Vacation rentals in La Mesa

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Top-rated vacation rentals in La Mesa

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favourite
Guesthouse in La Mesa
Da Hui Hut-Beachy home/La Mesa’s best view and spa
Da Hui Hut is a very private oasis uniquely situated at the top of San Diego county's magnificent Mt. Helix. At roughly 1,300 feet above sea level, Mt. Helix is the crown jewel of natural landmarks in the area. The landscape provides bountiful views, and the large deck is positioned perfectly to see it all. It feels like you're on top of the city! Inside, guests will encounter Californian and Hawaiian inspired decor as they collide with wooden walls to compose a symphony of color and good vibes.
Sep. 1 – 8
$235 CAD per night
4.98 out of 5 average rating, 125 reviews
Guest favourite
Guesthouse in La Mesa
Anna's Historic Stone Cottage w/panoramic View!
Welcome to Anna's Historic Stone Cottage! The 110 year old cottage has been transformed into the perfect combination of romantic and rustic for a dream-worthy getaway. The 280sq ft cottage features stunning, panoramic views of the San Diego skyline while offering rooftop seating for sunrise and sunset viewing. The Cottage is conveniently located 20 minutes from the world famous San Diego zoo and most other must-see, tourist spots. Amenities for special occasions offered too. Check out our menu!
Apr. 27 – May 4
$377 CAD per night
4.9 out of 5 average rating, 273 reviews
Guest favourite
Home in La Mesa
Cottage in the Garden! New! Modern!
COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!
Oct. 2 – 9
$217 CAD per night
4.94 out of 5 average rating, 172 reviews

Popular amenities for La Mesa vacation rentals

Stay near La Mesa's top sights

Grossmont Center48 locals recommend
Mt. Helix Park92 locals recommend
Trader Joe's52 locals recommend
Lake Murray Community Park11 locals recommend
DZ Akins24 locals recommend
La Mesa Springs Shopping Center7 locals recommend

Other great vacation rentals in La Mesa

Guest favourite
Guest suite in La Mesa
Hacienda de Las Campanas
Nov. 13 – 20
$241 CAD per night
4.94 out of 5 average rating, 161 reviews
Superhost
Condo in La Mesa
La Mesa Village Condo ~ SDSU, Beaches, Downtown
Apr. 27 – May 4
$232 CAD per night
4.92 out of 5 average rating, 117 reviews
Guest favourite
Home in La Mesa
Newer "Manor Studio"
Sep. 3 – 10
$162 CAD per night
4.84 out of 5 average rating, 169 reviews
Guest favourite
Bungalow in La Mesa
Casa de Pueblo - Hot Tub, Fire Pit La Mesa Village
Jan. 27 – Feb. 3
$323 CAD per night
4.97 out of 5 average rating, 128 reviews
Guest favourite
Guest suite in La Mesa
Stylish Boho Studio | Walk to Cafes | Outdoor Living
Aug. 7 – 14
$303 CAD per night
4.9 out of 5 average rating, 101 reviews
Guest favourite
Guest suite in La Mesa
Charming Suite in Historic Home
Jul. 10 – 17
$198 CAD per night
4.9 out of 5 average rating, 172 reviews
Guest favourite
Home in La Mesa
Clean 1BR/1BA Guest House Peaceful Private Casita
Apr. 24 – May 1
$220 CAD per night
4.96 out of 5 average rating, 480 reviews
Guest favourite
Guesthouse in La Mesa
Mountain top view getaway loft
Nov. 26 – Dec. 3
$355 CAD per night
4.98 out of 5 average rating, 110 reviews
Guest favourite
Home in La Mesa
Cozy, Single Bedroom, Detached Guest House
Feb. 25 – Mar. 4
$194 CAD per night
4.96 out of 5 average rating, 50 reviews
Guest favourite
Guest suite in La Mesa
Emerald King Wellness Suite w/ Sauna & Workspace
Aug. 27 – Sep. 3
$192 CAD per night
5.0 out of 5 average rating, 30 reviews
Guest favourite
Guesthouse in La Mesa
Private 1 BR Paradise retreat
Feb. 8 – 15
$184 CAD per night
5.0 out of 5 average rating, 58 reviews
Guest favourite
Home in La Mesa
Escape to tranquility: the perfect retreat
May 7 – 14
$164 CAD per night
5.0 out of 5 average rating, 41 reviews

Quick stats about vacation rentals in La Mesa

Total rentals

540 properties

Rentals with dedicated workspaces

320 properties have a dedicated workspace

Rentals with a pool

150 properties have a pool

Pet-friendly rentals

170 properties allow pets

Family-friendly rentals

260 properties are a good fit for families

Total number of reviews

22K reviews

Destinations to explore

  1. Airbnb
  2. United States
  3. California
  4. San Diego County
  5. La Mesa