Pet-friendly vacation rentals in Florence County

Find and book unique pet-friendly homes on Airbnb

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Popular amenities for Florence County pet-friendly home rentals

Pet-friendly house rentals

Guest favourite
Home in Florence
4.92 out of 5 average rating, 39 reviews

Collins Quarters

SamRating, 5 stars2 weeks ago
Unique spot, kids loved the stairs, thought they were in the movie labyrinth.
Top guest favourite
Home in Florence
5 out of 5 average rating, 16 reviews

Quiet, Clean & Spacious 4bd near I-95 & Hospital

Stephen J.Rating, 5 stars1 week ago
An incredibly well-equipped, modern, new, beautiful facility with all the necessary and desired accommodations and luxuries.
Top guest favourite
Home in Florence
4.96 out of 5 average rating, 24 reviews

2b/1.5bath brand NEW townhouse Closed to MUSC

ChristopherRating, 5 stars1 week ago
This is the 2nd time I have stayed at this location in Florence. The place is very clean, comfortable beds, clean bathroom, and very easy to get into. The location was perfect for our needs, close to stores, food, and Francis Marion University. Wempy is a great host and very repsonsive. He answers mail within minutes and is always helpful. I would stay here again for sure. Thank you for a great stay!
Top guest favourite
Home in Florence
5 out of 5 average rating, 11 reviews

Charming and spacious 4-bd 2 full ba WiFi, AC

TitfannyRating, 5 stars4 days ago
Place was as advertised, clean, free of clutter and simply felt like home.
Guest favourite
Home in Florence
5 out of 5 average rating, 5 reviews

Cozy One Story Town House

RakeiaRating, 5 stars4 days ago
Great space ....love the space and location will definitely be back. thanks for the awesome communication
Home in Timmonsville
4.75 out of 5 average rating, 4 reviews

Private Getaway on Smith Street

TyleemaRating, 5 stars5 months ago
This place was everything we was looking for and more for the holidays! Raye was very prompt with any questions we had, and accommodated us beyond measures! I would definitely stay here again, the place is just like the pictures. With way more space than you need, in a very secluded quiet area.
Home in Effingham
4.88 out of 5 average rating, 8 reviews

"The Great Escape!"

TimothyRating, 5 stars1 month ago
Enjoyed our stay at Hazel’s home. We had an issue pop up with the home that Hazel quickly resolved. We appreciated how engaged Hazel was with ensuring we enjoyed our stay. Hazel has a beautiful, charming home and we will aim to stay here again if we are in the Florence, SC area.
Superhost
Home in Florence
5 out of 5 average rating, 4 reviews

Newly Renovated/Near Hospitals

GeorgetteRating, 5 stars22 months ago
This house was lovely. The decor was warm and inviting with a modern farm house vibe. The kitchen was well stoked with utensils, good pots and pans and storage containers. There was a keurig + k cups, sugar and basic spices. All of the appliances worked well. The linens were pristine and comfy. We truly enjoyed our stay here and will definitely come back next time we are in the area.

Private, pet-friendly home rentals

Guest favourite
Guesthouse in Florence
4.93 out of 5 average rating, 828 reviews

The Cottage by the Pool: Close to Interstates

IvetteRating, 5 stars1 day ago
We had a wonderful stay at this quaint poolside cottage while driving from Pennsylvania to Florida with our four dogs. It was the perfect overnight stop—clean, fresh-smelling, and super comfortable. The bed, sheets, and pillows were high quality, and we appreciated the soft towels and well-stocked coffee bar. The fenced yard was a huge bonus for the pups, and the flowers around the property added such a charming touch. Communication with Reeves was seamless. We only wish we could’ve stayed longer!
Guest favourite
Cottage in Darlington
4.82 out of 5 average rating, 320 reviews

Darlington Farm House Near I-95 & Florence

CathyRating, 5 stars3 weeks ago
Charming home with very nice details that made us feel special and welcome. Home was very clean and comfortable.
Top guest favourite
Farm stay in Timmonsville
4.95 out of 5 average rating, 625 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

CrystalRating, 5 stars1 week ago
We had a wonderful night stay at the beautiful farm! They were so kind and it was awesome seeing Shannon working with the animals with a newborn! They were so kind, the fresh eggs were delicious and colorful, everything we needed was there, and the animals were great! Our daughter loved it and it was perfect place to stay with our dogs on our road trip as a quick stay.
Guest favourite
Home in Sellers
4.91 out of 5 average rating, 74 reviews

Spacious, Historic Home for 12 - Near Myrtle Beach

JeanneRating, 5 stars1 week ago
We had a lovely stay, in town for our son’s wedding in Timmonsville. The house was perfect for our family for four days and three nights. Great space to host all 9 of us. It was prefect for this. Loaded of fun!!!
Top guest favourite
Place to stay in Effingham
4.97 out of 5 average rating, 132 reviews

Gated and Private Catholic Hermitage house

RonaldRating, 5 stars1 week ago
We were traveling long distance with a small dog and wanted to give him a nice place to run around after the long car ride. This place was perfect and the owners are obviously animal lovers as evidenced by treats and food for animals in the kitchen and a very nice fenced area with a doggy care section stocked with bags and a disposal container along with pick up tools. The setting is so peaceful and rustic and it provided us with a very restful night’s sleep so we were able to tackle another long day of driving. The host, Lorraine, was wonderful to deal with very responsive. If we travel through this area again we will surely book this property again.
Top guest favourite
Cottage in Timmonsville
4.97 out of 5 average rating, 938 reviews

*Cottage Near Florence and I-95* 3 Bedrooms

DaveonRating, 5 stars4 days ago
I had a fantastic experience with this Airbnb! Everything was well organized, the host was incredibly welcoming and knowledgeable, and the activity itself exceeded my expectations. It was a perfect blend of local culture, fun, and learning. I would highly recommend this experience to anyone looking to add something unique and memorable to their trip. Can’t wait to book another one!
Guest favourite
Farm stay in Hemingway
4.95 out of 5 average rating, 199 reviews

Quiet farmhouse near the beach

SophiaRating, 5 stars1 week ago
Was peaceful and quiet, had a lot of fun walking the trails and finding shark teeth. If you’re looking for a place where you can relax and enjoy nature I would highly recommend.
Guest favourite
Home in Lake City
4.91 out of 5 average rating, 114 reviews

Peaceful country close to town.

RobertRating, 5 stars4 days ago
This was just a short drive from Lake City and had plenty of space for our family. We enjoyed the peaceful country setting.

Destinations to explore