
House vacation rentals in Santee
Find and book unique houses on Airbnb
Quick stats about house rentals in Santee

Total vacation rentals
Explore 50 vacation rentals in Santee

Nightly prices starting at
Santee vacation rentals start at $56 CAD per night before taxes and fees

Verified guest reviews
Over 1,440 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space and kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Vacation rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
50 of Santee vacation rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santee rentals

4.9 Average rating
Santee stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in Santee
Guests agree: these houses are highly rated for location, cleanliness, and more.

Family Fun! Game Garage + Big Yard + Free Parking
Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min
4.94 out of 5 average rating, 163 reviews
Fletcher Hills luxury, Sunset View, 4 BR, Pool/Spa
✨ Luxury Hillside Retreat | Private Entrance | Saltwater Pool & Spa Enjoy this luxuriously furnished 4-bedroom, 2-bath home in Fletcher Hills, CA, perched on a hill with stunning mountain and San Diego city views. Relax in your private saltwater pool and jacuzzi with color-changing LED lights, or unwind indoors with full kitchen access, high-speed Wi-Fi, and smart TVs with Netflix. Perfect for couples, business travelers, and families, this cozy yet elegant retreat makes you feel right at home.
4.94 out of 5 average rating, 156 reviews
San Diego Casita for 6 Morey de Prieto Surf Ranch
The Morey de Prieto Surf Ranch is truly awesome! Reserve your stay in this 2 Bed/1 Bath 650 sq. ft. casita for six. Home includes kitchen with GE electric cooktop, refrigerator, microwave/air fryer, rice cooker, mixer for drinks, sink with prep trays, Moen faucet fixtures, gorgeous shower, Krups coffee maker, 50" smart TV equipped with WiFi and NetFlix, mountain views, workspace and a sofa bed. Relax on s 240 sq. ft. private deck with fire pit, adirondack chairs and BBQ. Level 1 EV Charger.
4.93 out of 5 average rating, 151 reviews
5 Bed Zen Oasis | Fire Pit, BBQ, Laundry, Parking
Capture the essence of San Diego in our 3 bedroom house hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 10 guests with beautiful outdoors and garden, fire pit table, BBQ grill, FREE laundry, central A/C and heating, 5 comfortable king and queen size beds, plenty of sheets and towels, 4 large HDTVs, Netflix, Max, Hulu, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!
4.85 out of 5 average rating, 282 reviews
Mid-Century Style Family House with Spa
This home is the epitome of 1950’s luxury. A perfect family oasis, you won’t even want to leave the property. Beautiful Mt. Helix mid-century modern family home with incredible views, designed by architect of original Las Vegas Desert Inn situated on nearly an acre. Less than 20 minute drive to beaches/Zoo/Sea World/Downtown. With a swimming pool, jacuzzi, and AC. Surrounded by orange, lemon, pomegranate trees and herb garden. No loud parties please, this is a quiet community.
4.99 out of 5 average rating, 205 reviews
Your SD Home Away from Home-Big Family Retreat
Not just a stay—a space to belong. This 4BR San Diego retreat is designed for real connection, with room to breathe, soft touches throughout, and everything you need to feel at home from the moment you arrive. Laugh late into the night, greet sunlit mornings with coffee in the garden, and linger over unhurried meals. Become a local in one of San Diego’s safest, quietest neighborhoods—your home base for memory-making, firelit stories, and the kind of moments that stay with you.
4.92 out of 5 average rating, 100 reviews
Dream Home Away From Home - Huge Common Area!
Bring the whole family to this spacious 1904 square foot home with TWO king sized bed suites and three full bathrooms! Located centrally in San Diego, this is a perfect place to stay for those seeking an experience close to the beach and mountains and anywhere in San Diego you'd like to visit. The house is a short drive away from the zoo, Sea World, Animal Park, beaches, parks, downtown, trails, Balboa park, the Midway museum, Coronado, Torrey Pines, La Jolla Cove, and much more!
4.76 out of 5 average rating, 200 reviews
Palm Cottage, San Diego
Palm Cottage sits in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully remodeled and stylish interior featuring both Dutch & French doors letting in plenty of sunshine. A large private yard w/ covered outdoor living area creates the ultimate indoor/outdoor lifestyle. You're steps from the local grocery store, village shopping, coffee shops, restaurants, bars and the trolley. You could not ask for a better location!
4.94 out of 5 average rating, 149 reviews
Quiet Country Home
Extremely clean home. Fenced private yard with Webber Genesis BBQ & Tables. Outdoor smoking. 25 minutes to beach or downtown. Rural area with animals “talking”. Horse visits and carrots included. Seasonal Fruits & Vegetables. 1st bedroom: king/full bath. 2nd bedroom: queen/work desk. 3rd bedroom: full & 2 twin trundle. All dishes/appliances. Crib & Highchair available Host lives in a separate complete 1 bedroom studio with a shared laundry room.
4.98 out of 5 average rating, 124 reviews
SDSU Beach Cottage
Welcome to our charming SDSU Beach Cottage! Centrally located in a desirable San Diego neighborhood, you're just 10 minutes from many of the city's top attractions. Steps away, you'll find popular local dining, a wine bar, pub, natural market, pizza shop, nail salon, liquor store, and Einstein Bros. Bagels. Enjoy San Diego's best or unwind in our tropical backyard featuring outdoor games and ping pong. Minimum age to book: 25.
4.97 out of 5 average rating, 398 reviews
Beautiful 3,000 Sq Ft Tropical Oasis
Beautiful 4 Bedroom, 2 1/2 Bath Family Home Located in Tranquil Fletcher Hills. This 3,000 sq. ft. Home is Perfect for large families who wish to Relax in a Peaceful Setting. 24-hour self check-in keypad after 4pm and check-out at 11AM. Host does not allow parties/events. This is NOT a Party House! This home is located in a quiet residential neighborhood, Guests who do not respect this will be asked to leave.
4.96 out of 5 average rating, 178 reviews
Spacious & Fun | 5br, 4.5ba | Hot Tub | Views
Experience sunny San Diego from this 5 bedroom, 4.5 bathroom foothill home. Wake up to panoramic views of the surrounding hillsides and gather in the spacious living and dining rooms. The home is conveniently located just 15-20 minutes from San Diego's famous beaches and top attractions. After a day of exploration, unwind in the backyard area featuring a hot tub, fire pit, pool table, and life-sized chessboard.
4.99 out of 5 average rating, 133 reviewsPopular amenities for Santee house rentals
House rentals with a pool

