Pet-friendly vacation rentals in Florence County

Find and book unique pet-friendly homes on Airbnb

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Popular amenities for Florence County pet-friendly home rentals

Pet-friendly house rentals

Guest favourite
Home in Florence
4.92 out of 5 average rating, 37 reviews

Collins Quarters

ErinRating, 5 stars3 weeks ago
Ashleys house is very unique and cool. The space was very clean and quiet neighborhood. Host was very responsive and plenty of spots nearby for food or other shoping needs.
Top guest favourite
Home in Florence
5 out of 5 average rating, 13 reviews

Quiet, Clean & Spacious 3bd near I-95 & Hospital

AnnetiaRating, 5 stars6 days ago
Zay’s place was absolutely perfect for my family and me! It was super convenient since it was just a short drive from our relatives who live in town. The house really felt like a home away from home—honestly, it had the comfort of a hotel, but with the bonus of total privacy and no shared walls. Zay was also incredibly responsive and helpful when I had a little trouble connecting to the Wi-Fi (totally my fault!). The home was spotless and had all the modern amenities we could ask for. And the gym? Such a great bonus! We had a wonderful stay and would definitely come back!
Top guest favourite
Home in Florence
4.96 out of 5 average rating, 23 reviews

2b/1.5bath brand NEW townhouse Closed to MUSC

AmyRating, 5 stars1 month ago
Great stay and great hosts. Thank you!
Top guest favourite
Home in Florence
5 out of 5 average rating, 9 reviews

Charming and spacious 4-bd 2 full ba WiFi, AC

RosieRating, 5 stars1 week ago
Great house in the perfect location for what we needed. We'll definitely stay again!
Home in Florence
5 out of 5 average rating, 3 reviews

Cozy One Story Town House

CherylRating, 5 stars3 days ago
The place meet my expectations. It was just like the pictures. We were very comfortable. Our host was wonderful and so very helpful. He responded in a very timely manner. We enjoyed our stay.
Home in Timmonsville
4.75 out of 5 average rating, 4 reviews

Private Getaway on Smith Street

TyleemaRating, 5 stars4 months ago
This place was everything we was looking for and more for the holidays! Raye was very prompt with any questions we had, and accommodated us beyond measures! I would definitely stay here again, the place is just like the pictures. With way more space than you need, in a very secluded quiet area.
Home in Effingham
4.88 out of 5 average rating, 8 reviews

"The Great Escape!"

TimothyRating, 5 stars2 weeks ago
Enjoyed our stay at Hazel’s home. We had an issue pop up with the home that Hazel quickly resolved. We appreciated how engaged Hazel was with ensuring we enjoyed our stay. Hazel has a beautiful, charming home and we will aim to stay here again if we are in the Florence, SC area.
Superhost
Home in Florence
5 out of 5 average rating, 4 reviews

Newly Renovated/Near Hospitals

GeorgetteRating, 5 stars21 months ago
This house was lovely. The decor was warm and inviting with a modern farm house vibe. The kitchen was well stoked with utensils, good pots and pans and storage containers. There was a keurig + k cups, sugar and basic spices. All of the appliances worked well. The linens were pristine and comfy. We truly enjoyed our stay here and will definitely come back next time we are in the area.

Private, pet-friendly home rentals

Guest favourite
Guesthouse in Florence
4.93 out of 5 average rating, 822 reviews

The Cottage by the Pool: Close to Interstates

GinaRating, 5 stars1 week ago
This was our second time staying at Reeve’s place while on a road trip. Only a few minutes off of 95. My mom and I had our two dogs with us. The pool house is the perfect size for two people. Both the bed and pull out are super comfortable. We were able to keep the gates to the pool closed so that our dogs didn’t bother the house dogs - although they are very sweet and quiet pups! Will definitely stay again on our next drive down 95. Thanks for having us back!
Guest favourite
Cottage in Darlington
4.82 out of 5 average rating, 317 reviews

Darlington Farm House Near I-95 & Florence

David & LindaRating, 5 stars3 weeks ago
We had a very nice stay here! It was super clean and relaxing. We enjoyed hanging out in the living room after a long drive. It was a great midway point on our way back to Florida. It was only 9 minutes to restaurants and gas. Our dogs and son loved running around out back! This is a very charming Southern home set against all the wisteria in bloom. We would stay here again!
Top guest favourite
Farm stay in Timmonsville
4.95 out of 5 average rating, 621 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

RebaRating, 5 stars3 days ago
Fabulous stay, highly recommend as a stop over on an I95 roadtrip—far superior to a hotel. Our son was fascinated with the animals and loved feeding the goats and alpaca!
Top guest favourite
Place to stay in Effingham
4.97 out of 5 average rating, 131 reviews

Gated and Private Catholic Hermitage house

SabrinaRating, 5 stars6 days ago
We stay here twice a year for a week at a time, and this is our third year. Always a pleasure to stay here with our two dogs. Tile floors and throw rugs, great with dogs! Nice fenced in back yard and away from town. We enjoy staying here and visiting our family. Lorraine and Mike are the best hosts, and always happy to see them. I very much recommend the Hermitage.
Top guest favourite
Cottage in Timmonsville
4.97 out of 5 average rating, 936 reviews

*Cottage Near Florence and I-95*

JasonRating, 5 stars2 days ago
I loved my stay at this cottage. We had the need for accommodations on short notice and Wanda was so very kind and responsive. Upon arriving at the cottage we were welcomed with such a comforting and inviting feeling it almost reminded me of my childhood home. The place was very clean and well stocked. We loved the space and I look forward to coming back to the area for another stay in the future.
Guest favourite
Farm stay in Hemingway
4.95 out of 5 average rating, 197 reviews

Quiet farmhouse near the beach

DenysRating, 5 stars1 week ago
Fantastic stay for a family. Loved it!
Guest favourite
Home in Lake City
4.91 out of 5 average rating, 112 reviews

Peaceful country close to town.

SherAntonaeRating, 5 stars1 week ago
We enjoyed every moment of our stay! The home is absolutely beautiful and has everything that you could possibly think you’ll need! The instructions were clear and home was better than described! We appreciate the easy check in process, the beautiful scenery and the immediate responses from the host were top tier ! We would love to stay there again while in town! It was truly a pleasure and a beautiful experience all around! Thank you again for allowing use your home for our retreat this week !
Guest favourite
Apartment in Florence
4.9 out of 5 average rating, 100 reviews

Upper Kuker Carriage House-Downtown Near I95&20

SiomaraRating, 5 stars2 days ago
It's such a cozy and clean place, the host were so prompt in responding despite my last minute reservation. I also got a message after we had checked out that we left some medicine in the fridge! We were able to pick up since were still in the area, we were extremly grateful for that! Definitley booking if we're are around in the future!

Destinations to explore