
House vacation rentals in Santee
Find and book unique houses on Airbnb
Quick stats about house rentals in Santee

Total vacation rentals
Explore 50 vacation rentals in Santee

Nightly prices starting at
Santee vacation rentals start at $56 CAD per night before taxes and fees

Verified guest reviews
Over 1,440 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space and kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Vacation rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
50 of Santee vacation rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santee rentals

4.9 Average rating
Santee stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in Santee
Guests agree: these houses are highly rated for location, cleanliness, and more.

Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa
✨ Luxury Hillside Retreat | Private Entrance | Saltwater Pool & Spa Enjoy this luxuriously furnished 4-bedroom, 2-bath home in Fletcher Hills, CA, perched on a hill with stunning mountain and San Diego city views. Relax in your private saltwater pool and jacuzzi with color-changing LED lights, or unwind indoors with full kitchen access, high-speed Wi-Fi, and smart TVs with Netflix. Perfect for couples, business travelers, and families, this cozy yet elegant retreat makes you feel right at home.
4.94 out of 5 average rating, 156 reviews
Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min
4.94 out of 5 average rating, 162 reviews
San Diego Casita for 6 Morey de Prieto Surf Ranch
The Morey de Prieto Surf Ranch is truly awesome! Reserve your stay in this 2 Bed/1 Bath 650 sq. ft. casita for six. Home includes kitchen with GE electric cooktop, refrigerator, microwave/air fryer, rice cooker, mixer for drinks, sink with prep trays, Moen faucet fixtures, gorgeous shower, Krups coffee maker, 50" smart TV equipped with WiFi and NetFlix, mountain views, workspace and a sofa bed. Relax on s 240 sq. ft. private deck with fire pit, adirondack chairs and BBQ. Level 1 EV Charger.
4.93 out of 5 average rating, 151 reviews
Cozy 4bd Family Home near all SD Attractions!
This sunny, 4bd home located on a private cul de sac in Mount Helix. Perfect for both family vacations & business trips. Conveniently situated near freeways & grocery stores. It’s comfortably furnished with a fully equipped kitchen. We have new beach chairs towels & toys! Pac-n-play available, fast Wi-Fi and smart TVs. The home features a quiet, private fenced backyard, BBQ, & covered patio. There’s plenty of room for kids to play! Please note that parties and events are not allowed.
4.85 out of 5 average rating, 427 reviews
5 Bed Zen Oasis | Fire Pit, BBQ, Laundry, Parking
Capture the essence of San Diego in our 3 bedroom house hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 10 guests with beautiful outdoors and garden, fire pit table, BBQ grill, FREE laundry, central A/C and heating, 5 comfortable king and queen size beds, plenty of sheets and towels, 4 large HDTVs, Netflix, Max, Hulu, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!
4.85 out of 5 average rating, 281 reviews
Zen Retreat: 3-Bedroom Oasis near La Mesa Village
Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.
4.96 out of 5 average rating, 143 reviews
San Diego Oasis- A Retro Retreat w/ King Size Bed!
Welcome to San Diego Oasis, a retro retreat--a mid-century modern oasis in sunny San Diego! This stylish home combines classic charm with all the modern upgrades you desire. Unwind by the sparkling pool, enjoy a friendly game of air hockey or corn hole, board games or enjoy s'mores around the gas fire pit . The retro retreat is the perfect blend of comfort, convenience, and timeless design. SD's most popular attractions are all within a 20-30 minute drive. Only 20 minutes to the beach!
4.92 out of 5 average rating, 102 reviews
Your SD Home Away from Home-Big Family Retreat
Not just a stay—a space to belong. This 4BR San Diego retreat is designed for real connection, with room to breathe, soft touches throughout, and everything you need to feel at home from the moment you arrive. Laugh late into the night, greet sunlit mornings with coffee in the garden, and linger over unhurried meals. Become a local in one of San Diego’s safest, quietest neighborhoods—your home base for memory-making, firelit stories, and the kind of moments that stay with you.
4.92 out of 5 average rating, 100 reviews
Quiet Country Home
Extremely clean home. Fenced private yard with Webber Genesis BBQ & Tables. Outdoor smoking. 25 minutes to beach or downtown. Rural area with animals “talking”. Horse visits and carrots included. Seasonal Fruits & Vegetables. 1st bedroom: king/full bath. 2nd bedroom: queen/work desk. 3rd bedroom: full & 2 twin trundle. All dishes/appliances. Crib & Highchair available Host lives in a separate complete 1 bedroom studio with a shared laundry room.
4.98 out of 5 average rating, 124 reviews
SDSU Beach Cottage
Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.
4.97 out of 5 average rating, 398 reviews
Beautiful 3,000 Sq Ft Tropical Oasis
Beautiful 4 Bedroom, 2 1/2 Bath Family Home Located in Tranquil Fletcher Hills. This 3,000 sq. ft. Home is Perfect for large families who wish to Relax in a Peaceful Setting. 24-hour self check-in keypad after 4pm and check-out at 11AM. Host does not allow parties/events. This is NOT a Party House! This home is located in a quiet residential neighborhood, Guests who do not respect this will be asked to leave.
4.96 out of 5 average rating, 178 reviews
Spacious & Fun | 5br, 4.5ba | Hot Tub | Views
Experience sunny San Diego from this 5 bedroom, 4.5 bathroom foothill home. Wake up to panoramic views of the surrounding hillsides and gather in the spacious living and dining rooms. The home is conveniently located just 15-20 minutes from San Diego's famous beaches and top attractions. After a day of exploration, unwind in the backyard area featuring a hot tub, fire pit, pool table, and life-sized chessboard.
4.99 out of 5 average rating, 133 reviewsPopular amenities for Santee house rentals
House rentals with a pool