San Diego Oasis- A Retro Retreat w/ King Size Bed!
4.92 out of 5 average rating, 102 reviews
Bright and spacious home with views, pool & spa.
4.87 out of 5 average rating, 239 reviews
San Diego Pool | Fire Pit | Sunshine | Sleeps 10
4.85 out of 5 average rating, 263 reviews
QUIET HOME -3 Bedroom & Den, + POOL, sleep 8 plus
4.9 out of 5 average rating, 114 reviews
Upscale Resort House /Views, Saltwater Pool/Spa !
4.96 out of 5 average rating, 227 reviews
San Diego Pool Retreat | Game Room • Sleeps 14
4.92 out of 5 average rating, 103 reviews
Jamul Hacienda | Couples Retreat | Pool & Views!
4.98 out of 5 average rating, 127 reviews
Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
5.0 out of 5 average rating, 302 reviewsWeekly house rentals

Zen Retreat: 3-Bedroom Oasis near La Mesa Village
4.96 out of 5 average rating, 143 reviews
Cozy 4bd Family Home near all SD Attractions!
4.85 out of 5 average rating, 427 reviews
Suite Charles Way: A Cozy Fletcher Hills Studio
4.98 out of 5 average rating, 160 reviews
Hilltop Retreat with Hot Tub, Theater, and Views
4.89 out of 5 average rating, 206 reviews
The San Diego Sunrise Abode
4.94 out of 5 average rating, 143 reviews
4 Bedrooms | Pool | Views | Games | Gym |
5.0 out of 5 average rating, 17 reviews
Modern Santee Getaway
4.91 out of 5 average rating, 45 reviews
Home In Santee
4.7 out of 5 average rating, 30 reviewsPrivate house rentals

Spacious 5BR Group Retreat w/ Backyard Lounge
4.85 out of 5 average rating, 26 reviews
SD Family Oasis | Pool, Spa & Garden Views
5.0 out of 5 average rating, 35 reviews
Lakeside Hilltop Retreat w/Amazing Pool & Spa
4.99 out of 5 average rating, 71 reviews
Quiet and convenient
4.72 out of 5 average rating, 85 reviews
Serene Lakeside Getaway-Sleeps 8
4.77 out of 5 average rating, 70 reviews
Spacious Home with Large Yard and Mountain Views
4.78 out of 5 average rating, 80 reviews
Relax in Lakeside.
4.98 out of 5 average rating, 42 reviews
Luxe Retreat•Pool•Spa•Game Room•Home Theater•Yoga
5.0 out of 5 average rating, 15 reviewsWhen is the best time to visit Santee?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $213 CAD | $206 CAD | $252 CAD | $238 CAD | $230 CAD | $280 CAD | $306 CAD | $269 CAD | $244 CAD | $244 CAD | $267 CAD | $221 CAD |
| Avg. temp | 15 °C | 15 °C | 16 °C | 17 °C | 18 °C | 20 °C | 21 °C | 22 °C | 22 °C | 20 °C | 17 °C | 14 °C |
Destinations to explore
- San Diego Vacation rentals
- Los Angeles Vacation rentals
- Phoenix Vacation rentals
- Paradise Vacation rentals
- Scottsdale Vacation rentals
- Las Vegas Vacation rentals
- Big Bear Lake Vacation rentals
- Palm Springs Vacation rentals
- Tijuana Vacation rentals
- Joshua Tree Vacation rentals
- Long Beach Vacation rentals
- Santa Barbara Vacation rentals
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- San Diego State University
- Balboa Park
- Tijuana Beach
- Pechanga Resort Casino
- Torrey Pines State Beach
- Mission Beach
- Las Olas Resort & Spa
- Ocean Front Walk
- Anza-Borrego Desert State Park
- Oceanside City Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego





