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House vacation rentals in Santee

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Top-rated house rentals in Santee

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favourite
A private yard showcases a small seating area with blue chairs under a large umbrella. Colorful flower beds line the space, with vibrant pink bougainvillea blooming nearby. Circular stepping stones lead through the natural ground, enhancing the outdoor setting.
Home in Emerald Hills
4.9 out of 5 average rating, 288 reviews

Snazzy Spot with yard near beaches and downtown

Welcome to this modern get-away that is as bright and cheerful as a sunny day! You'll be sure to be rejuvenated here after your trips to the nearest beach (only a 15 minute drive) and outings on the town (only 10 minutes by car to downtown). This spot includes a private parking spot and a private yard. Yours to enjoy are a very comfortable queen bed, TV in bedroom, Fast WiFi, and a well stocked kitchenette. There are also two canyon hikes within a 2 minute walk with views of downtown for sunset.

Top guest favourite
An outdoor seating area is equipped with sectional sofas arranged around a fire pit, featuring a grassy lawn surrounded by lush greenery. A large tree provides shade, while a spacious porch is visible in the background, contributing to the serene atmosphere.
Home in La Mesa
4.93 out of 5 average rating, 125 reviews

Family Fun! Game Garage + Big Yard + Free Parking

Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

Guest favourite
A contemporary casita is set against a vibrant sunset, showcasing large windows that reflect the warm colors of the sky. The entrance features a clear path leading to a well-lit doorway, surrounded by natural landscaping and scenic hillside views.
Home in Lakeside
4.94 out of 5 average rating, 112 reviews

SD Casita Sleeps 6 - Morey from Prieto Surf Ranch

The Morey de Prieto Surf Ranch is truly awesome! Reserve your stay in this 2 Bed/1 Bath 650 sq. ft. casita for six. Home includes a kitchen with many amenities including a GE electric cooktop, refrigerator, microwave and air fryer, rice cooker, Kitchenaid mixer, mixer for drinks, sink with prep trays, Moen faucet fixtures, gorgeous shower, Krups coffee maker, 50" smart TV equipped with WiFi and NetFlix, mountain views, workspace and a sofabed. How about a large deck with fire pit and BBQ?

Guest favourite
A spacious living area features a large leather sectional sofa positioned around a circular wooden coffee table. A wall-mounted TV is visible above a decorative fireplace, while natural light streams through a large window adorned with sheer curtains. A dining area is seen in the background.
Home in La Mesa
4.87 out of 5 average rating, 106 reviews

Sunny & Spacious 3BR Retreat w/ Parking & A/C

Centrally located in La Mesa is this newly refurbished home ideal for business or pleasure with all of life’s little luxuries waiting for you to enjoy. The home features open concept living with a gourmet kitchen, a chic dining space, 3 beautiful bedrooms, 2 modern bathrooms and an expansive yard with an outdoor lounge. Walk 10 mins to Grossman Center with a Target, restaurants, cafes, a cinema & Walmart or drive to the heart of San Diego and all its attractions just 20 mins from your door.

Top guest favourite
An open-concept living area is highlighted by high ceilings and large windows, offering natural light. A modern kitchen features wood cabinets and a white island, while a dining table with turquoise chairs accommodates several guests. A cozy seating area is visible in the background.
Home in Ramona
4.97 out of 5 average rating, 879 reviews

The Glass House - A Nature Retreat

Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

Guest favourite
A serene outdoor space features a salt-water pool surrounded by a concrete patio and manicured grass. An umbrella provides shade over the poolside area, with lush greenery and mountains visible in the background under a partly cloudy sky.
Home in Lake Murray
4.88 out of 5 average rating, 212 reviews

Bright and spacious home with views, pool & spa.

This beautiful and recently remodeled, open-floor plan home is conveniently located directly across from Cowles Mountain, one of San Diego's most visited hiking trails. Each bedroom has its own full bathroom. Perfectly located for the outdoorsy family. Tons of hiking and mountain bike trails are just across the street. Only 15 min. away from beaches, zoo, & Sea World. Gaslamp/Downtown is only 20 min. by car. After a day of exploring, come home to a newly-built, salt-water pool and spa.

