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Vacation rentals in Depew

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Depew

Guests agree: these stays are highly rated for location, cleanliness, and more.

Apartment in Clarence
Meticulous Main St. Ranch 2 Bd Lux Apt. Rear Unit
This well-appointed, recently renovated, 1200 sq. ft. ranch duplex apt. is located on Main St in the heart of charming & historic Clarence, NY. The community is a beautiful, safe, and family friendly suburb of Buffalo, NY. The entire apt. is on one level, with four parking spaces next to the entrance. The beautiful open concept floor plan provides an abundance of natural lighting, creating a comfortable airy feeling, that is perfect for small gatherings, business travelers, and entertaining.
Apartment in Orchard Park
Cozy, comfortable and close to everything!
Super cozy downstairs apartment in lovely Orchard Park with separate entrance & parking in a private driveway Easy check in with keypad locks No cleaning fee or check out tasks Highmark Stadium is an easy walk for most guests at ~ 1.5 mi Comfortable, clean, and close to everything - Niagara Falls, sporting events, beaches, kayaking, nightlife, skiing Absolutely no animals without pre-approval; outdoor security camera; other guests may be staying in separate, upstairs apartment.
Apartment in Williamsville
**Village Home In Buffalo- BEST LOCATION!**
Welcome “home” and discover why Buffalo is called the ‘City of Good Neighbors’! Whether it’s for a day, week, or even longer, feel comfortable and cozy, in this 1 bedroom apartment. Being less than 2 miles from the Buffalo Niagara Int’l airport, a quick Uber ride will bring you to Williamsville and offer you a true Buffalo experience. Enjoy the small town vibe of the village, and allow Williamsville to be your gateway to adventure! (Downtown Buffalo- 9mi, Niagara Falls- 17mi. )

Stay near Depew's top sights

Wegmans34 locals recommend
Campfire Grill6 locals recommend
Broadway Driving Range & Miniature Golf3 locals recommend

Other great vacation rentals in Depew

Apartment in Depew
Fireman's Park View
Loft in Buffalo
LarkinVille Loft (Unit 1)
Guest suite in Cheektowaga
NO FEES 2 Night Discount! Lovely Lounge/Workspace
Apartment in Depew
Modern Oasis Pool & Hot Tub near Buf/Falls/Stadium
Apartment in Cheektowaga
Centrally located Apartment 5 Minutes from Airport
Apartment in Depew
Updated | Near Airport | The Poppy Home
Apartment in Lancaster
Upper Two bedroom apartment
Home in Buffalo
Bright, Charming, Private Home
Home in Lancaster
Charming Lancaster Home with Modern Amenities
Guest suite in Lancaster
"The Suite Spot", Adorable apartment with deck
Apartment in Cheektowaga
Rex's Flat near the Buffalo Airport
Home in Williamsville
Retro-styled home in the Village of Williamsville

Quick stats about vacation rentals in Depew

Total rentals

20 properties

Wifi availability

20 properties include access to wifi

Rentals with dedicated workspaces

10 properties have a dedicated workspace

Family-friendly rentals

10 properties are a good fit for families

Total number of reviews

1K reviews

Nightly prices starting at

$82 CAD before taxes and fees

Destinations to explore

  1. Airbnb
  2. United States
  3. New York
  4. Erie County
  5. Depew