San Diego Pool | Fire Pit | Sunshine | Sleeps 10
4.85 out of 5 average rating, 263 reviews
Bright and spacious home with views, pool & spa.
4.87 out of 5 average rating, 239 reviews
Upscale Resort House /Views, Saltwater Pool/Spa !
4.96 out of 5 average rating, 227 reviews
Mid-Century Style Family House with Spa
4.99 out of 5 average rating, 205 reviews
QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus
4.9 out of 5 average rating, 113 reviews
Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
5.0 out of 5 average rating, 302 reviews
Tropical Oasis: spa, solar heated pool, waterslide
4.98 out of 5 average rating, 137 reviews
ModernCoastal I View I Pool ITub
4.98 out of 5 average rating, 116 reviewsWeekly house rentals

Dream Home Away From Home - Huge Common Area!
4.76 out of 5 average rating, 200 reviews
Hilltop Retreat with Hot Tub, Theater, and Views
4.89 out of 5 average rating, 206 reviews
Palm Cottage, San Diego
4.94 out of 5 average rating, 149 reviews
The Home with The View
4.98 out of 5 average rating, 105 reviews
Suite Charles Way: A Cozy Fletcher Hills Studio
4.98 out of 5 average rating, 160 reviews
The Glass House - A Nature Retreat
4.97 out of 5 average rating, 933 reviews
Sunnyside Resort Spa, Beach, Zoo, Arcade
4.89 out of 5 average rating, 142 reviews
Spacious home with incredible backyard views
4.92 out of 5 average rating, 479 reviewsPrivate house rentals

Panoramic lake view in Santee with a parking spot
4.69 out of 5 average rating, 29 reviews
Stunning Mountains view
4.81 out of 5 average rating, 27 reviews
Spacious 5BR Group Retreat w/ Backyard Lounge
4.85 out of 5 average rating, 26 reviews
The Sand House-Gorgeous 3BR-2B HotTub+FirePit+Turf
4.95 out of 5 average rating, 81 reviews
Relax in Lakeside.
4.98 out of 5 average rating, 42 reviews
Lime Light La Mesa New 4BR 3BA, Group Friendly
4.98 out of 5 average rating, 66 reviews
Coastal Charm Getaway!
4.95 out of 5 average rating, 78 reviews
SD Summer Oasis | Pool, Spa & Garden Views
5.0 out of 5 average rating, 35 reviewsWhen is the best time to visit Santee?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $213 CAD | $206 CAD | $252 CAD | $238 CAD | $229 CAD | $280 CAD | $306 CAD | $269 CAD | $243 CAD | $243 CAD | $267 CAD | $221 CAD |
| Avg. temp | 15 °C | 15 °C | 16 °C | 17 °C | 18 °C | 20 °C | 21 °C | 22 °C | 22 °C | 20 °C | 17 °C | 14 °C |
Destinations to explore
- San Diego Vacation rentals
- Los Angeles Vacation rentals
- Phoenix Vacation rentals
- Paradise Vacation rentals
- Scottsdale Vacation rentals
- Las Vegas Vacation rentals
- Big Bear Lake Vacation rentals
- Palm Springs Vacation rentals
- Tijuana Vacation rentals
- Joshua Tree Vacation rentals
- Long Beach Vacation rentals
- Santa Barbara Vacation rentals
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Pechanga Resort Casino
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
- Ocean Front Walk
- Anza-Borrego Desert State Park
- Oceanside City Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego





