Vacation rentals in Depew

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Top-rated vacation rentals in Depew

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite

Home in Buffalo

4.94 out of 5 average rating, 510 reviews

From Home Away To Home To Stay!

Relax in the charming home in a great location w/everything you need at your fingerprints. Spacious living room w/smart TV, fast internet & a day bed & pullout loveseat. Situated near shops & restaurants. 10 mins from UB. Mins away from I-90/290 Thruways. 15 mins to downtown, 22 min to Niagara Falls. Prepare meals in an inviting kitchen w/coffee & the cookware necessary to accommodate your needs. Both bdrms have queen size mattresses. No parties, events, pets or hosting other people are allowed.

Jun. 10 – 17

$207 CAD per night

Guest favourite

Home in Cheektowaga

4.99 out of 5 average rating, 103 reviews

Unique & charming-Great central location!

Welcome to this Unique and Charming house! Exposed beams and earth tones gives this home a comfortable feel while being centrally located. The Buffalo airport and major highways are literally a few minutes away. This gem is 10 minutes from downtown Buffalo featuring museums, art galleries, amazing restaurants, shopping, the Keybank Center(Buffalo Sabres), Sahlen Field (Buffalo Bisons) and beautiful waterfront. Niagara Falls and Highmark Stadium (home of the Buffalo Bills) are 20 minutes away.

Feb. 14 – 21

$270 CAD per night

Guest favourite

Apartment in Depew

4.81 out of 5 average rating, 318 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Nov. 7 – 14

$103 CAD per night

Guest favourite

Apartment in Williamsville

4.93 out of 5 average rating, 231 reviews

**Village Home In Buffalo- BEST LOCATION!**

Welcome “home” and discover why Buffalo is called the ‘City of Good Neighbors’! Whether it’s for a day, week, or even longer, feel comfortable and cozy, in this 1 bedroom apartment. Being less than 2 miles from the Buffalo Niagara Int’l airport, a quick Uber ride will bring you to Williamsville and offer you a true Buffalo experience. Enjoy the small town vibe of the village, and allow Williamsville to be your gateway to adventure! (Downtown Buffalo- 9mi, Niagara Falls- 17mi. )

Sep. 14 – 21

$179 CAD per night

Guest favourite

Loft in Buffalo

4.93 out of 5 average rating, 520 reviews

LarkinVille Loft (Unit 1)

If this listing is not available please check out my other listing. This 1st floor loft features an open concept kitchen & living room. The bedroom and bathroom are off this space. Large windows in the living area & bedroom provide ample natural light along with window coverings. This is a multi-unit building with permanent tenants in the upper and front apartments. Noise is typically low as the spaces are well insulated and the brick structure is a natural sound barrier

Nov. 3 – 10

$135 CAD per night

Guest favourite

Guest suite in Buffalo

4.98 out of 5 average rating, 236 reviews

Suite Sherry's - Your home away from home!

Come feel at home in this quiet & cheery private suite setting attached to the rear of our home and enjoy view of park like yard. Central location in Erie County!Only 20 Min.to Buffalo, to Peace Bridge (Canada), to the Buffalo Airport and the Galleria Mall. 10 minutes to New Era Field (Buffalo Bills) or to Harvest Hill Golf Course, Chestnut Ridge park, 15 min to Woodlawn beach, 15 min to Hamburg Fair, 15 min to Basilica or Botanical Gardens, 20 min from Riverworks.

Jun. 5 – 12

$115 CAD per night

Guest favourite

Apartment in Depew

4.88 out of 5 average rating, 56 reviews

Updated | Near Airport | The Poppy Home

Welcome to The Poppy Home! Enjoy a stay in our newly renovated *pet friendly* home! This is the perfect place for professionals on business, couples visiting the area, or those flying in to see family. Conveniently located within 8 minutes of the Galleria Mall, 10 minutes of the Buffalo Airport, 15 minutes to KeyBank Center, and only 20 minutes to Highmark Stadium. Home comfortably sleeps two, but we can accommodate four with our couch (converts to a full).

Jun. 29 – Jul. 6

$184 CAD per night

Superhost

Apartment in Buffalo

4.88 out of 5 average rating, 52 reviews

Relaxing and Cozy Apartment 5 Minutes from Airport

Peaceful quiet 1 bedroom apartment located on quiet street in Cheektowaga 5 minutes from airport and 12 minutes from downtown Buffalo. Centrally located near tons of restaurants and the Galleria mall. Perfect spot to getaway and enjoy your vacation without having to deal with the rules / regulations of hotels. Park right outside your door and arrive at your room in seconds. I am dog friendly with invisible fence in backyard. Smart TV, WiFi, & Keurig included

Feb. 2 – 9

$138 CAD per night

Guest favourite

Guest suite in Lancaster

4.9 out of 5 average rating, 154 reviews

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

Dec. 1 – 8

$162 CAD per night

Guest favourite

Apartment in Depew

4.81 out of 5 average rating, 43 reviews

Modern 2-bedroom upper apartment with free parking

Enjoy a stay in our updated, modern apartment! This is the perfect place for professionals on business or for couples or families visiting the area. Conveniently located within 10 minutes of the Buffalo Airport and the Galleria Mall and within 20 minutes of KeyBank Center and Highmark Stadium. You're guaranteed a great stay in our cozy modern space! Apartment comfortably sleeps four.

Jan. 20 – 27

$178 CAD per night

Superhost

Home in Buffalo

4.84 out of 5 average rating, 245 reviews

Home from Home

Two bedroom house with deck in safe suburban neighborhood best suited for one or two couples or a couple with a child. Minutes from the historic village of Williamsville with shopping and entertainment. 10 mins from downtown Buffalo. Minutes from state park. 6 mins to UB. 25 minutes to Niagara Falls. Fast Wifi, Alexa and Smart TV with streamable apps and local channels.

Mar. 6 – 13

$238 CAD per night

Guest favourite

Home in Depew

4.89 out of 5 average rating, 47 reviews

Cozy 3 bd I & half bath home-4 min to airport

Our centrally located place welcome you with all of amenities and comfort you will need during your trip.Walking distance all kinds of restaurants.1-4 minutes drive Wegmans,Walgreens, Walmart,Tops,Gallaria Mall,Gabe’s,Airport,Amtrak Station .30 minutes drive Niagara Falls.20 minutes drive to Highmark stadium.

Feb. 7 – 14

$217 CAD per night