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Vacation rentals in Doña Ana

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Top-rated vacation rentals in Doña Ana

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favourite
Guesthouse in Las Cruces
4.96 out of 5 average rating, 205 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Guest favourite
An outdoor patio is enclosed by wooden fencing and illuminated by string lights. A hot tub sits invitingly to one side, while comfortable seating arrangements include a light-colored sofa and wicker chairs surrounding a small table. A door leads to the interior of the container home.
Farm stay in Las Cruces
4.93 out of 5 average rating, 138 reviews

Matchbox desert oasis hot tub, pet friendly!

Come experience a spa like feel in the desert where tranquility awaits! This container home is new,clean,relaxing, romantic and comfortable! Surrounded by farm land, with a clear view of the Organ Mountains, makes the night extra special spending it in the hot tub on the private patio or in the beach like sand zen landscape. You can go explore the next door property enter the hen den feed the chickens along with ducks, turkey, goats and horses! Free farm fresh eggs with every stay! No farm smell

Top guest favourite
An aerial view of a Pueblo Style home is presented, showcasing a serene pool surrounded by a spacious outdoor area. The home is set against a backdrop of rolling hills and a cloudy sky. Desert vegetation is seen throughout the landscape, enhancing the natural beauty.
Home in Las Cruces
4.97 out of 5 average rating, 151 reviews

Desert Oasis with Pool

Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Top guest favourite
The living area features an open layout with a spacious couch, accent chairs, and a decorative coffee table on a colorful area rug. A television is positioned against a light wall, with artwork depicting floral designs hung above. Natural light enters through various windows.
Home in Las Cruces
4.99 out of 5 average rating, 127 reviews

Bonita Casita

This is a centrally located, remodeled 2 bedroom, 2 bathroom townhouse, very convenient to HWY 70, a straight shot to White Sands National Park, and Main Street, easy access to Downtown Las Cruces, home to Las Cruces's Farmer's Market. This townhouse features a split and open floor plan, full kitchen with everything you need to prepare a meal, dishwasher, microwave and gas cooking. You will also find an office and outdoor seating area. The property is located very near the lovely 4-Hills Park.

Top guest favourite
The exterior of a Southwestern home is showcased, featuring adobe-style architecture with a textured beige facade. A two-car garage is visible, along with a gravel front yard and desert landscaping, highlighted by rocks and sparse vegetation under a clear blue sky.
Home in Las Cruces
4.87 out of 5 average rating, 316 reviews

Casa Miranda, The Organ Mountains Looking House

Experience your clean, comfortable & spacious Southwestern home in Las Cruces, NM, now with a brand new refrigerated AC system. Your home has wonderful amenities: a fully stocked kitchen, washer/dryer, iron, comfortable beds (king & queen size), 65' flat screen TV in the living room with Wifi, secure two car garage, and a backyard with a breathtaking view of The Organ Mountains. Located minutes from both I-25/ US-70, easily get to downtown, Mesilla, NMSU, White Sands, and The Lincoln Forest.

Superhost
A cozy living room is depicted, featuring a comfortable dark sofa with decorative cushions. A large piece of wall art displays two figures sitting on a bench, creating a sense of connection. An antique trunk and a decorative green vase enhance the inviting space.
Earth homes in Las Cruces
4.84 out of 5 average rating, 623 reviews

Southwest Mexican Adobe Casa Historic District

This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Top guest favourite
The kitchen features blue cabinetry and colorful Talavera tile backsplash, enhancing its visual appeal. A window allows natural light to illuminate the space, while stainless steel appliances, including a microwave and dishwasher, are present. Wood countertops provide a warm contrast to the cabinetry.
Guesthouse in Las Cruces
4.96 out of 5 average rating, 125 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Guest favourite
An interior space showcases wooden accents and a warm ambiance. A dining table with vintage-style chairs is set for guests, featuring tableware arranged neatly. Various mirrors reflect natural light from skylights above, while unique windows with shutters add character to the room.
Camper/RV in Las Cruces
4.96 out of 5 average rating, 102 reviews

The Stranded Time Traveler; a timeless experience!

Like something out of a fairy tale, the time machine's beauties are enchanting and memorable. Set somewhere in the past and present, it is being held in a large storage yard (plenty of space) because of flux capacitor issues while time marches on. Centrally located, it is about 3 mins. from NMSU, 5 mins. from Old Mesilla, the Billy the Kid court house, and the Farmers Market, 20 mins. from Dripping Springs Natural Area, 40 mins from El Paso, and 45 mins. from White Sands National Park.

Superhost
The spacious living area features high ceilings with exposed wooden beams. Two plush sofas are positioned around a wooden coffee table, creating a comfortable seating arrangement. The open kitchen is visible in the background, showcasing wooden cabinetry and modern appliances.
Home in Las Cruces
4.86 out of 5 average rating, 306 reviews

Tuscan Villa Outdoor Living, Jacuzzi & Gym

This fully-furnished Tuscan style home is perfect for weekend getaways or longterm stays. With a jacuzzi and expanded outdoor living space the Greek-style Villa offers the comfort of home with a vacation vibe. Stream Netflix in the vaulted living room, soak in the outdoor hot tub, or enjoy your morning coffee lounging on the patio couch. This stylish space can be the romantic escape you're seeking or accommodate your group of 8. All this only minutes from all Las Cruces has to offer.

Superhost
The image captures a clear salt-water pool with sparkling turquoise water under a bright blue sky. Sunlight reflects off the surface, while a yellow flowering tree and lounging chairs are visible in the background, creating a serene outdoor space.
Shipping container in Las Cruces
4.91 out of 5 average rating, 1,057 reviews

Nature Retreat 12-min from Downtown (with pool)

Re-purposed 40-foot shipping container w/Ikea cabinets & furniture at edge of desert. Loft is 1 of 2 dwellings on 5-acre lot, private exterior doors & adjacent reserved parking. Picture window with wonderful view of Organ Mountains. Compact kitchen, Serta PillowTop queen size bed, full bathroom, LED lighting, cooled/heated by modern heat pump, Wi-Fi Internet. Pool access in season (usually April-October). Hike/bike from doorstep. Pet-friendly, see House Rules for details/cost.

Top guest favourite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces
5 out of 5 average rating, 271 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Top guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 188 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for Doña Ana vacation rentals

  1. Airbnb
  2. United States
  3. New Mexico
  4. Doña Ana County
  5. Doña Ana