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Vacation rentals in Hampton County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Hampton County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
Home in Fairfax

Hank And Margie's Place, TOO

“Field of Dreams!! - This home is Nestled in the Allendale County of the South Carolina Lowcountry surrounded by Corn Fields" “Hank and Margie’s Place, Too”. This home is in a charming neighborhood sitting on acreage with 7 Matured Pecan Trees. "Perfect" for a family with a small child (home is comfortable for 2 adults/1 small child), traveling small construction/maintenance crews of 2 adults, or a traveling health care professionals who seeks privacy. Only a few miles away from Hampton Regional Medical Center, Allendale County Hospital, Colleton Regional, and Beaufort Memorial Hospital. Accommodates comfortably 2-3 Guests - 3 BR, 1 Full Bath. (twin - bed is a toddler bed not suitable for adults)

A stately historic home features a wrap-around porch supported by brick columns. Rocking chairs are visible alongside flowering plants, with a blue flag bearing a white symbol gently waving. Large windows reflect the soft natural light, and greenery surrounds the inviting exterior.
Home in Brunson
5 out of 5 average rating, 3 reviews

Historic home near Walterboro and Hampton SC

Big Historic Home in small Hampton / Colleton County SC . Stately home with rambling wrap-around porch has maintained its original character for over 100 years. Walk the light-filled spacious c1900 home or the original c1867 home and feel a lifestyle of the past . Your breath will slow and your heart warm with serenity of yesteryear as you sit on the porch among heritage camellias, cedars, pecans, walnut, and magnolia trees, or simply sit with a fire of the wood stove in the thinking house.

Top guest favourite
Home in Varnville
5 out of 5 average rating, 20 reviews

Hank and Margie's Place

“PEACEFUL!! Nestled in the Lowcountry, a COZY LOOK AND Big City FEEL” – “Hank and Margie’s Place” This home is in a charming quiet neighborhood off Hwy 63/ 64, at the end of a cul-de-sac. "Perfect" for traveling construction/maintenance crews, health care professionals. Less than 1 mile to 1 local hospital, 10 Miles from Allendale County, 24 Miles from Colleton Regional, 44 Miles from Beaufort Memorial. Accommodates comfortably 4 Guests - 4 BR, 2.5 BA, FULL HOUSE GENERATOR & Very CLEAN.

Guest favourite
Home in Estill
4.96 out of 5 average rating, 73 reviews

The Cottage

Reconnect with loved ones in this family-friendly place-- a peaceful setting in the South Carolina Low Country. We are centrally located in Estill, SC off of hwy 321. Our home is ideal for visiting hunters 🦌 (some of the best hunting in the state), tourist 📸, golfers⛳, or anyone desiring a peaceful escape🧘🏾‍♀️. Our home is clean, newly renovated, cozy, and fully electric. Explore nearby Lake Warren State Park, Beaufort, Hilton Head Island, and Savannah. Our home is ready for you!

A rustic red cottage with a metal roof is set amidst lush greenery. The structure features a central porch supported by wooden beams. Nearby, a simple wooden fence encloses a grassy area, adding to the serene rural ambiance.
Cottage in Ridgeland
4.9 out of 5 average rating, 31 reviews

Farmhouse Cottage

Stop off I95 - 10 mins. Quiet tranquility on 60 Acres. Wide open spaces. Perfect for a solo wellness retreat or romantic escape. Penelope Properties Inc. See the stars above at night. Be Still. Walk the 1 mile fitness trail. Or bring your easel and paint the day away. Read a good book with all the windows open and pasture breezes blowing through. Close to Charleston, Beaufort, Savannah or Bluffton and Hilton Head. Plus area hunting lodges. Starlink Wifi - Cottage next to private house

A comfortable living area is furnished with a dark leather sofa set and a round coffee table. Decorative pillows add texture, while a lamp and a television provide functionality. The hardwood floor complements the rich tones of the furniture.
Home in Estill
4.75 out of 5 average rating, 48 reviews

Cheerful 3 bedroom 2 bath residential home

Have your morning coffee on the front or back porch. Family dinner in the formal dining room or a BBQ in the back yard. This home sits on a 1 acre lot. It has hardwood floors throughout and carpet in the bedrooms. Explore nearby Beaufort, Hilton head, or Savannah Georgia which are all about 49 minutes from this location. Locals boast of hunting being one of the best in the state. Family reunions, girls or a boys trips, this beauty is clean functional cozy and ready for you!

