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Vacation rentals with lake access in Pickens County

Find and book unique lake-access rentals on Airbnb

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Popular amenities for Pickens County lake-access rentals

Lake-access house rentals

Guest favourite
Home in Six Mile
4.93 out of 5 average rating, 40 reviews

Lakefront 5bed with outdoor areas, dock and kayaks

NanceRating, 5 stars6 months ago
We were in town for a family wedding and everyone enjoyed it. So much so that many said this would be great for holiday gatherings. Thank you so much for making it a great stay for my family!
Superhost
Home in Seneca
4.83 out of 5 average rating, 30 reviews

Lakefront Escape

ThomasRating, 5 stars1 month ago
Stayed while visiting our daughter at Clemson. We thought the location was great, close enough to school, shopping, food, but nice and quiet in the off season with a beautiful park-like neighborhood. The house worked great for us and had everything we needed for a comfortable week long stay. Thanks for sharing your place.
Guest favourite
Home in Seneca
4.91 out of 5 average rating, 35 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

MilaRating, 5 stars2 weeks ago
Visited Clemson with my family so that my son could see the campus before starting this fall. The location is situated beautifully on a serene lake. The house is exactly as pictured, with striking decor. The kitchen was well equipped with everything I needed. We appreciated being greeted so warmly with snacks, and Easter cupcakes. We loved the kayaks, a beautiful way to spend a warm spring day. Thank you Lauren!
Top guest favourite
Home in Six Mile
4.97 out of 5 average rating, 86 reviews

Lake Keowee waterfront private cove Close 2Clemson

BettyRating, 5 stars4 weeks ago
The house was amazing. Large enough for my whole family 7 adults and 6 kids. Layout of house was great , everyone had their own little areas. Lots of places to gather outside ( we are outdoor people). Beautiful views and very peaceful. Daniel’s response time was amazing. Very friendly and helpful.
Guest favourite
Home in Seneca
4.94 out of 5 average rating, 17 reviews

Lake House Retreat Near Clemson

LindseyRating, 5 stars1 week ago
We had the best time at Kelly’s place for our family friends’ getaway! 4 adults and 4 little ones (including two toddlers and a baby) stayed comfortably. The master bedrooms were great for pack 'n plays-one fit perfectly in the upstairs closet, and the basement master had a cozy spot near the washer/dryer, great for naps. The kids loved the playroom with toys, a play rug, and bunk beds. The living room was huge and uncluttered, great for all hanging out and letting the little ones play safely. We loved the beautiful back deck with outdoor seating and water views. Being right on the water with a private dock was a huge plus, and renting a boat from Clemson Marina (just 12 minutes away) made for an awesome lake day. The big, gated backyard gave the kids lots of space to run around safely. Everything was super clean, and Kelly was a wonderful host. Plus, it’s very close to Clemson! We’re already planning to come back for a longer stay. Thank you, Kelly, for a fantastic experience!
Superhost
Home in Sunset
4.9 out of 5 average rating, 49 reviews

Lake Keowee Hideaway Lake Access in a Private Cove

DanaRating, 5 stars3 months ago
We very much enjoyed our stay at Robert’s place in Sunset SC. It suited our 3 generations of family that we had there. The kitchen table was great with room for all 8 of us plus more! The bedroom situation was wonderful with I/2 baths stuck strategically around the house. Lots of games and puzzles for the kids. Here were a few items to mention for future visitors: there are 3 stories in this house so be prepared to hike, and discuss the heating/cooling situation with other guests before going to bed as the middle floor thermostat is in one of the bedrooms.
Superhost
Home in Seneca
4.85 out of 5 average rating, 217 reviews

Cozy Lake House 5 miles from Clemson w Dock

JustinRating, 5 stars2 weeks ago
Great place to stay! Very clean and they have everything you need. We really enjoyed and will be back! Highly recommended
Guest favourite
Home in Salem
5 out of 5 average rating, 9 reviews

New! Heart of Palmetto on Lake Keowee w/ Boat Dock

WalkerRating, 5 stars8 months ago
The house was great for what we paid. It seems small from the outside, but very well played out and spacious on the inside. We had two family’s(6-kids & 4 adults) and it was plenty of room and separation if needed between kids and adults. Would recommend for the price, we were extremely happy with our stay.

