Vacation rentals in Cambridge

Downtown apt. 8

I bedroom apartment in historic downtown building. 2 blocks from Knox College; 3 blocks from Amtrak Station. Several good restaurants and bars nearby; downtown Y a block away. 12' ceilings, hardwood floors, full kitchen and bathroom, coin laundry down the hall. Heat from radiators. Window AC units in summer. TV in bedroom. (For some reason, the listing says 4 beds; that is incorrect.) The apt. is on the 2nd floor: 26 steps. (No elevator.) Parking in lot across the street. Host lives nearby.

Dana's Retreat-glamping/camping @ a WildlifeRescue

Reconnect with nature at this unforgettable escape. Located at 2nd Hand Ranch & Rescue, this tiny house in the timber was built to share the beauty of nature with folks that want to camp.... but not really camp. This 12x12 house is off grid with a cute outhouse nestled in the timber behind the wildlife rescue. Relax and unplug for the weekend and know 100% of the fee goes to the animal rescue. We bring your supplies up via Gator as you hike the trail up. PLEASE NOTE: NO RUNNING WATER/SHOWERS

Mississippi River House

Now is a great time to stay in this completely furnished two-bedroom house directly overlooking the Mississippi River. The hot tub is amazing during the day and under the stars this time of year. Eagle watching in the winter is always entertaining while relaxing in the hot tub. This 1+ acre property is tucked away on a private dead end street, yet close to many great restaurants and shopping. If you're looking for a romantic getaway this house has everything you need for a wonderful time!

Aire Leclaire 2-bedroom home

Your family will be close to everything when you stay at Aire Leclaire! Within walking distance from downtown and 2 blocks from American Pickers. This modern 2 bedroom, 1 bath home is a block away from the tugfest parade route. A barnyard turned farmhouse in the 1940’s, this home completely remodeled with the modern farm charm it has today. In town for a day or several, enjoy outdoor amenities, a lighted deck, outdoor couch, and table. Inside, a modern LED fireplace mixed with rustic beauty.

Private & Modern. Near river and wildlife refuge!

Experience the outdoors in comfort from this modern cabin, situated next to the 2200 acre Princeton Wildlife Management Area, and the nearby Mississippi River. It is ranked as the most “Wish Listed” Iowa listing of 2025 on Airbnb. Are you into hiking, biking, fishing, hunting, boating, or other water, winter, and summer sports? This cabin can support it all! Sit back and relax on the large deck while enjoying a coffee & the local wildlife, flora, & fauna of the Mississippi Valley Region.

Enjoy the Rock River this Summer! Private!

Kick back and relax in this calm, stylish space. Located on the beautiful Rock River, this little cabin has all new interior and exterior. The 2 room studio is about 700 sq feet boasting a Murphy Queen bed and futon bed that converts to a twin/double. Everything has been updated with new appliances and washer and dryer. Beautiful walk in shower. Bay window facing the south overlooking the Rock River. 2 brand new decks, and you're only 1 block from the John Deere Golf Course

Laten Lodge

Experience Small-Town Living at Its Best… You’re just a short walk from the town park, local restaurants, bars, a charming ice cream shop, and a cozy coffee shop. Outdoor enthusiasts will appreciate the Rock Island Trail, which starts on the east side of town and stretches all the way to Peoria, Illinois—great for walking, running, or biking. Whether you’re here for a weekend escape or an extended stay, you’re sure to enjoy everything this small-town gem has to offer.

Rock River Escape

Enjoy your coffee, a nice bbq dinner, glass of wine, a good book, or just enjoy the sweeping views out of this cute bungalow. With 180 ft of unobstructed river views and river access, bring your fishing poles and get ready to relax and enjoy watching the water slowly drift by at this centrally located bungalow in a quiet residential neighborhood. Firepit with firewood provided. No parties allowed so please do not inquire about them.

The Cambridge House Hotel

The Cambridge House Hotel has been in active service as the the Cambridge Lutheran Church Parsonage for over 100 years.. and now you can stay in this magnificent House. Enjoy the front row seats to the Cambridge Lutheran Church Bell Carillon twice per day. Forget your worries in this spacious and serene space. Corporate rate is an additional $50/night. This property is strictly no-smoking/no-vaping.

Little House in Kewanee

Lovely Farmhouse Style 2 bedroom home located across from park. Newly decorated with fully equipped country style kitchen. The master bedroom has adjustable queen size bed while second bedroom has 2 twin beds. The house is great for a family, two couples or a girls weekend to Historic Bishop Hill or destinations Psycho Silo, Goods Furniture or Horse shoes at Blackhawk College East.

The Little Gem

Kick back and relax in this calm, stylish space. We have 1 bedroom with a queen bed, smart TVs and USB charging lamps. Feel free to prepare a meal in our stocked kitchen or prepare yourself a cup of coffee. This location is right off the Avenue of the Cities and is near grocery stores, restaurants and gas stations.

Lilla Vita Guest House, Historic Bishop Hill

Explore historic Bishop Hill then get some rest and relaxation in our newly remodeled guest house. Ideal for 1-4 guests. Within walking distance to several quaint shops, museums and restaurants. In an effort to keep ourselves and everyone else healthy, we are currently booking only weekends with a 2-day minimum.