Vacation rentals in Clayton

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Top-rated vacation rentals in Clayton

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favourite
A living area features a comfortable gray sofa and two red accent chairs, inviting relaxation. A coffee table sits in the center, complemented by a soft area rug. Natural light filters through a window, covered by light curtains, enhancing the cozy atmosphere.
Condo in University City
4.91 out of 5 average rating, 317 reviews

Modern Condo on Delmar Loop; Central to Everything

This absolutely stunning condo in the Delmar Loop are has everything you could need. Located only 100 feet from Delmar and a short walk to WashU Campus or Forest Park. Metro Link is only a 10 minute walk away. Perfect for visits to WashU for college visits and graduations! The Pageant and Delmar Hall making this the perfect condo to stay in to see your favorite band! One off-street parking spot in a gated parking lot. The entire condo community is gated & equipped with video surveillance.

Top guest favourite
A light-filled living room features a comfortable sofa adorned with decorative pillows, complemented by two yellow accent chairs. A glass coffee table sits atop a textured rug, with natural light entering through windows dressed with blinds. The open layout leads to a dining area in the background.
Home in Dogtown
4.99 out of 5 average rating, 161 reviews

Dogtown Century home near Forest Park & Maplewood

Our historic home has lots of natural light and high ceilings. The two bedrooms are furnished with comfy queen beds. The sunroom also doubles as a third sleeping room. Enjoy a morning cup of coffee on the large front porch, or yard games and bbq in the fenced back yard. The updated kitchen comes fully equipped with everything you need to help you feel right at home. Minutes from Forest Park, BJC and SSM hospitals, universities, downtown, many great restaurants and shops. Furry friends welcome!

Top guest favourite
The exterior of a historic two-family brick home is visible, featuring a spacious front porch with seating and a vibrant red door. Lush greenery and landscaped bushes frame the steps leading to the entrance, while neighboring buildings exhibit classic architectural style.
Apartment in West End
4.94 out of 5 average rating, 583 reviews

3-bdrm apt near Pageant, Wash U, Forest Park, Loop

Three bdrm, top floor apt. with private entrance in our home. Roomy, comfy, well-furnished with everything you need. Walk to Pageant, Delmar Hall, WashU, Blueberry Hill, Salt&Smoke, MagicMiniGolf. CVS, grocery, restaurants and shops on the Delmar Loop. Or stroll our leafy streets to Forest Park, built 1904 for a World’s Fair, now a first-class museum, zoo, golf course, boat rental. Easy access via metro train or Uber/Lyft to airport, baseball, hockey, live music clubs, City Museum, the Arch.

Guest favourite
A spacious bathroom features a freestanding bathtub surrounded by natural stone walls. A walk-in shower with a glass panel is visible alongside a modern sink. Warm lighting hangs above, and a potted plant adds a touch of greenery, enhancing the serene atmosphere.
Home in St. Louis
4.92 out of 5 average rating, 150 reviews

Tranquil three-bedroom home in central St. Louis

Welcome to Spa 7748! Relax and enjoy the quiet, tranquil space we have to offer you. Three bedrooms, two full baths, laundry room, work out area, media/office area, fully equipped chef’s kitchen, two fireplaces, covered patio, outdoor fire pit, driveway parking, and street parking. Centrally located in University City, which is just minutes from the downtown Clayton business/entertainment district, Washington University, Fontbonne University Downtown STL, Central West End, The Grove, Dogtown.

Guest favourite
A cozy living room is highlighted by a vintage-style mirror and decorative fireplace. Comfortable seating, including a golden armchair, is arranged around a central coffee table. Large windows allow natural light to flow in, complemented by patterned curtains and a detailed area rug.
Apartment in Southwest Garden
4.93 out of 5 average rating, 376 reviews

Historic Victorian comfort, safe central apt

First, check out all 4 of our private 5 Star listings that creatively combines the old with the new. If one is unavailable, check the others by going to “My Profile” and scrolling down until you see all 4. This Historic building; built in 1896 has changed missions through the years; From church, to merc. Trade, to grocery store; quite the history have graced these walls. You’ll love our safe, Southwest Gardens area; next to the famous “Hill” offers unmatched restaurant, shops, bakeries

Guest favourite
A charming brick bungalow is framed by a vibrant garden filled with colorful flowers and lush greenery. A stone pathway leads to the entrance, bordered by various plants. Natural light illuminates the area, showcasing the home's inviting exterior.
Home in St. Louis
4.92 out of 5 average rating, 450 reviews

Charming Cottage Near Forest Park in Quiet Area

Welcome to our home! It is a cozy brick bungalow from 1929. It is a quiet neighborhood. Partially fenced backyard. We're located close to historic Route 66, coffee shops, shops, restaurants. 15 minute drive from Gateway Arch National Park, Busch Stadium, Forest Park, Enterprise Center, Washington University, St. Louis University, Zoo, Art Museum, and Botanical Gardens. Smoking is not allowed inside or outside. Any smoke odor will result in a $150 fine. Noise monitoring device on property.

Guest favourite
A modern living area features a blue sofa facing a large flat-screen TV. A marble coffee table rests on a patterned rug, with a tall indoor plant adding a touch of greenery. Natural light enhances the space through multiple large windows.
Apartment in Central West End
4.89 out of 5 average rating, 151 reviews

1 BR Loft Near Central West End, Walk to BJC

Welcome to loft luxury, walking distance to BJC, nightlife, metro station, & Whole Foods! This space includes garage parking, in-unit W/D, and everything to stay a night or a month! Other great features: - High ceilings & huge windows - Pullout couch - 55" TV - Workspace w/ fast wireless internet - Fully-equipped kitchen - Queen memory foam bed *Please note, this loft's bedroom walls don't extend to the ceiling & there is no door. Please check photos to ensure the space meets your needs!