Lake-access apartment rentals

Apartment in Seneca
4.75 out of 5 average rating, 4 reviews

Lakeside Clemson apartment

CeilRating, 5 stars3 weeks ago
Wonderful stay. It was very quiet. The location was perfect. Condo was clean and comfortable. I asked for a last minute change and Dorian was very gracious with accommodating me. I will stay there again!
Superhost
Apartment in Sunset
4.74 out of 5 average rating, 19 reviews

"Greenbrier" Home in the Joccassee Wilderness

AprilRating, 5 stars2 weeks ago
My family and I absolutely enjoyed our little getaway here. The first night we woke up to it being over 85 degrees in the home but Tami was quick to respond and immediately had two window A/C units placed in the home to keep it cool. We are already talking about our next adventure and staying at this location again! Thank you Tami for allowing my family to celebrate the Easter holiday here!
Top guest favourite
Apartment in Six Mile
5 out of 5 average rating, 19 reviews

Condo at Lake Keowee

RittaRating, 5 starstoday
Craig and Robin’s condo is the perfect home away from home at Lake Keowee and they are great hosts. The condo was very comfortable, clean, spacious and well appointed. We really enjoyed sitting on the rockers on the patio and watching the sunset. It’s convenient to SWU and Clemson but quiet and relaxing. We highly recommend!
Apartment in Clemson
4.86 out of 5 average rating, 7 reviews

Comfortable Stay with Pool + 5 Min to CU

MatthewRating, 5 stars1 month ago
Everything was a staged an convenient!
Top guest favourite
Apartment in Seneca
5 out of 5 average rating, 23 reviews

3BR Ground floor condo - 2.4 Miles to Death Valley

LanceRating, 5 stars4 weeks ago
We had an amazing stay for the Clemson Spring Game! The space is absolutely beautiful, the pictures don’t do it justice. The hosts were fabulous and constantly kept us in communication with what we needed and even went out of their way to take care of us when we had a small issue. Couldn’t recommend more! We will definitely be back. It was too far to walk to the stadium, but we were able to get over there in less than 5 minutes in the car.

Lake-access cottage rentals

Guest favourite
Cottage in Salem
4.75 out of 5 average rating, 28 reviews

Lake Front Cottage/Floating Dock

HuntRating, 5 stars6 months ago
Wonderful stay. The house and space was so cozy and we wish we could have spent more time there. Really loved the rustic drive to the house. Felt so isolated from everything! Would definitely go back and would recommend it to anyone.
Guest favourite
Cottage in Sunset
4.95 out of 5 average rating, 113 reviews

River Cottage Nature Privacy

NanceeRating, 5 stars5 months ago
We had a wonderful stay and our kids had a great time too! It was so peaceful being right on the river. The host was very helpful and always quick to respond. We will definitely be back!
Guest favourite
Cottage in Easley
4.93 out of 5 average rating, 68 reviews

Cozy Cottage on the lake

DonnaRating, 5 stars10 months ago
We had a wonderful stay at the cottage. We loved the pool and the grankids loved it too. The cottage was clean , comfy, and cozy. The cottage was very peaceful and private, located on a dead end road. We highly recommend a stay . Will book again.
Cottage in Salem
4.82 out of 5 average rating, 60 reviews

Jocassee Landing Lake Cottage - 1 mi to Boat Ramp!

BenjaminRating, 5 stars2 weeks ago
I had a wonderful stay at this charming and tranquil cottage. The house was impeccably clean, beautifully decorated, and situated in a peaceful setting that provided the perfect escape from the hustle and bustle, but was still close to the boat ramps for lake Jocassee which was great. The quiet surroundings made for restful nights and serene mornings.​ Marshall was an exceptional host, he was friendly, polite, and incredibly helpful throughout my stay. The instructions he sent for little things around the house made everything that much easier. He ensured that everything was in order and was always available to answer any questions I had. His attention to detail and commitment to guest comfort truly enhanced my experience.​ I highly recommend this property to anyone seeking a relaxing getaway with top-notch hospitality. I look forward to returning in the future!​
Top guest favourite
Cottage in Six Mile
4.99 out of 5 average rating, 195 reviews

Lake Keowee Waterfront Cottage - Private Retreat

GuyRating, 5 stars8 months ago
One of a kind experience, the place itself coupled with the hosts' hospitality and responsiveness. There are truly limited superlatives one can use to capture the unique beauty and intimacy the property provides.
Top guest favourite
Cottage in Pickens
4.98 out of 5 average rating, 58 reviews

At Table Rock+Private Trail+King Bed+Fire Pit+BBQ

LauraRating, 5 stars1 week ago
BT's cottage was a perfect place to stay while we explored Table Rock during the birding festival. Super convenient to the park and beautiful views! Tons of birds! Will definitely return!

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