Vacation rentals in Clayton County

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Top-rated vacation rentals in Clayton County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
A quaint blue house is shown from the side, surrounded by lush green grass. A wooden fence partially outlines the property, with a few flowering plants positioned along the edge. Clear skies and sunlight illuminate the exterior, highlighting its welcoming presence.
Home in Prairie du Chien
4.98 out of 5 average rating, 161 reviews

Ohio Street Retreat- hot tub, massage chair, pool

After a fun day in The Driftless Area, come relax and unwind in Prairie du Chien. Beautifully decorated 2 bedroom home with a spacious kitchen, large island, dishwasher, washer/dryer & 5' walk in shower. We supply all cooking/baking items/utensils. High-speed internet with smart TVs in both bedrooms and living room. Outdoor pool (seasonal), hot tub and massage chair. We love dogs too, so we provide a dog run (there is a pet fee). For our fishermen- there is off street parking for your boats.

Superhost
A welcoming kitchen area features wooden cabinetry and stainless steel appliances, with warm lighting illuminating the space. A small dining table with two stools is positioned nearby. The floor showcases light wood planks, complemented by a patterned black and white rug.
Home in Guttenberg
5 out of 5 average rating, 4 reviews

Hooks & Honkers Hideout

Welcome to Hooks and Honkers Hideout - your cozy riverside retreat tucked along the beautiful Mississippi River. This 2-bedroom getaway is perfect for couples or small groups looking to unwind, cast a line, or gear up for a duck hunt. Wake up to misty mornings, sip coffee with bluff views, and spend your day fishing the legendary waters or exploring the surrounding wild. After the hunt or a day on the river, come back to a warm and peaceful space where you can relax, recharge, and reconnect!

Top guest favourite
A clear drink adorned with lemon slices and colorful ice cubes rests on a wooden deck railing. In the background, the tranquil waters of the Mississippi River reflect the sky, framed by lush trees and a peaceful shoreline.
Home in Cassville
4.84 out of 5 average rating, 120 reviews

Right on the Mississippi...relax and enjoy!

Our little spot is right on the mighty Mississippi river, a beautiful spot to relax, fish, bird watch including eagles! We feature a large deck facing the water to enjoy morning coffee or an evening cocktail to watch sunsets. When you’re ready to settle in for the evening, we have ready-to-cook kitchen, grill, WiFi, Amazon Prime and Netflix, fireplace and comfy seating. So just relax! Small Wisconsin town with BIG relaxation. See more in this video! https://youtu.be/rM2HnmNMu4U

Top guest favourite
Apartment in Clayton
4.91 out of 5 average rating, 23 reviews

River View Upstairs Apartment in Clayton

Come visit the small river town of Clayton! Enjoy the stunning views of the Mississippi River where you will see boat traffic and barges running daily throughout the summer. There are two great restaurants in town open Thursday through Sunday that serve fish, shrimp, steak, burgers, and more. There is a local park just around the corner, and also docks available for fishing. Northeast Iowa has plenty to offer during your stay such as hiking, fishing, shopping, food, wineries, and more.

Top guest favourite
Two kayaks, one red and one blue, are parked on a sandy shoreline beside a tranquil pond. Two white lounge chairs are positioned for relaxing near the water's edge, with lush greenery and trees in the background under a partly cloudy sky.
Tiny homes in Monona
4.94 out of 5 average rating, 207 reviews

Creekside-water and nature lovers paradise

Is this Heaven? Maybe. Are you looking for a fun getaway for yourself, family, or friends? Well, look no further. Our place is ready for you to make lifelong memories. Create and tell stories while sitting under the stars next to the crackling campfire. Do your morning yoga by the babbling stream. Hike the trails. Soak up the sun on the sandy beach while listening to the waterfall. Laugh and splash your kiddos in our pond. Beach chairs, sand toys, floaties, kayaks, and more.

