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Vacation rentals in Onondaga County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Onondaga County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A living room is displayed with a dark leather sofa and a light-colored sectional couch, arranged around a central coffee table. Soft lighting is provided by ceiling fixtures. A piece of wall art adds color, while a closed door and a window with light curtains are visible.
Guest suite in Syracuse
4.8 out of 5 average rating, 201 reviews

Private Apartment in the heart of Syracuse

Spacious basement apartment large enough for 3 people, includes a bedroom, living room, a large walk-in closet, smaller secondary closet, a kitchen and a 75 inch 4K TV. Located in the Sedgwick area,10 minutes away from Syracuse airport, 7 minutes away from Syracuse University, and downtown Syracuse. The house is located in a quiet and safe area. walk and pet-friendly neighborhood. The apartment is air-conditioned, extremely fast WiFi is also available for your use, looking forward to seeing you!

Guest favourite
A spacious suite features a comfortable seating area with a neutral-toned sofa and a small side table. A queen bed is dressed in warm tones, with a large mirror and dresser positioned nearby. Natural light flows in through sliding glass doors that lead to a balcony.
Loft in Syracuse
4.97 out of 5 average rating, 117 reviews

Downtown Suite with Balcony

This brand new suite is truly in the middle of everything; situated between the Landmark and the War Memorial, a block from the Onondaga Courts, the Hotel Syracuse, across from the Galleries and TCG Player, a block from the Equitable Towers and 2 blocks from the Salt City Market and Syracuse.com. Other notable destinations include two blocks from the MOST and Armory Square and one mile to Syracuse University. The apartment has granite counters, tiled bathroom, washer & dryer and an office area.

Superhost
A living area features a vintage burgundy sofa complemented by an ornate wooden coffee table. Tall windows allow natural light to illuminate the space, while potted plants adorn the surroundings. Unique wall art adds character to the room, enhancing the Victorian theme.
Guest suite in Syracuse
4.87 out of 5 average rating, 91 reviews

Victorian Antique 1 Bdrm Ground Fl Apartment

1 Bedroom available 7min from downtown Syracuse. 3min from Destiny Mall, and train/bus stations. This unit has an victorian style theme to it that showcases local art within the local area About 10 minutes from most areas of syracuse in every direction due to the central location and easy access to highways Keep in mind this is an inner city location it's safe but more of a working class neighborhood. There are security cameras around the property and off street parking in the back as well.

Guest favourite
A spacious living area is illuminated by natural light through large windows with black frames. A grey sectional sofa is adorned with an assortment of decorative pillows. A glass coffee table is positioned in front of the sofa, enhancing the open atmosphere of the room.
Apartment in Syracuse
5 out of 5 average rating, 13 reviews

City Chic Best of Armory Sq!

At the City's center, Bentley Lofts rise to the sky. Beyond it's ornate brick facade period details await you through its handsome doors. A lobby with 15 foot ceiling greets you. Artworks curated from local artists abound mixing old and new seamlessly. In the loft itself, the finishes are the stand outs in the custom kitchen, spa bath and a living space which is bathed in natural light. A Queen sized wall bed with luxurious linens hosts a desk that hideaway with ease . Exhale, relax, enjoy!

Guest favourite
A spacious bedroom features a neatly made bed with a textured cream duvet and a decorative rust-colored throw blanket draped over the side. Wooden wall art adds depth above the headboard, while natural light filters through a partially open window, framed by light curtains.
Home in Syracuse
4.98 out of 5 average rating, 131 reviews

Estudio solo para dos.

Un apartamento tipo estudio de concepto abierto, lo que significa que no tiene divisiones interiores ni puertas que separen las distintas áreas. El espacio es continuo, integrando la zona de dormitorio, sala y cocina en un mismo ambiente amplio y funcional. El baño mantiene cierta privacidad en las áreas de la ducha y el inodoro, gracias a su diseño y distribución, pero no cuenta con una puerta de acceso, manteniendo la estética abierta y moderna del conjunto. espacioso para dos huéspedes.

Guest favourite
The modern kitchen boasts a handcrafted wood ceiling and adjacent center island, paired with sleek, stainless steel appliances. Two bar stools are positioned at the island for casual seating. Natural light filters through the window, highlighting the warm wood tones and contemporary finishes.
Home in Syracuse
4.95 out of 5 average rating, 62 reviews

Elegant 2BR w/ Custom Wood Charm

Welcome to our all-new, freshly renovated 2-bedroom retreat in Syracuse’s West Side! Conveniently located near everything Syracuse has to offer—Destiny USA, Downtown, Syracuse University, Tipp Hill, the NY State Fair, restaurants, and nightlife. This peaceful upstairs unit features brand-new steel appliances, spacious bedrooms, and a cozy living room. The handcrafted wood kitchen boasts a stunning wood ceiling and a center island. Enjoy a serene, private stay with all the comforts of home!

