf & hiking trails.

Tranquil Bears Path Casita
This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Cozy Mountain Retreat w/ Hot Tub
Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

Tucson Mountain Retreat
Stunningly beautiful mountain and city views!!! Relax on the spacious patio or in the heated spa with a favorite beverage and enjoy the wildlife and views. This home is situated in the foothills of the majestic giant Saguaro-studded Tucson Mountains, with easy access to the Desert Museum, Old Tucson Studios, Gates Pass, Tucson Mountain Park and the Sweetwater Preserve with outstanding biking and hiking trails. Downtown Tucson, U. of Arizona, and 4 golf courses are within 7-10 miles.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Little House in the Desert
Tiny Home. Very private. Peaceful and quiet. Lots of land surrounding. Separate driveway And huge lot area. Dog Ok. NO CATS New, extremely comfortable Queen memory foam/gel mattress in the bedroom and brand new Queen memory foam mattress in the pull out couch. This is the perfect little HOuse in the Desert and brand new! We are available to you and very close in the main house on the other side of the property. The houses are separated by a large brick wall.

1BR Casita on 17 Scenic Foothills Acres #9
Retreat to this peaceful 1-bedroom casita in West Foothills, set on a picturesque 17-acre property. Enjoy a king bed, AC/heat, full kitchen with RO water, icemaker, microwave, stove/oven, 65" Roku TV with 220 channels, fast WiFi, in-unit washer/dryer, and game table. ~800 sq ft of comfort and charm. Just 2 miles up Ironwood Hill Dr from Silverbell Rd, 6 miles to UofA. Impeccably clean and inviting, perfect for a tranquil escape. AZ TPT Lic 21337578

Time Capsule in the Sonoran Desert
Vibrant space-age cabin on an 11-acre desert art sanctuary near Saguaro National Park, 35 mins from Tucson! Features WiFi, AC/heat, outdoor bathroom deck & eco-amenities. Sits 15 yards from Groovy Glamper. 🚫 NO PETS/ESAs (Service Animals welcome). Delicate art decor makes this space strictly UNSUITABLE for children/minors. ⚠️ IMPORTANT: Before booking, note that check-in is strictly in person and no later than 10:00 PM. No exceptions!
Popular amenities for vacation rentals near Biosphere 2
Condo rentals with wifi

Ventana Canyon Condo with Pool View

Tasteful, Modern Luxury. Great Location.

Luxury Ventana Canyon Condo+Pools+Sabino Canyon!

Sweet Sabino Canyon Suite

The Sunrise Suite, a luxury 1 bed condo

Catalina Foothills Getaway

Cozy studio UNIT 3, WHITE DOOR

Charming 2-Bedroom Skyline Condo with Pool
Family-friendly house rentals

Stunning 4BR in the Catalinas with Heated Pool!

Views-GameRoom-Comfy Beds-Pool-Hiking@Saguaro West

Private Hilltop Hacienda Getaway - 360* views

La Palmera- Foothills Mountian Views + Pool

Peaceful Home in Tucson

Historic 1920s farmhouse

Foothills Luxury Pickleball Basketball Pool & Spa

INDOOR Pool , AMAZING Views, Game Room, Gym & more
Apartment rentals with air conditioning

Your own private luxurious 2 bedroom getaway

Cat Mountain Casitas - Ocotillo

Cottage Guest House,University Area

The Saguaro Suite-SW Retreat w/Private Entrance

Modern Loft with Pool & Hot Tub-Views!

Modern Urban Flats: Prime Tucson Location

Jungle Escape • King Bed • Walk Downtown & U of A

Midtown pied-à-terre: Agua Linda Suite
Other great vacation rentals near Biosphere 2

Birder AirBnB near the beautiful Catalina mnts

Golden moments in Oro Valley/Tucson

Private 360 city and mountain view, hot tub

Luxury Home In Catalina Foothills Tucson

Horse house

Desert Retreat

Rural hilltop gem, 360 views

Mountain View Casita
Destinations to explore
- Mount Lemmon
- Mt Lemmon Ski Valley
- University of Arizona
- University of Arizona
- Sabino Canyon
- Saguaro National Park
- Arizona-Sonora Desert Museum
- Tucson Convention Center
- Tumamoc Hill
- Sabino Canyon Recreation Area
- Tucson Botanical Gardens
- Titan Missile Museum
- Reid Park Zoo
- Catalina State Park
- Tucson Museum of Art
- Mission San Xavier del Bac
- Pima Air & Space Museum
- Rialto Theatre
- Children's Museum Tucson
- Trail Dust Town
- Mini Time Machine Museum of Miniatures
- Casa Grande Ruins National Monument
- Picacho Peak State Park
- Roy P Drachman - Agua Caliente Regional Park





