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Vacation rentals in Melrose

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Top-rated vacation rentals in Melrose

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Cottage in Hawthorne

4.85 out of 5 average rating, 110 reviews

Live Oak Oasis on Morris Lake

Unspoiled nature greets your every turn at this charming 650 SF lakefront retreat. A short distance from 10 of Florida's finest 1st magnitude springs, ranging from 30 - 90 minute drive, makes the location a perfect basecamp for adventure travel. Rest beneath the shade of Live oaks that pull the breeze ashore. Enjoy Sand hill cranes and hummingbirds from the cabana. Incredible sunsets from new dock. Paddle boat & paddle boards available for adventures. WiFi, Netflix, Laundry, HOT outdoor shower!

Oct. 25 – Nov. 1

$162 CAD per night

Guest favourite

Home in Melrose

4.91 out of 5 average rating, 67 reviews

Three Bedroom House on Private Scenic Lake Mable

Located on pristine (no gas engines) swimming and fishing Lake Mable, this cheerful home is the perfect spot for a fun filled family vacation or just a relaxing weekend getaway. Enjoy the peaceful sounds of nature as you sit and watch the sunset over the lake, roast some marshmallows over the firepit, or just relax by the lake with a fishing rod in hand. You may see Sandhill Cranes, Red-headed Woodpeckers, or even a few deer. Let your worries drift away and enjoy the tranquility around you.

Aug. 13 – 20

$198 CAD per night

Guest favourite

Home in Earleton

4.97 out of 5 average rating, 177 reviews

Lake House Escape & Play

1950's remodeled home. Dock access is approx 500ft from house down to Big Lake Santa fe 7x3mi & up to 30ft deep. Perfect for skiing & fishing. Boat trailer between houses or along road. Use of dock & canoe free. The vacation venue next door, called "Boat House", has a boat ramp. It is $20 fee to launch boat or free ramp in Melrose, 3.5mi away. PLEASE be careful at dock. It is very sturdy but the hurricanes have washed out the sides. Grab 1 of the flashlights for a night walk to guide you.

Jul. 11 – 18

$195 CAD per night

Guest favourite

Cabin in Hawthorne

4.95 out of 5 average rating, 129 reviews

Charming Lakefront Log Home

Welcome to your perfect lake retreat! Located on a no public access lake. This charming log home has a private dock and boat ramp suitable for launching your boat for fishing or skiing. There are kayaks on premises for use. This is an ideal location to enjoy North Florida’s lake life with family, friends, or work retreat. Includes a fully stocked kitchen, covered porch, fire pit, gas grill, and WiFi if you feel the need to plug in. NOT suitable for parties or events. NO loud noise, please.

Jun. 24 – Jul. 1

$278 CAD per night

Guest favourite

Apartment in Melrose

4.88 out of 5 average rating, 168 reviews

The Orchid of Lake Santa Fe

Melrose Bay on Lake Santa Fe This apartment is newly remodeled. It features new cabinets, new appliances, a private porch and lovely furnishings, WIFI and cable. Downtown Melrose is in walking distance with three restaurants (one is the famous Blue Water Bay), public library, post office, grocery store, dollar store and Ace. Bring your boat and launch at the nearby boat ramp. Lake Santa Fe is a recreational lake with clean spring fed water for swimming, boating, skiing and fishing.

Jul. 28 – Aug. 4

$153 CAD per night

Guest favourite

Tiny homes in Alachua

4.95 out of 5 average rating, 263 reviews

Ela's Tiny House: Springs, Trails & Disc Golf!

Ela's Tiny House is a 40ft Thomas School Bus converted into a unique and elegant experience! Nestled on 28 Acres of beautiful Florida nature, you can soak up the sun and unwind. Enjoy laying in a hammock and star gaze, catch a stunning sunrise or play a round of disc golf. Paddle board the Santa Fe River, swim with manatees @ Ichetucknee Springs, or soak in the cool waters @ Blue Springs. The Historic town of Alachua, High Springs and Gainesville all within a 20 min drive.

Jan. 10 – 17

$113 CAD per night

Guest favourite

Cottage in Melrose

5.0 out of 5 average rating, 55 reviews

The Nest on Lake Santa Fe in Melrose, FL

The Nest is a beautiful two-story cottage on Lake Santa Fe. Enjoy some peace and serenity, catch monster bass, or bring your ski boat for high-speed fun. We are located just 20 minutes from Gainesville and UF. The Nest is great for a weekend getaway or a week of peaceful relaxation. We do not allow parties or events out of respect for our neighbors and we allow a maximum of 6 guests (max 4 adults). Absolutely no animals are allowed on the property at any time for any reason.

Sep. 27 – Oct. 4

$272 CAD per night

Cottage in Keystone Heights

4.84 out of 5 average rating, 192 reviews

"Love Shack"

Nice little country lake house with a quiet safe environment. The house is simple and meant as a getaway from the hustle of the city. There is lake access with a canoe and kayak available for your enjoyment. The home is small and not meant for a large Amount of people. The area offers a quiet "getaway". The home has three small bedrooms, kitchenette, 1.5 bathrooms, living room and a small dinning area looking at the lake. The hot tub is available with advance notice.