Top guest favourite
A single-story house is situated on a lush green lawn, framed by a large blossoming tree. A driveway leads to a garage with a single door, while large windows provide natural light to the interior. Soft blue skies and greenery complete the exterior view.
Home in Syracuse
4.98 out of 5 average rating, 309 reviews

Charlie's Place

Our place is located in a quiet and safe neighborhood just off the interstate - 10 minutes from Syracuse University, LeMoyne College, hospitals and downtown. It is just minutes away from Starbucks, Panera's, Wegmans and numerous other restaurants and shopping facilities. It is also very close to the Erie Canal trail for walking, jogging or biking. We have chosen to go with an Adirondack theme with our decor. We live just across the street and you will enjoy total privacy when you stay.

Superhost
A modern living area features a deep blue sofa adorned with decorative pillows. A glass coffee table stands in front of it. Three round mirrors reflect light from the stylish ceiling fixture. French doors open to a balcony, enhancing the airy feel of the space.
Apartment in Syracuse
4.91 out of 5 average rating, 33 reviews

Charming renovated apt near hospitals/Rt81/Upstate

This recently renovated downtown apartment is a charming & delightful space located in the Little Italy area. This 2nd-floor walk-up (no elevator) is above a high-end Italian bakery in a historic building adjacent to St Joseph's Hospital & Rt 81. Completely remodeled this bright & airy space has high ceilings, french doors with Juliet balcony & big windows. Centrally located in the city 5 minutes from SUNY Upstate, SU, Armory Sq & Destiny. In-unit laundry. Free parking in private lot.

Guest favourite
The modern kitchen features wooden cabinets and granite countertops. Stainless steel appliances, including a refrigerator, oven, and dishwasher, are present. Ample lighting is provided by recessed fixtures. The floor is finished with light-colored wood, creating a bright workspace that is practical and inviting.
Guesthouse in Syracuse
4.93 out of 5 average rating, 164 reviews

Carriage house studio/book nook

SYR second floor studio and first floor book nook in detached carriage house next to owner occupied home. Private. Modern. Authentic. Near SU, downtown, and hospitals. House backs up to beautiful Elmwood park and our family garden. Perfect for 1 or 2 (potentially 3). Great for coffee, book, and nature lovers. Stairwell to apartment is narrow and could be a challenge for some. Access to fenced private family garden if you like. We are often around and outside but the apt is very private.

Guest favourite
A spacious living area features a comfortable gray sofa with decorative pillows, a stylish area rug, and a mounted television. Natural light enters through windows, while an open doorway leads to a bedroom with a bed framed by modern artwork. A dining table is set in the background.
Apartment in Syracuse
5 out of 5 average rating, 12 reviews

Entire Modern Cozy 2BR Apt mins SU, LeMoyne, DT

Retro-inspired retreat with bold design, workspace, and natural light. Perfect for remote work or weekend stays—just minutes from Syracuse University, Le Moyne, and Downtown attractions. 🎓 Universities & Colleges Syracuse University – ~2.5 miles / ~7 minutes Le Moyne College – ~1.5 miles / ~5 minutes SUNY Upstate Medical University – ~3 miles / ~8 minutes 🏟️ JMA Wireless Dome (Carrier Dome) – ~2.5 miles / ~7 minutes

Guest favourite
A modern workspace is presented with a minimalist desk, a comfortable grey chair, and a decorative plant. A marble top coffee table and a gray patterned throw blanket on the sofa add style. Artwork by Matisse is displayed on the wall.
Apartment in Syracuse
4.92 out of 5 average rating, 76 reviews

Newly renovated & modern 2-bedroom apartment

Enjoy a stylish stay at this newly renovated apartment. Minutes from downtown, Syracuse University, Destiny USA, and top hospitals. This thoughtfully designed space features two bedrooms with comfy queen beds, a dedicated workspace, and a fully equipped kitchen. Perfect for business travelers, University visits, or a weekend getaway. Just 12 minutes from the airport, with easy access to dining, shopping and entertainment.

Guest favourite
A cozy living and workspace area is presented with modern furnishings. A large sectional couch is positioned beside a sleek desk equipped with a computer and office supplies. Natural light fills the room through a window, highlighting wooden floors and framed artwork on the walls.
Home in Syracuse
4.95 out of 5 average rating, 312 reviews

★ Quiet Gem minutes to SU, Downtown & Westcott! ★

Centrally located and cozy gem in the quiet, safe, and friendly Meadowbrook neighborhood. Minutes away from the center of Syracuse University, the Carrier Dome, Le Moyne College, and shopping centers. Just 4 minutes to the Westcott Theater by car and a pocket of unique restaurants. My home features everything you need for a comfortable stay in Syracuse. I'd love to have you come to enjoy the beautiful area!

Popular amenities for Onondaga County vacation rentals