Top guest favourite
A view into a modern living space reveals a sleek kitchen with bar seating and a spacious dining area. Natural light floods the room through large glass doors, showcasing lush greenery outside. A cozy area is completed with a colorful rug beneath and a inviting seating arrangement.
Home in La Mesa
4.94 out of 5 average rating, 233 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Top guest favourite
A colorful studio space features turquoise walls and a ceiling fan. A comfortable sofa with decorative pillows is paired with a coffee table. A bed with a floral-patterned comforter sits against a window, while a TV and white refrigerator complete the modern setup.
Home in La Mesa
4.98 out of 5 average rating, 301 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental!   Our studio is newly remodeled with luxury ammenities.  We proudly cater to the cannabis community and non-users alike.   Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest.  This ensures that every guest checks into a clean, fresh-smelling place that feels like home.   Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Top guest favourite
A comfortable living area features a large sectional sofa with decorative pillows. Natural light streams in through two windows, adorned with dark curtains. A rustic brick fireplace and a low wooden coffee table with magazines add character to the space, enhancing its welcoming ambiance.
Home in Rolando
4.93 out of 5 average rating, 148 reviews

(Relist!) Relax at a Stunning 1931 Historic Tudor!

Come & enjoy our 1931 historic tudor home! Beautifully rebuilt within the last 2 years. This house has a huge front lawn and space to roam. Enjoy the serenity this large property has to offer. Three peaceful patios to enjoy your morning coffee. The kitchen has an 48-inch 1950’s oven for the chef in the family. Bay windows, arched entryways and original light fixtures make this such a charming place to stay. Centrally located to enjoy everything San Diego & La Mesa has to offer.

Guest favourite
A cozy red-brick bungalow with a charming architectural style is highlighted by modern landscaping. The driveway leads to both the home and a garage, while a garden of greenery enhances the welcoming exterior. The home features large windows, inviting natural light into the living space.
Home in Talmadge
4.86 out of 5 average rating, 250 reviews

Cozy Bungalow

Light and bright, cozy and modern. This single family home is the perfect spot for a small family or couples traveling together. Tastefully decorated and thoughtfully furnished; you'll feel right at home in this cozy Bungalow. Central location and easy access to major freeways makes getting around the city a breeze. Within 1 mile to San Diego State University, 15 minutes to multiple beaches, Gaslamp, Balboa Park, Mission Bay, and many other local attractions.

Guest favourite
Home in College East
4.91 out of 5 average rating, 141 reviews

Cozy Cottage | Walk to SDSU | Free Laundry

Perfect Space for a Couples Staycation! ☀ Spacious, modern, and beautifully designed property ☀ Prime location near public transportation, top restaurants, shops, and attractions ☀ Fully furnished with all the essentials for ultimate comfort ☀ Enjoy year-round comfort with air conditioning and heating ☀ Stay connected with high-speed internet, perfect for work or streaming ☀ Only 25 minutes from San Diego International Airport!

Guest favourite
An open living area features a large wooden dining table surrounded by six white chairs. A cozy sofa, adorned with neutral pillows and a blanket, overlooks expansive glass windows showcasing hillside views. A Christmas tree stands in the corner, adding a festive touch.
Home in Bonita
4.91 out of 5 average rating, 363 reviews

Glass Home with Views, Hot Tub, FREE EV Charging!

Update: We just installed a level 2 EV charger and are giving away free EV charging to the next 5 guests! Our modern, light-filled, scandinavian inspired home is a beautiful place to rest while you enjoy the magic of San Diego. The entire front of our home is glass with breathtaking views over the mountains and reservoir below. Neutral decor and warm wood accents provide a relaxing atmosphere and a tranquil setting.

Popular amenities for Santee house rentals

When is the best time to visit Santee?

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Quick stats about house rentals in Santee

  • Total vacation rentals

    Explore 50 vacation rentals in Santee

  • Nightly prices starting at

    Santee vacation rentals start at $41 CAD per night before taxes and fees

  • Verified guest reviews

    Over 1,390 verified reviews to help you choose

  • Family-friendly vacation rentals

    30 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wifi availability

    50 of Santee vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santee rentals

  • 4.9 Average rating

    Santee stays are highly rated by guests—averaging 4.9 out of 5!

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