Feb. 12 – 19

$131 CAD per night

Guest favourite

Apartment in Waldo

4.99 out of 5 average rating, 148 reviews

Fernbank on beautiful Lake Alto. Laketime Getaway

Visit this beautiful, tranquil lakeside spot for an amazing getaway. It's a six acre property, an inspiring place to study, write, or get work done with fun things to do while on a break. Swim, kayak, canoe, paddle board or enjoy sitting on the dock. Visit the barn for basketball, ping pong, and corn hole. It's a studio apartment with a private bathroom and beds for four, plus two couches and air beds available. Note: This is an upstairs apartment.

May 27 – Jun. 3

$161 CAD per night

Guest favourite

Cottage in Keystone Heights

4.9 out of 5 average rating, 78 reviews

Charming lake front cottage

Keep it simple at this peaceful and centrally-located cottage on Little Lake Geneva. Clean and freshly updated interior with canoe and fishing gear for your outdoor enjoyment. This charmer is located near popular springs for diving as well as hiking and biking trails. Jacksonville and Gainesville are within easy driving distance. Come to “get away from it all” and enjoy the peaceful, quiet atmosphere that helps to unwind and recharge.

Jan. 23 – 30

$142 CAD per night

Guest favourite

Apartment in Melrose

4.98 out of 5 average rating, 66 reviews

Lakefront Retreat Apartment Remodeled, Premium Bed

Private lake home on Big Lake Santa Fe is the perfect place to unwind and enjoy gorgeous sunset views. The rental unit is an upstairs separated apartment. It has a cedar interior with a cabin feel has recently been renovated with new appliances, flooring and updated bathroom with walk in shower. Bring your boat to cruise the lake or fish and tie up at our dock. Enjoy swimming, water skiing, fishing or just relaxing on the deck.

Dec. 5 – 12

$143 CAD per night

Guest favourite

Home in Citra

4.99 out of 5 average rating, 348 reviews

All About Horses

Our place is close to I 75 half way between Gainesville and Ocala and is good for couples, solo adventurers, and business travelers. Spend a week or weekend in a sunny Florida on a horse farm. We have a newly renovated, spacious modular home 30mins from Gainesville (home of the Florida Gators). This immaculate and charming residence is fully furnished with four bedrooms and a large living room on owners' 40-acre horse farm.

Sep. 26 – Oct. 3

$116 CAD per night

Vacation rentals for every style

Get the amount of space that is right for you.

Hotels

Stylish accommodations and amenities

Unique stays

Spaces that are more than just a place to sleep

Homes

Comfortable places with all the essentials

Popular amenities for Melrose vacation rentals

Free parking on premises

Air conditioning

Stay near Melrose's top sights

Blue Water Bay23 locals recommend

Fryer's Chicken10 locals recommend

Betty's Pizza & Subs9 locals recommend

Williamson's Food Store7 locals recommend

Bryan's Ace Hardware3 locals recommend

Chiappini Gulf Station4 locals recommend

Other great vacation rentals in Melrose

Guest favourite

Home in Melrose

5.0 out of 5 average rating, 33 reviews

The Lily Pad-Spring& Summer Days at the Lake!

Nov. 4 – 11

$290 CAD per night

Guest favourite

Cabin in Melrose

5.0 out of 5 average rating, 27 reviews

RUSTIC FISHING CABIN ON SWAN LAKE, MELROSE

May 16 – 23

$241 CAD per night

Guest favourite

Guesthouse in Keystone Heights

4.97 out of 5 average rating, 75 reviews

Cottage on Brooklyn Bay

Oct. 31 – Nov. 7

$201 CAD per night

Guest favourite

Cottage in Hawthorne

4.96 out of 5 average rating, 76 reviews

Modern Cottage on Private Spring Fed Lake

Sep. 13 – 20

$173 CAD per night

Guest favourite

Home in Melrose

5.0 out of 5 average rating, 27 reviews

Your Dream Lakefront Fully Loaded Escape Awaits

Sep. 14 – 21

$351 CAD per night

Guest favourite

Home in Melrose

4.96 out of 5 average rating, 81 reviews

Sante Fe Lakehouse with Canal for your Boat

Oct. 4 – 11

$390 CAD per night

Guest favourite

Farm stay in Hollister

5.0 out of 5 average rating, 21 reviews

Two Old Goats Farm Airbnb

Sep. 30 – Oct. 7

$157 CAD per night

Guest favourite

Cottage in Interlachen

4.95 out of 5 average rating, 65 reviews

Sand Lake Getaway

Sep. 25 – Oct. 2

$156 CAD per night

Quick stats about vacation rentals in Melrose

Total rentals
10 properties
Local attractions
Blue Water Bay, Fryer's Chicken, and Betty's Pizza & Subs
Popular amenities
Gym, BBQ grill, and Laptop-friendly workspace
Wifi availability
10 properties include access to wifi
Total number of reviews
510 reviews
Nightly prices starting at
$55 CAD before taxes and fees

Destinations to explore