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Vacation rentals in Mesilla

Find and book unique accommodations on Airbnb

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Popular amenities for Mesilla vacation rentals

Stay near Mesilla's top sights

La Posta De Mesilla46 locals recommend
D.H. Lescombes Winery & Bistro35 locals recommend
Double Eagle34 locals recommend
Andele Restaurant16 locals recommend
Spotted Dog Brewery10 locals recommend
Hacienda de Mesilla17 locals recommend

Other great vacation rentals in Mesilla

Top guest favourite
Home in Las Cruces
4.91 out of 5 average rating, 64 reviews

Sonoma House | Pet Friendly, Modern | Peloton

DanielRating, 5 stars3 weeks ago
Excellent host, super friendly and responsive! House was very clean, functional and in a great location, would definitely stay again!
Top guest favourite
Guesthouse in Las Cruces
4.97 out of 5 average rating, 89 reviews

Southwest Escape

ErinRating, 5 stars1 week ago
Very clean and easy to find. We felt right at home!
Top guest favourite
Home in Las Cruces
4.99 out of 5 average rating, 87 reviews

Southwestern dream vacation-amazing views!

EmilieRating, 5 stars1 week ago
My four sisters and I stayed here for nearly a week. The house met our needs perfectly for hanging out inside in the spacious living room and dining room and outside on the two patios where we had lovely views of the mountains. The house was perfectly situated for hiking in the Organ Mountains. Loved this place and would come back.
Superhost
Guesthouse in Las Cruces
4.81 out of 5 average rating, 16 reviews

Sunrise Casita

PhyusinRating, 5 stars2 weeks ago
The stay’s view is amazing, perfect sunset, sunrise and stargazing. A clean and comfortable place to live in. As well as it was close to many good food places and around 45min away from White sand national park!
Guest favourite
Home in Las Cruces
4.87 out of 5 average rating, 31 reviews

Golf club Panoramic View, king bed

YvonneRating, 5 stars3 days ago
The location for what we need it is wonderful and convenient! No problems and the little hiccup we had was on the cooling system but I'm sure that will be fixed by the time we go back. Over all super excited to stay once again!
Guest favourite
Home in Las Cruces
4.88 out of 5 average rating, 32 reviews

Gary’s Full House

GenevieveRating, 5 stars2 weeks ago
Gary’s listing was perfect for our needs. This was our second stay at Gary’s house. It’s comfortable making you feel right at home.
Top guest favourite
Home in Las Cruces
5 out of 5 average rating, 95 reviews

Comfortable, relaxing home.

RubenRating, 5 stars1 month ago
This house was nothing short of amazing! Super clean and just as described. Abe was quick to respond and was super helpful with any questions I had. Will definitely stay here any chance I get when we are in Las Cruces! Hands down one of the top places I have stayed at.
Guest favourite
Home in Las Cruces
4.91 out of 5 average rating, 76 reviews

Pecan Palace w/ Game Room & HOT TUB (Near NMSU)

RosaRating, 5 stars3 days ago
Francisco, our host, was very responsive and accommodating. The home itself was clean and free of clutter. I really enjoy walking into a Airbnb that isn't overwhelmed with nicknacks and feels peaceful. My girls really didn't use many dishes but it looked like the kitchen was well equipped with what one would need if they are preparing meals there. Beds and linens were clean and comfortable and the large dining room table is perfect for 8 with 2 more bar chairs next to countertop. Open living and kitchen floor plan. The neighborhood is quiet and has new or newer homes and slightly tucked out of the way but super close to NMSU area. Probably 5 minute drive to NMSU. I would recommend this home from large groups to just a few, as there were plenty of beds and bedrooms. The garage is turned into a super cute game room with it's own mini-split ac that kept it cool. You'll have to park in driveway but no worries-great neighborhood.

Quick stats about vacation rentals in Mesilla

  • Total rentals

    80 properties

  • Nightly prices starting at

    $55 CAD before taxes and fees

  • Total number of reviews

    8K reviews

  • Family-friendly rentals

    40 properties are a good fit for families

  • Pet-friendly rentals

    40 properties allow pets

  • Rentals with a pool

    20 properties have a pool

Destinations to explore

  1. Airbnb
  2. United States
  3. New Mexico
  4. Doña Ana County
  5. Mesilla