Skip to content

Vacation rentals in Mark Twain Lake

Find and book unique accommodations on Airbnb

When results are available, navigate with up and down arrow keys or explore by touch or swipe gestures.

Top-rated vacation rentals in Mark Twain Lake

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favourite
Home in Palmyra
Cozy country 2-bedroom home with a view.
Make some memories at this unique and family-friendly place. Enjoy the view of horses grazing while sipping your morning coffee on the front porch. Take a drive to historic Hannibal, MO (11 miles) and Quincy, IL (18 miles). Book a guided farm petting zoo tour with the owners and/or a riding lesson on one of their many rodeo horses. This house sleeps 6 with a king bed, queen bed, and couch fold-out queen bed. The hostess is right next door to assist with any of your needs during your stay!
Aug. 13 – 20
$153 CAD per night
Guest favourite
Tiny homes in Huntsville
O’s Barn Cabin - Small Town Livin'!
O’s Barn Cabin offers a simple and unique way of relaxing in rustic fashion! Our pet friendly tiny home is 532 sq. ft of open space and country character. The location is out of the city, yet just a couple miles from all of the stores you need. The little cabin is nestled down our shared private and peaceful driveway, with views of cattle grazing in the pasture right off the front porch at the right time of year. Our big screen projector and fire pit are two amenities you'll be sure to enjoy!
Jul. 5 – 12
$106 CAD per night
Guest favourite
Cottage in Philadelphia
Frogmore Cottage on 5-acre lake, Enjoy Nature!
Most suited for 2 people but can sleep 6. Enjoy nature… “frogs n more” on this five-acre lake on 25 well-manicured acres. Fabulous sunsets! For a tiny house it has a spacious lower level with vaulted ceiling and upper bedroom loft. Wifi & TV includes Netflix, Amazon, Hulu. Outdoor activity includes hammocks, swimming, boating (canoe, kayaks, john boat). For fishing we have boats, nets & fish-dressing station (bring poles & bait). Please list accurate number of guests when booking.
May 10 – 17
$287 CAD per night

Popular amenities for Mark Twain Lake vacation rentals

Other great vacation rentals in Mark Twain Lake

Guest favourite
Earth homes in Columbia
Creekside Cabin Getaway
Mar. 10 – 17
$159 CAD per night
Guest favourite
Home in Bowling Green
Peaceful Country Cottage
Sep. 28 – Oct. 5
$222 CAD per night
Guest favourite
Tiny homes in Mount Sterling
Tiny Treasure
Apr. 13 – 20
$97 CAD per night
Guest favourite
Home in Rocheport
Bluff House in Rocheport Missouri
Nov. 11 – 18
$180 CAD per night
Guest favourite
Guest suite in Clark
Woodland Fox Retreat
May 20 – 27
$132 CAD per night
Guest favourite
Place to stay in Columbia
*~Private Studio~ full bath & kitchenette
May 14 – 21
$76 CAD per night
Guest favourite
Cabin in Perry
Mark Twain Lake Cabin at Cedar Crest Place
Apr. 8 – 15
$225 CAD per night
Guest favourite
Condo in Monroe City
Lovely 2 Bed 2 Bath, Pet Friendly, Family Stay
Apr. 5 – 12
$124 CAD per night
Guest favourite
Condo in Monroe City
Enjoy a getaway at Mark Twain Lake
Aug. 2 – 9
$172 CAD per night
Guest favourite
Cabin in Monroe City
Mark Twain Lake Cabin
May 13 – 20
$207 CAD per night
Guest favourite
Home in Paris
Grit & Grace Lodge near Mark Twain Lake
Sep. 27 – Oct. 4
$278 CAD per night
Guest favourite
Apartment in Madison
Enjoy a Relaxing 2 Bed. Apt. in Quiet Small Town
Nov. 9 – 16
$104 CAD per night

Destinations to explore