Vacation rentals in Hampton County

Hank and Margie's Place

“PEACEFUL!! Nestled in the Lowcountry, a COZY LOOK AND Big City FEEL” – “Hank and Margie’s Place” This home is in a charming quiet neighborhood off Hwy 63/ 64, at the end of a cul-de-sac. "Perfect" for traveling construction/maintenance crews, health care professionals. Less than 1 mile to 1 local hospital, 10 Miles from Allendale County, 24 Miles from Colleton Regional, 44 Miles from Beaufort Memorial. Accommodates comfortably 4 Guests - 4 BR, 2.5 BA, FULL HOUSE GENERATOR & Very CLEAN.

The Early Branch Retreat | Secluded Forest Getaway

The Early Branch Retreat | Secluded Forest Getaway Extended stays receive exclusive discounts: 15% off weekly stays and 25% off monthly stays! Escape to South Carolina’s Lowcountry at this newly built retreat on nearly 52 wooded acres. Enjoy modern comforts, scenic trails, and a peaceful setting perfect for relaxing, reconnecting with nature, or exploring the surrounding area. Whether it’s a weekend escape, family getaway, or extended stay, The Branch Retreat offers a private outdoor haven.

Private Historic Home in Downtown Yemassee

Historic bungalow located just minutes from I-95 and a short drive to Beaufort. This cozy house is perfect for weary travelers or weekend getaways. Enjoy inviting living spaces, a fully equipped kitchen, and a large private backyard. Sit on the front porch under the grand live oaks or gather around the fire pit for a relaxing evening. Whether you are attending a wedding, graduating a Marine, antiquing, or hunting/fishing nearby, this is the place for you. Extended stays are welcome as well.

The Cottage

Reconnect with loved ones in this family-friendly place-- a peaceful setting in the South Carolina Low Country. We are centrally located in Estill, SC off of hwy 321. Our home is ideal for visiting hunters 🦌 (some of the best hunting in the state), tourist 📸, golfers⛳, or anyone desiring a peaceful escape🧘🏾‍♀️. Our home is clean, newly renovated, cozy, and fully electric. Explore nearby Lake Warren State Park, Beaufort, Hilton Head Island, and Savannah. Our home is ready for you!

Farmhouse Cottage

Stop off I95 - 10 mins. Quiet tranquility on 60 Acres. Wide open spaces. Perfect for a solo wellness retreat or romantic escape. Penelope Properties Inc. See the stars above at night. Be Still. Walk the 1 mile fitness trail. Or bring your easel and paint the day away. Read a good book with all the windows open and pasture breezes blowing through. Close to Charleston, Beaufort, Savannah or Bluffton and Hilton Head. Plus area hunting lodges. Starlink Wifi - Cottage close to private house

Cheerful 3 bedroom 2 bath residential home

Have your morning coffee on the front or back porch. Family dinner in the formal dining room or a BBQ in the back yard. This home sits on a 1 acre lot. It has hardwood floors throughout and carpet in the bedrooms. Explore nearby Beaufort, Hilton head, or Savannah Georgia which are all about 49 minutes from this location. Locals boast of hunting being one of the best in the state. Family reunions, girls or a boys trips, this beauty is clean functional cozy and ready for you!

Lowcountry Orchard Getaway

Anderson Orchards – A Lowcountry Retreat Relax in this 4BR home on 2 acres with a bridge, oak tree, muscadine vines, pear, and pecan trees. Ideal for families or groups (sleeps 12+), it’s a peaceful retreat near top destinations: Beaufort – 40 min (historic downtown) Hilton Head – 1 hr (beaches, golf) Savannah – 1 hr (riverfront, nightlife) Charleston – 1 hr 15 min (historic charm) Parris Island – 45 min (boot camp grads) Plenty of space to relax and explore!

The Pine Hideout

Just a quick jump from 95. Enjoy the sounds of nature. Surrounded by big pine trees. Very private. Home sits off the beaten path and tucked in. Only 2 miles off 95 for travelers! Plenty of room for trailers or multiple cars. Close to Beaufort and Paris island. Hilton Head island, Hunting Island, Edisto beach, Charleston and Savannah, all with in an hour, with beautiful scenery to make any drive enjoyable! Live oaks and Spanish moss umbrella the roads.

“Tiny house” nestled on beautiful farm

We are less than 1 mile off of I-95 in the Low Country of South Carolina. Our 62 acre farm is nestled in the “middle of nowhere, but close to every where”. We are located close Beaufort, Charleston and Savannah! Our Tiny House, which used to be our feed shed, offers beautiful scenery from the Red barn, Moss draped Live Oak trees, Pecan Grove, horses, goats, free range donkeys and more. We have a brand new Bathhouse with a full bath. Washer & Dryer too!

Superhost | Lowcountry Comfort | 3 BR | 1 GB Wi-Fi

Experience relaxed Southern comfort in this single-level 3BR/1.5BA Superhost home on a quiet 2.25-acre lot in Furman, SC, less than 1 minute (about 0.2 miles) from Town Hall and just off Hwy 601. Once home to Lizzie Young, Hampton County’s first female mayor and Furman’s first African American mayor (1990–1999), this historic stay blends local Black history, modern comfort, immaculate cleanliness, fast 1GB Wi-Fi, and peaceful surroundings guests love.

"Tranquil Tiny Cabin Retreat"

"Experience the tranquility of our secluded tiny cabin in Early Branch, SC. Surrounded by nature, this charming retreat offers a peaceful escape. Relax by the fire pit, fish in the private pond, and enjoy the cozy interior with small rooms, bathroom, and kitchen. Ideal for those seeking serenity and intimacy in a rustic setting. Book now for a unique getaway unlike any other."

Darlington's corner

This home is nestled in a charming neighborhood directly off of highway, 278. Making it perfect for traveling construction and healthcare professionals. Within walking distance to Fairfax\Allendale hospital only 10 miles from Hampton regional medical center. Experience the charm of the South in this Idyllic retreat.