Top guest favourite
A well-furnished room features a spacious bed with accent pillows and a comfortable seating area. A TV is mounted on the wall opposite the bed, and ample natural light enters through multiple windows adorned with sheer curtains. Decorative elements contribute to a cozy ambiance.
Tiny homes in Shaw Historic District
4.98 out of 5 average rating, 618 reviews

The Rabbit Hole

A beautifully decorated 450 sq ft space with Douglas fir bead board ceiling, fully functioning kitchen with gas range/oven and fridge; 50 inch TV that swivels 180 degrees for viewing in bed, common area and kitchen. Located across the street from Tower Grove Park (great for a morning run) & 2 blocks from the Mo Botanical Gardens. Located in the Historic Shaw neighborhood and within 5 miles of almost every major Saint Louis tourist attraction including downtown Saint Louis. Private patio

Superhost
The modern home features a spacious wooden deck with steps leading to a well-maintained garden. Large glass doors dominate the front facade, allowing natural light to flood the interior. Lush trees provide a serene backdrop, complementing the inviting outdoor space.
Home in Caseyville
4.87 out of 5 average rating, 126 reviews

Wooded Oasis with Free Bottle of wine+brkfst

Enjoy serenity and tranquility at our modern home tucked away in a private setting just 5 short minutes from Downtown St Louis. Complementary bottled water, continental breakfast(packaged muffins) and a bottle wine will pamper you the moment you arrive.Unwind in our luxurious multifunction shower+memory foam mattress Test your swing on our scenic driving mat or unwind around the crackling outdoor fire pit. Spa and Special Occassion add-on packages available. Private off street parking.

Top guest favourite
The exterior showcases a charming brick façade with arched entryways and decorative balcony. Vibrant flower boxes adorn the windows, while a variety of landscaping, including flowering plants and large stones, enhances the inviting entrance.
Home in Richmond Heights
4.99 out of 5 average rating, 186 reviews

ZOO, Wash U, close to Clayton,Parking & Safe!

This completely rehabbed light and airy home is located one mile from the World Famous Forest Park Zoo, Washington University and conveniently located to Highway 64/40. Enjoy a ten minute commute to downtown or Clayton, MO. Take advantage of walking to local restaurants, theaters, parks and grocery stores. This home is the perfect get away for family vacations, graduations and local events. Convenient off street parking, full kitchen and laundry available. Very safe neighborhood!

Top guest favourite
Home in St. Louis
4.96 out of 5 average rating, 181 reviews

Great Fam Friendly Home w/ Lrg Deck & Yard

**FAMILY FRIENDLY** (See details for the items avail for families) This 2 bedroom home has everything you need for a relaxing trip! Fully updated with stylish and comfortable furniture and decor. Fully equipped kitchen and an amazing backyard/deck. Quiet street by one of the best Mexican restaurants in St. Louis - Hacienda - (can walk 2 min there) Close to everything! 13 minutes to the St. Louis Zoo 10 minutes to The Magic House 15 minutes to Busch Stadium & Union Station

Top guest favourite
An outdoor living space features a spacious flagstone patio surrounded by lush greenery. A wooden picnic table sits center stage, complemented by vibrant flower planters. Adjacent to the house, double doors offer access to the interior, framed by an inviting pergola.
Home in Lindenwood Park
4.98 out of 5 average rating, 294 reviews

1902 House & Garden *Safe Private parking !

Welcome! We lovingly restored our beautiful 1902 home to reflect the period in which it was built. By incorporating modern comforts & functionality we created a truly unique stay! Interior is spacious & inviting. Our home boasts a gorgeous outdoor living space to relax and feel miles away from the city , yet we are perfectly situated to arrive at all of STL attractions within minutes. Location is near all major hwys. Note: we aren’t a place to entertain. Booked guests only.

Popular amenities for Clayton vacation rentals

When is the best time to visit Clayton?

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Frequently Asked Questions

  • Are there family-friendly vacation rentals in Clayton?

    Clayton has more than 10 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in apartment rentals in Clayton?

    Experience the best of Clayton with our apartment rentals, starting at about $60 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in Clayton?

    Four-legged friends are welcome in Clayton. Choose from more than 10 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in Clayton?

    Yes! Work meets play with ease at over 20 vacation rentals in Clayton featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Where should I stay in Clayton?

    Make yourself at home in Clayton by choosing from our most frequently booked neighborhoods. We have over 310 vacation rentals in Downtown Clayton, over 310 vacation rentals in Wydown Skinker, and over 540 vacation rentals in Clayton.

  • Do hotel rentals in Clayton have air conditioning?

    Absolutely! We offer over 10 hotel rentals with air conditioning in Clayton. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in Clayton have a kitchen?

    Absolutely! We offer over 20 apartment rentals with a kitchen in Clayton. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in Clayton have wifi?

    Absolutely! We offer over 20 apartment rentals with wifi in Clayton. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in Clayton have free parking?

    Absolutely! We offer over 10 apartment rentals with free parking in Clayton. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for Apartment Rentals in Clayton?

    Enhance your stay in our Apartment Rentals with the most popular amenities: over 20 homes with a kitchen, over 10 homes with free parking, over 20 homes with wifi, over 20 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

Quick stats about vacation rentals in Clayton

  • Total vacation rentals

    Explore 40 vacation rentals in Clayton

  • Nightly prices starting at

    Clayton vacation rentals start at $82 CAD per night before taxes and fees

  • Verified guest reviews

    Over 1,300 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space and kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wifi availability

    30 of Clayton vacation rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Clayton rentals

  • 4.7 Average rating

    Clayton stays receive an average rating of 4.7 out of 5 from guests

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