Boutique hotel vacation rentals in Midtown East, Manhattan

Find and book unique boutique hotels on Airbnb

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Popular amenities for Midtown East, Manhattan boutique hotels

Family-friendly boutique hotels

Hotel room in Greenpoint
4.86 out of 5 average rating, 68 reviews

Superior @ Box House

TimRating, 5 stars9 months ago
Stayed for on site wedding. Room was nice and clean and staff was helpful and friendly. Highly recommend.
Hotel room in Greenpoint
4.89 out of 5 average rating, 35 reviews

Superior @ Box House

LauranRating, 5 stars8 months ago
Great stay, we were there for a wedding and the food we had was great too!
Hotel room in Midtown Manhattan
4.65 out of 5 average rating, 513 reviews

Freehand New York - Private Bunk Room

ThomasRating, 5 stars2 months ago
Perfect spot for 4 friends on a weekend trip to NYC
Hotel room in Midtown Manhattan
4.48 out of 5 average rating, 1,052 reviews

Freehand New York - Premium Queen Room

ParisageRating, 5 stars2 weeks ago
This was the perfect location for us, everything was 2-4 subway stops away and the area itself is awesome! We had the most incredible trip, having multiple restaurants downstairs that were delicious was so convenient. The staff is so friendly and helpful, especially Hero!!! The hotel itself was so cute and artistic, wouldn’t change a thing!
Superhost
Hotel room in Great Neck
4.76 out of 5 average rating, 130 reviews

Boutique Hotel in the heart of the North Shore

JenniferRating, 5 stars1 week ago
The room was giant, the bed was comfy and everyone was very helpful!
Guest favourite
Hotel room in Harlem
4.83 out of 5 average rating, 106 reviews

The Chester Himes Room at The Harlem Flophouse

RuthRating, 5 stars1 month ago
I almost wish i hadn't seen the photos - the Flophouse is unique, quirky and beautiful. René was very thorough and responsive and his friend who looked after the place in his absence was lovely. This was a wonderful place to come home to because it felt like home, not a sterile hotel room. Thank you René and Felipe
Hotel room in Greenpoint
4.76 out of 5 average rating, 33 reviews

Superior @ Box House

YemenRating, 5 stars16 months ago
The place is in a quiet neighborhood and close to the river, we always returned around midnight and felt calm walking back. The rooms are clean and just like the photos. The metro station is a 10-minute walk away. A new jacket we had bought disappeared and no one took responsibility. If there is an event or party in the hotel, a lot of noise can be heard in the rooms. In general, it was a good place to stay and we had a window with an incredible view of the city.

Quick stats about boutique hotel rentals in Midtown East, Manhattan

  • Total rentals

    160 properties

  • Total number of reviews

    4K reviews

  • Pet-friendly rentals

    40 properties allow pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    90 properties include access to wifi

  • Popular amenities

    Kitchen, Wifi, and Pool

Destinations to explore

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  2. United States
  3. New York
  4. New York
  5. Manhattan
  6. Midtown East
  7. Boutique hotel rentals