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Vacation rentals in Mesilla

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesilla

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
Home in Mesilla
4.83 out of 5 average rating, 12 reviews

Cozy Historic Adobe Casita Steps from the Plaza

The Hacienda cozy adobe house just five minute walk to pwander the Heart of Old Mesilla plaza, shop boutiques, art galleries, and enjoy authentic New Mexican restaurants in one of the most beloved cultural districts. * Bedroom 1: Queen-size bed * Bedroom 2: Double bed * living Area: Sofa pull-out bed for extra guests Fully equipped Kitchen complete with all the essentials for cooking and dining Bathroom * A walk-in shower * Freestanding bathtub Free private parking & Front fenced yard

Superhost
A cozy living room is depicted, featuring a comfortable dark sofa with decorative cushions. A large piece of wall art displays two figures sitting on a bench, creating a sense of connection. An antique trunk and a decorative green vase enhance the inviting space.
Earth homes in Las Cruces
4.84 out of 5 average rating, 678 reviews

Southwest Mexican Adobe Casa Historic District

This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Top guest favourite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guesthouse in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Guest favourite
Home in Las Cruces
4.9 out of 5 average rating, 145 reviews

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV

Pecan Palace: luxe 4-BR near NMSU & White Sands. Tucked by pecan farms, this new retreat blends comfort + fun. Perfect for families, work trips, extended stays. ☞ EV charger ☞ Backyard hot tub under pergola ☞ Climate-controlled game lounge with pool table ☞ Foosball ☞ Poker ☞ Pac-Man ☞ Fully equipped chef's kitchen ☞ Plush bedrooms with blackout curtains ☞ Prime spot—1.5 mi to NMSU, Interstate I-10, dining & shopping ☞ Easy access to White Sands NP and downtown

Top guest favourite
Two colorful planters holding purple cactus are positioned beside a large window on the exterior wall of the adobe home. The warm-toned stucco walls and terra-cotta tiled flooring add to the inviting appearance of the entryway, which is framed by traditional wooden beams above.
Home in Mesilla
4.96 out of 5 average rating, 138 reviews

Mesilla 1869 Adobe 2 blocks from plaza

I purchased this beautiful home built circa 1869 all Adobe in May 2019 and I want to share it with you! I am living in this home as one of my primary residences but I’m traveling the world and will make it available so you can also enjoy it. Authentic wood beams “vigas” and “latillas”, original kitchen wood floor, painted cement floors (by the previous artist owner), 3 foot thick adobe interior walls. Just steps to the Mesilla Plaza, shops, restaurants!

Superhost
A bright and airy living space features a blend of modern and vintage elements. A dining table is elegantly set with vibrant decor, while yellow accent chairs provide a pop of color. A cozy blue sofa is positioned nearby, alongside a window adorned with cheerful curtains.
Home in Mesilla Park
4.93 out of 5 average rating, 376 reviews

One bedroom casita in Mesilla Park with hot tub

This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building has stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Top guest favourite
A spacious room features a regal four-poster bed adorned with golden bedding. Antique-style lamps on either side illuminate the space, while a cozy seating area in the corner invites relaxation. Exposed wooden beams and a decorative fireplace add to the historic Southwestern charm.
Guest suite in Mesilla
4.99 out of 5 average rating, 139 reviews

Josefina's King Suite in Mesilla Plaza.

Josefina's King Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious King Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, AC, plush bathrobes and more. If the King is already booked, please check out our Queen Suite!

Top guest favourite
A spacious outdoor area showcases a desert landscape with gravel and low-lying plants. A large round table is accompanied by a bright red umbrella, offering shade. The casita's entrance features a patio with seating and a welcoming purple trim, enhancing the inviting exterior.
Home in Mesilla
4.98 out of 5 average rating, 201 reviews

Charming Adobe One Block from the Mesilla Plaza

Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Superhost
The exterior of a recently renovated tiny home features a modern design with a combination of beige and orange walls. A welcoming entrance is flanked by two planters, while a stone pathway leads to the door. Lush green grass enhances the outdoor space.
Tiny homes in Las Cruces
4.92 out of 5 average rating, 243 reviews

Modern New Mexico Loft in the heart of Las Cruces.

Recently renovated tiny home with a loft-style bedroom. Many unique features will greet you in this very unusual space for Las Cruces. Downstairs there is a living room with a queen pull-out couch and a renovated kitchen that has everything you will need except an oven. Full 4 burner cooktop, microwave, full-sized fridge, and an eating bar. There is a small desk area for working, a shower bath (which is downstairs ), and a wonderful small outdoor space.

Top guest favourite
An adobe-style home is displayed, featuring a gravel pathway leading to an entrance framed by wooden gates. Two turquoise chairs sit beside a small table under a budding tree. Planted flowers in bright pots add color to the exterior, enhancing the welcoming appearance.
Home in Mesilla
4.98 out of 5 average rating, 174 reviews

Sombra Del Valle in Historic Mesilla.

Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Top guest favourite
Guesthouse in Mesilla
4.99 out of 5 average rating, 220 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Mesilla
4.99 out of 5 average rating, 248 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Popular amenities for Mesilla vacation rentals

When is the best time to visit Mesilla?

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Frequently Asked Questions

  • What are the best places to stay in Mesilla?

    Staying near the Mesilla Plaza places you close to markets, art galleries, and dining. The nearby La Mesilla and historic neighborhoods feature a mix of casitas, adobe inns, and vacation rentals.

  • What are the best things to do in Mesilla with kids?

    Children often enjoy interactive museums, pueblo-style historic sites, and community events held around the plaza. Visiting local bakeries or joining cultural workshops can provide family-friendly activities.

  • What are some of the best things to do in Mesilla?

    Explore the historic Mesilla Plaza, browse artisan shops, and discover galleries featuring local artwork. The area has regional cuisine, cultural sites, and frequent outdoor markets throughout the year.

  • How is the weather in Mesilla?

    Mesilla has mild winters near 24–56°F (-5–13°C) with little rain and hot, sunnier summers peaking at 95°F (35°C). Most rainfall occurs in July and August, so light layers and sun protection are recommended for outdoor plans.

  • When is the best time to visit Mesilla?

    Spring and fall are often recommended for milder temperatures around 70–85°F (21–30°C) and comfortable weather for outdoor exploration. These seasons also bring local markets and festivals to the plaza area.

  • What are the best places to visit in Mesilla?

    The Mesilla Plaza is often suggested for its charming adobe buildings and regional shops. Local museums and galleries around the square display a blend of Southwestern art and history.

  • What are some hiking trails in Mesilla?

    Trails near Mesilla often wind through desert landscapes, offering views of native flora and regional mountain ranges. Look for community parks and nature reserves just outside town for accessible paths.

  • What are some family activities we can do in Mesilla?

    Families explore the Mesilla Plaza, join educational walking tours, or visit local museums highlighting regional history and culture. Outdoor markets and seasonal events often include activities suitable for all ages.

  • What are some of the best day trip ideas from Mesilla?

    You can explore surrounding desert parks, visit neighboring historic towns, or join wine tastings at local vineyards. Outdoor enthusiasts often enjoy nearby mountain trails and nature reserves.

  • Are there any pet friendly accommodations available in Mesilla?

    Pet-friendly stays are available in Mesilla, particularly in vacation rentals and some smaller inns. Check for easy access to outdoor areas and pet-welcoming patios around the plaza.

  • What are some local tips for visiting Mesilla?

    Wear comfortable shoes, as plaza streets are mostly walkable with brick or adobe paths. Early mornings and evenings are pleasant for exploring, especially during outdoor markets or community festivities.

  • What is Mesilla known for?

    Mesilla is known for its well-preserved plaza, locally rooted New Mexican cuisine, and adobe architecture. The town has a long cultural history, including significance in the region's border and railroad stories.

  • What are the best hidden gems to explore in Mesilla?

    Explore tucked-away courtyards, local weaving studios, and lesser-known galleries dotted around historic streets. Neighborhood bakeries and specialty shops often reveal unique flavors and handmade crafts.

  • What are the best foods to try in Mesilla?

    Mesilla is known for New Mexican cuisine, including chile-infused dishes, tamales, and locally made salsas. You might also experience traditional baked goods and Southwestern-style enchiladas at area restaurants.

  • What should I bring for a trip to Mesilla?

    Pack comfortable clothing for warm, sunny days, a light layer for cooler evenings, and sun protection such as a hat and sunscreen. Walking shoes are useful for exploring plaza streets and local shops.

  • What is the nightlife in Mesilla like?

    Mesilla has cozy wine bars, historic cantinas, and live music venues centered around its adobe-lined streets. Evenings often feature a relaxed, social atmosphere with regional food and music.

  • What are the most popular events or festivals in Mesilla?

    Mesilla hosts frequent arts and crafts fairs, a popular Day of the Dead celebration, and regional food festivals, often centered around the plaza and nearby streets. Holiday events fill the area with music, luminarias, and local gatherings.

  • Are there family friendly vacation rentals in Mesilla?

    Mesilla has a range of family-friendly vacation rentals, especially close to the plaza and historic neighborhoods. Many homes feature spacious layouts and easy access to public spaces and local attractions.

Quick stats about vacation rentals in Mesilla

  • Total vacation rentals

    Explore 70 vacation rentals in Mesilla

  • Nightly prices starting at

    Mesilla vacation rentals start at $56 CAD per night before taxes and fees

  • Verified guest reviews

    Over 7,390 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wifi availability

    70 of Mesilla vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests—averaging 4.9 out of 5!

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