
Hotel vacation rentals in San Luis Obispo County
Find and book unique hotels on Airbnb
Top-rated hotels in San Luis Obispo County
Guests agree: these hotels are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for San Luis Obispo County hotels
Family-friendly hotels

Upscale Modern ADA Two Queen Room - Wharf/Downtown

The Louise Room in Cambria's Squibb House B&B

The Garden Suite - Marina Street Inn

Deluxe & Upscale Two Queen Suite - Wharf/Downtown!

Historic 1917 Lavender Inn - Sage Room

The Bordeaux Suite - Marina Street Inn

Upscale Modern ADA One Queen Room - Wharf/Downtown

The Gothic Room in Cambria's Squibb House B&B
Hotels with a pool

Rare Find! Full Kitchen, Free Parking, Onsite Pool

Free Parking, Free Breakfast, Beach Nearby

San Luis Bay Inn - 1 Bedroom Suite

MS6 California|2 Full Beds|NS

Find out why SLO is the ‘happiest city in America’

Cozy Room w/ Queen-sized bed, Private Bath + More

Motel 6 San Luis Obispo, Ca - South 1 Qu

Motel 6 San Luis Obispo, Ca - South 1 Ki
Hotels with a patio

Family Suite

Waterfront Suite Two Queen Beds Full Ocean View

Lux Corner Suite Ocean Views (317)

1B WorldMark Resort beach access

Family Retreat Suite by 456 Inn

Lux King Retreat Suite

Pismo Beach Resort, weeklong 7/29-8/5, 2025

Standard Two Queen Bed Room
Destinations to explore
- Rentals with an EV charger San Luis Obispo County
- Family-friendly rentals San Luis Obispo County
- Tiny house rentals San Luis Obispo County
- Rentals with breakfast San Luis Obispo County
- Beachfront rentals San Luis Obispo County
- Rentals with a kayak San Luis Obispo County
- RV rentals San Luis Obispo County
- Rentals with outdoor seating San Luis Obispo County
- Townhouse rentals San Luis Obispo County
- Condo rentals San Luis Obispo County
- Rentals with lake access San Luis Obispo County
- Bed and breakfasts San Luis Obispo County
- Rentals with a washer and dryer San Luis Obispo County
- Cabin rentals San Luis Obispo County
- Waterfront rentals San Luis Obispo County
- Farmstay rentals San Luis Obispo County
- Rentals with pools San Luis Obispo County
- Apartment rentals San Luis Obispo County
- Guesthouse rentals San Luis Obispo County
- Cottage rentals San Luis Obispo County
- Villa rentals San Luis Obispo County
- Rentals with beach access San Luis Obispo County
- Rentals with a firepit San Luis Obispo County
- Rentals with a hot tub San Luis Obispo County
- Rentals with a fireplace San Luis Obispo County
- Pet-friendly rentals San Luis Obispo County
- House rentals San Luis Obispo County
- Private suite rentals San Luis Obispo County
- Rentals with a patio San Luis Obispo County
- Hotel rentals California
- Hotel rentals United States
- Cayucos Beach
- Moonstone Beach
- Montaña de Oro State Park
- Cayucos State Beach
- Natalie's Cove
- Hearst San Simeon State Park
- Morro Strand State Beach
- Dairy Creek Golf Course
- B & E Vineyard & Winery
- Mission San Luis Obispo de Tolosa
- Pismo State Beach
- Morro Rock Beach
- Seal Beach
- Bianchi Winery
- Olde Port Beach
- Pirates Cove Beach
- Morro Bay Golf Course
- Sand Dollars
- Point Sal State Beach
- Bovino Vineyards
- Baywood Park Beach
- Allegretto Wines
- Morro Strand State Beach Day Use Area
- Sandspit Beach
- Things to do San Luis Obispo County
- Nature and outdoors San Luis Obispo County
- Food and drink San Luis Obispo County
- Things to do California
- Food and drink California
- Nature and outdoors California
- Sports activities California
- Wellness California
- Tours California
- Entertainment California
- Art and culture California
- Sightseeing California
- Things to do United States
- Tours United States
- Nature and outdoors United States
- Sightseeing United States
- Art and culture United States
- Food and drink United States
- Wellness United States
- Entertainment United States
- Sports activities United States