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Vacation rentals in Defiance

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Top-rated vacation rentals in Defiance

Guests agree: these stays are highly rated for location, cleanliness, and more.

Tiny homes in Pacific
Route 66 railroad shanty, a cozy artsy small space
This 536 s.f. house, believed to have once been a sleeping shanty for railroad crews switching shifts for the night. Fully renovated and updated in 2021 by a local artist, you will find custom metal art throughout, granite countertops and a very warm cabin feel featuring a kitchen and bathroom finished with locally sourced Missouri dark red cedar, 10 minutes from six flags, Purina farms 15 min from hidden valley and 45 min from downtown this place is in a great location and will not disappoint!
Home in Augusta
Katy Trail Farmhouse - 3 bd/2.5 bath - Amazing!
DIRECTLY ON THE KATY TRAIL! Quaint 1943 farmhouse on 7 private acres in Missouri wine country - halfway between Klondike Park & the town of Augusta. Loads of farmhouse charm w/ the amenities & comforts of home. Spacious & well-appointed, 3 bedrms/2.5 baths. Walk-in/out or bike-in/out to KATY trail -- the location is perfect. Enjoy a sunset dinner & live music at one of the many wineries – or relax on one of the two screened-in porches & clear your mind. No other place like it in Augusta!
Tiny homes in Pacific
Route 66 Cozy Cottage
* Fast Wifi (Spectrum) * Keypad entry (no keys to keep track of) * Private driveway by the front door for easy access to carry luggage in and out * Huge yard for dogs, kids or even adults to play * Lovely outdoor patio with plenty of comfortable seating and beautiful landscaping * For the kiddos- fun, colorful plastic dinnerware, toys, books, puzzles, and games (puzzles and games for adults too) * Essentials for your furbabies as well - treats, leashes, food & water bowls, waste bags, towels

Stay near Defiance's top sights

August A. Busch. Memorial Conservation Area4 locals recommend
Weldon Spring Conservation Area3 locals recommend
Chandler Hill Vineyards15 locals recommend
Historic Daniel Boone Home15 locals recommend
Defiance Roadhouse3 locals recommend
Wine Country Gardens11 locals recommend

Other great vacation rentals in Defiance

Farm stay in Lake Saint Louis
Updated Farmhouse 2 bd 2 acres
Farm stay in Grafton
Pere Ridge Tree Escape
Apartment in Washington
Elbert haus
Guest suite in Washington
The Roettger Inn Loft on the Riverfront
Home in Saint Charles
Bright & Cozy Shotgun 1 Block from Historic DT.
Apartment in Saint Charles
Christmas Getaway in Historic Old St Charles Pops
Home in Saint Charles
301 Guesthouse/SuperHost/Fast WiFi/Katy Trail/
Home in St. Louis
Sunny South City Guest House
Cottage in Saint Charles
The Rose Cottage -a short walk to Historic Main St
Tiny homes in Gray Summit
Sherry’s Shouse! 1 mile-Purina, Pet’s stay Free!
Home in Washington
The Tiny House
Home in Gray Summit
Pet Friendly - Fenced Yard - <1 mile from Purina

Destinations to explore

  1. Airbnb
  2. United States
  3. Missouri
  4. St. Charles County
  5. Defiance