Top guest favourite
A lush green landscape rises just beyond a calm river, with a small collection of buildings visible along the shore. The architecture varies, featuring both traditional and modern designs, under a sky filled with fluffy clouds.
Apartment in Clayton
4.93 out of 5 average rating, 166 reviews

Cozy Apartment Steps from the Mighty Mississippi

Disconnect from the daily grind and enjoy a getaway in this welcoming one bedroom apartment, steps away from the Mighty Mississippi. Located in Clayton, Iowa, Located within walking distance of two delicious restaurants and a boat launch., and only 1/2 hour from the Casino Queen, local wineries, Pikes Peak State Park, as well as the historic communities of Elkader, IA and Prairie Du Chien, WI. Need more space? I also offer a two bedroom apartment: www. airbnb. com/rooms/43979345

Superhost
A scenic view features the mighty Mississippi River alongside wooded hills adorned with autumn colors. A playground is visible in the foreground, bordered by trees. The image captures a clear sky with hints of morning light reflecting on the water.
Apartment in Guttenberg
4.81 out of 5 average rating, 182 reviews

Dam River Penthouse

The Penthouse is on the 3rd floor of 308 S. River Park Dr., across from Guttenberg's Lock & Dam #10. Enjoy River Side Park across the street, walking trails along the Great Mississippi River, rolling hills, open highways, outdoor recreational opportunities. Such as; boating, ice- fishing, eagle watching, hiking trails throughout North East Iowa; Pikes Peak Sate Park located in McGregor, Iowa~27 miles from Guttenberg, Effigy Mounds National Monument about 2 miles from McGregor.

Guest favourite
A vibrant orange cabin is set against a backdrop of trees and gentle hills. Large windows and a front door reveal a welcoming appearance. A winding gravel path leads to the entrance, surrounded by lush green landscaping and natural foliage.
Cabin in Bagley
4.89 out of 5 average rating, 223 reviews

**Cozy & Dog Friendly** Rustic Cabin Retreat

Relax and recharge at this country getaway which is tucked amongst trees and the rolling hills. Surround yourself with nature while also having easy in and out access! This makes it a breeze to come and go as you please and explore all southwest Wisconsin has to offer! Ready for the whole family to enjoy, along with their furry friends. *9 minute drive to Wyalusing State Park *10 minute drive to Bagley / Wyalusing Public Beach *16 minute drive to Prairie du Chien

Superhost
A fire pit surrounded by green adirondack chairs is positioned on a gravel area, with a view of the Mississippi River in the background. Large trees provide shaded spots, and additional seating is visible near the water.
Tiny homes in McGregor
4.79 out of 5 average rating, 130 reviews

The Cottage

A Quaint Cottage on the Mississippi River one mile north of Marquette, IA. One bedroom with additional sofa sleeper in the common area. Public boat landing, Casino and Winery all within one mile. Gas grill and fire pit on site. Effigy Mounds and Pikes Peak within 3 miles. Prairie du Chien just across the bridge. Great eating and shopping in nearby McGregor! Fun family getaway or great area for fishermen! Seasonal cottage books May thru Mid October.

Top guest favourite
A charming exterior view of a gray cottage features a red convertible parked in front. The building is labeled with the word 'Cozy,' and a large tree provides some shade. The overall setting reflects a welcoming environment, ideal for relaxation.
Tiny homes in Marquette
5 out of 5 average rating, 78 reviews

Cozy Casita

A peaceful little place to rest and refresh while visiting family and friends or exploring the driftless region of NE Iowa and SW Wisconsin. Nestled in the bluffs on the western bank of the Mississippi you'll be only a couple minutes from the bridge to Prairie du Chien and all the other places of interest up and down both sides of the river; including Pikes Peak State Park, Effigy Mounds, Wyalusing State Park and Cabela's just to name a few.

Top guest favourite
The exterior of the 1884 Red Brick Cottage is shown, featuring a classic brick facade and a welcoming front porch with a screened area. Lush green lawns surround the property, with a driveway leading to the house. Scenic hills are visible in the background.
Home in Marquette
4.96 out of 5 average rating, 201 reviews

1884 Red Brick Cottage

Step back in time to a quiet small town in Iowa, nestled within the hills of the driftless area. Time seems to stand still while you're here. The 1884 Red Brick Cottage offers 3+ Bedrooms in a peaceful neighborhood, close to riverfront activities, casino and downtown Marquette. Spacious backyard and sideyard, house is fully furnished and includes a firepit and gas grill for evening outdoor activities.

Guest favourite
Home in Guttenberg
5 out of 5 average rating, 15 reviews

Secluded Bardo Retreat w/ Hot Tub + View

Find Your Stillness | Omega Ridge Retreat on 6 Private Acres This one-of-a-kind property features a brand new Barndominium, perfect for couples’ getaways, family gatherings, small retreats, or anyone longing to unwind in nature without sacrificing comfort. This area is great for hiking hunting fishing, canoeing side-by-side riding & near the historic town of Guttenberg just 6 miles away.

Popular amenities for Clayton County vacation rentals

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  3. Iowa
  4. Clayton County