Guest favourite
An aerial view showcases a spacious 4BR home set on 2 acres. Surrounding greenery includes trees and open lawn areas, with pathways leading to the main entrance. Adjacent structures and a gravel road are visible in the background, emphasizing the property’s serene setting.
Home in Yemassee
4.94 out of 5 average rating, 77 reviews

Lowcountry Orchard Getaway

Anderson Orchards – A Lowcountry Retreat Relax in this 4BR home on 2 acres with a bridge, oak tree, muscadine vines, pear, and pecan trees. Ideal for families or groups (sleeps 12+), it’s a peaceful retreat near top destinations: Beaufort – 40 min (historic downtown) Hilton Head – 1 hr (beaches, golf) Savannah – 1 hr (riverfront, nightlife) Charleston – 1 hr 15 min (historic charm) Parris Island – 45 min (boot camp grads) Plenty of space to relax and explore!

Top guest favourite
A softly lit Tiny House is nestled beneath a moss-draped tree, creating a serene ambiance at night. Reflections can be seen in the water nearby, enhancing the tranquil setting. The surrounding grass is lush and well-maintained, contributing to the peaceful rural environment.
Farm stay in Yemassee
4.99 out of 5 average rating, 111 reviews

“Tiny house” nestled on beautiful farm

We are less than 1 mile off of I-95 in the Low Country of South Carolina. Our 62 acre farm is nestled in the “middle of nowhere, but close to every where”. We are located close Beaufort, Charleston and Savannah! Our Tiny House, which used to be our feed shed, offers beautiful scenery from the Red barn, Moss draped Live Oak trees, Pecan Grove, horses, goats, free range donkeys and more. We have a brand new Bathhouse with a full bath. Washer & Dryer too!

Top guest favourite
Home in Furman
5 out of 5 average rating, 11 reviews

Superhost | Lowcountry Comfort | 3 BR | 1 GB Wi-Fi

Experience relaxed Southern comfort in this single-level 3BR/1.5BA Superhost home on a quiet 1-acre lot in Furman, SC, less than 1 minute (about 0.2 miles) from Town Hall and just off Hwy 601. Once home to Lizzie Young, Hampton County’s first female mayor and Furman’s first African American mayor (1990–1999), this historic stay blends local Black history, modern comfort, immaculate cleanliness, fast 1GB Wi-Fi, and peaceful surroundings guests love.

Guest favourite
A spacious wooden deck is seen, surrounded by tall trees, providing a serene outdoor space. Two red chairs and a glass table are positioned on one side, while a wooden bench offers additional seating. Natural light filters through the greenery, enhancing the tranquil setting.
Cabin in Early Branch
4.92 out of 5 average rating, 53 reviews

"Tranquil Tiny Cabin Retreat"

"Experience the tranquility of our secluded tiny cabin in Early Branch, SC. Surrounded by nature, this charming retreat offers a peaceful escape. Relax by the fire pit, fish in the private pond, and enjoy the cozy interior with small rooms, bathroom, and kitchen. Ideal for those seeking serenity and intimacy in a rustic setting. Book now for a unique getaway unlike any other."

Guest favourite
The exterior of the cottage showcases a two-story structure with light-colored wooden siding and contrasting black trim. A welcoming entryway is highlighted by a small porch and a gentle staircase leading to the cottage door. Surrounding greenery enhances the peaceful rural setting.
Farm stay in Pineland
4.94 out of 5 average rating, 18 reviews

The Cottage

Welcome to our charming 1-bedroom, 1-bathroom cottage nestled on a picturesque family farm! Ideal for a peaceful retreat, this cozy cottage offers a perfect blend of rustic charm and modern amenities. Located less than an hour to Beaufort, Bluffton, and Savannah. *The loft bedroom is accessible only by a ladder, so please consider this when booking*

Guest favourite
A spacious bedroom features a four-poster bed topped with white and gray bedding. Two windows with light-filtering curtains provide natural light, while a dresser and a television are positioned in the room, creating a comfortable and functional space.
Home in Fairfax
4.96 out of 5 average rating, 24 reviews

Darlington's corner

This home is nestled in a charming neighborhood directly off of highway, 278. Making it perfect for traveling construction and healthcare professionals. Within walking distance to Fairfax\Allendale hospital only 10 miles from Hampton regional medical center. Experience the charm of the South in this Idyllic retreat.

Popular amenities for Hampton County vacation rentals