Vacation rentals in La Mesa

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Top-rated vacation rentals in La Mesa

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Guest favourite

Guesthouse in La Mesa

4.92 out of 5 average rating, 208 reviews

Fig Tree Bungalow

Enjoy your stay in San Diego in this newly renovated guesthouse. Centrally located about a mile from Hwy 8, Hwy 125, and the Grossmont Trolley Station & Transit Center. Only a 15-20 minute drive to downtown, the airport, the beaches, and most of San Diego's other popular tourist attractions. This cozy, two-story, detached unit is located behind my home, and has its own private entrance and partitioned yard for your enjoyment. There's plenty of street parking directly in front of the house.

Aug. 14 – 21

$196 CAD per night

Guest favourite

Home in La Mesa

4.85 out of 5 average rating, 177 reviews

Newer "Manor Studio"

Centrally located in San Diego County this brand new studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

Oct. 24 – 31

$167 CAD per night

Guest favourite

Guesthouse in La Mesa

4.97 out of 5 average rating, 169 reviews

Cozy Coop with a View

This house is perfect for a private get away. There is a patio bar & a large picture frame window that commands the best views in the area. Sit & enjoy the large patio right off the entryway to the house. I have been told our home used to be a chicken coop in the 50-60's. It is far different now, we just finished a complete remodel. Everything is updated, upgraded & ready for you. Being on the top of the hill you get the nice views, but sounds carries as well, please respect the neighbors.

Oct. 14 – 21

$214 CAD per night

Guest favourite

Home in La Mesa

4.93 out of 5 average rating, 179 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Aug. 31 – Sep. 7

$234 CAD per night

Guest favourite

Barn in La Mesa

4.95 out of 5 average rating, 317 reviews

Enchanting Barn San Diego/La Mesa

DESCRIPTION: Relax and Enjoy the converted barn that is safe, cozy, and private. The unit has it's own private entrance secured with a Keyless entry lock. Inside is a Cal King therapy foam bed, TV, Blu-ray player, Bluetooth/CD stereo, and additional USB connection. Extra space has a large desk area. The unit has a private bathroom that includes a walk in shower. Freshly washed towels & linens are provided. *we have a pet goat that would love to meet you! Dedicated 5g Internet access

Oct. 4 – 11

$155 CAD per night

Guest favourite

Apartment in La Mesa

4.98 out of 5 average rating, 122 reviews

Lovely Hideaway Studio by Village-Private Patio

Enjoy the cool vibe at this unique rustic getaway tucked back on a tree-lined hill 5 minutes above City of La Mesa Village, 20 minutes from downtown San Diego. The studio is on the ground floor of our two-story house. We live on the 2nd floor, and the studio is it's own completely private space. 5 miles to San Diego State University; 16-20 miles to San Diego beaches; 10 miles to Downtown San Diego; 15 miles to Sea World San Diego; and 13 miles to the World Famous San Diego Zoo!

Mar. 10 – 17

$150 CAD per night

Guest favourite

Bungalow in La Mesa

4.93 out of 5 average rating, 192 reviews

Two bedroom garden bungalow in West La Mesa

Hi there! My name is Janice and I bought this charming little 1943 bungalow in west La Mesa a few years ago to use as a primary residences that has now transitioned to a short term rental. This location is close to public transit (bus and trolley), 10 miles from the San Diego Zoo, 15 miles from the beach, and 10 miles from Little Italy, and the Convention Center. The accessible space for guests includes 2 bedrooms, a bath, a living room, kitchen, dishwasher, washer & dryer.

Dec. 10 – 17

$233 CAD per night

Guest favourite

Guesthouse in El Cajon

4.98 out of 5 average rating, 191 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Sep. 24 – Oct. 1

$177 CAD per night

Guest favourite

Guest suite in La Mesa

4.96 out of 5 average rating, 103 reviews

La Mesa Garden Suite

Welcome to our newly remodeled La Mesa Garden Suite - the perfect destination for your San Diego vacation! Nestled beneath a main residence in a lush backyard, this tranquil downstairs unit offers the perfect blend of privacy and convenience. With its own private entrance, patio, and full bathroom, you'll enjoy a delightful retreat while still benefiting from the warm hospitality of our home. If you need anything during your stay don't hesitate to ask!

Aug. 4 – 11

$207 CAD per night

Guest favourite

Guesthouse in La Mesa

4.99 out of 5 average rating, 133 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego and 18 minutes to a beach. Unique private property with mid-century and one-of-a kind furniture in a comfortable living space. Enjoy IPAs on your private deck or coffee in bright Fiesta cups, watch TV while leaning back in the handcrafted Nicaraguan rocker or the 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed. Like eclectic? This place exudes it.

Aug. 27 – Sep. 3

$235 CAD per night

Guest favourite

Cottage in La Mesa

4.97 out of 5 average rating, 278 reviews

La Mesa House On a Hill With Mountain Views!

SUNRISE PERCH - A standalone guest house, perfect spot for your San Diego stay! Enjoy inspiring sunrise views from the deck or relax indoors with super fast WiFi and a 43" TV. Enjoy a full kitchen! The king bed is super comfy and the bathroom is stocked. The space is only for those looking for quiet. No partying/loud socializing. Families welcome! Located 20 min from downtown San Diego and 25 min from the nearest beach (Ocean Beach).

Sep. 1 – 8

$251 CAD per night

Guest favourite

Apartment in La Mesa

4.97 out of 5 average rating, 141 reviews

Mt. Helix apartment with panoramic views

Mt. Helix apartment with great views from private balcony located centrally in La Mesa on quiet street. Apartment is on 2nd floor of private home on an acre lot. PLEASE NOTE: Apartment is on 2nd floor and an outside staircase is required to enter the apartment. 1 parking space is designated in driveway. Quiet Hours are 10:00pm - 7:00am. No smoking/vaping anywhere on the property.

Aug. 17 – 24

$153 CAD per night