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Vacation rentals in Santa Cruz County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
A modern kitchen is equipped with stainless steel appliances, including a refrigerator and dishwasher. White cabinets provide ample storage, while a dining table for four sits beside a window, allowing natural light to pour in and offering views of the surrounding landscape.
Home in Elgin
4.96 out of 5 average rating, 114 reviews

Modern Elgin Home: Walk to Wineries + Pets Welcome

With its elegant design, secluded location, and 1-bedroom, 1-bath, ‘Starry Night Guest Retreat’ is the perfect cozy vacation rental! Start your days off by relaxing on the patio and admiring the views of the Mustang Mountains. When it’s time to explore, head to Deep Sky Winery for a glass of wine, try out some nearby birdwatching, or enjoy the farm animals grazing the meadow. Finish your stay with a visit to the old town of Tombstone and Kartchner Caverns State Park to see all that Elgin offers!

Top guest favourite
The large private deck overlooks expansive high desert mountain views. A grill sits ready for use, accompanied by a small potted plant on a metal cart. Lush greenery frames the view, providing a serene outdoor space.
Apartment in Sonoita
5 out of 5 average rating, 148 reviews

High Desert Wine Country

Take it easy at this tranquil getaway. Breathtaking views, 5000 feet altitude. See wineries or take a day's outing and visit local attractions. Second story apartment is a newly renovated space over hosts' garage (guests must be capable of climbing one flight of spiral stairs). It has a full kitchen (Including dishwasher), full bath (shower only - no tub), nice sized bedroom with queen bed and closet. Second story large private deck. NO DIRT ROADS TO PROPERTY! Adults only and (sorry!) no pets.

Guest favourite
A hammock is gently draped between two trees, with the fabric partially visible in the foreground. The background features a stunning sunset, casting soft hues across the sky. The landscape is open, with sparse vegetation and rolling hills creating a tranquil environment.
Guest suite in Nogales
4.94 out of 5 average rating, 136 reviews

Patagonia Lake Hideaway

PRIVATE SPACE! $105 p nite NO CLEANING FEES but airbnb charges its own fees. king bed, picture window, sofa, french doors,electric fireplace, Private courtyard, patios, gardens,sunrise over Patagonias,sunset behind the Atascosas. Birding paradise.Also great for hunters, hikers.Lake minutes away with boat rentals, swimming, fishing, hiking, small beach. Easy travel toTombstone, AZ Trail, Tubac, Golf Course, Kartchner caverns, Patagonia, Mexico, wine and spirit tasting .check in/check out flexible

Top guest favourite
Guest suite in Patagonia
4.95 out of 5 average rating, 127 reviews

Box T Studio

The Studio is a moderate sized living quarters set up purposely for lounging, relaxing, personal entertainment and rest. Set within the compound of a historical property (The Box T Ranch built in 1902), the studio is the perfect home plate for all your Southern Arizona adventures. It includes an amazing king size bed, comfortable furnishings, a 57" Sony TV, mini fridge, microwave, Keurig, 2 person walk in shower and an AC unit. We are within 5 minute walking distance into town. Perfect getaway!

Top guest favourite
The bedroom features a king-size bed with a light blue quilt and two accent pillows. Soft yellow curtains frame the window, allowing natural light to fill the space. Two bedside lamps with red shades illuminate the room, and a framed artwork hangs above the headboard.
Guest suite in Tubac
4.96 out of 5 average rating, 146 reviews

Tubac Golf Resort Casita

The casita is located between the Golf Course and Tubac village. The casita has a private bedroom and bathroom with outside entrance. The private yard has a covered porch and outdoor kitchen. Inside is a king-size bed, table, chairs, refrigerator, microwave, coffee pot. Amenities include WIFI, local TV, Peacock. Weekly and long stay discounts. Early checkin/late checkout usually available... Please ignore the 13 photos at end. They are for my small house listing in case you are interested.

Guest favourite
A southwestern-style ranch home is nestled on expansive land, surrounded by rolling plains. The structure features a white exterior with traditional architectural elements. Majestic mountains are visible in the distance under a clear sky, enhancing the serene rural landscape.
Home in Elgin
4.94 out of 5 average rating, 158 reviews

Peaceful SW-style ranch home in wine country

Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).

Top guest favourite
A round mirror framed in metal reflects a cozy sleeping area featuring a colorful blanket on the spacious bed. The rustic brick wall is enhanced by a small natural wood piece placed below the mirror, adding a touch of texture to the interior.
Tiny homes in Elgin
4.97 out of 5 average rating, 122 reviews

Private casita on Thunder Mountain Ranch

It's the perfect "getaway" that's still "near" it all! Our stand alone southwestern fully equipped Casita offers comfortable accommodations in a very unique setting, surrounded by thousands of acres of the Coronado National forest. Located in the desirable Sonoita/Elgin area of Southern Arizona. From just soaking up the quiet serenity for a weekend, to an adventure filled longer stay, we can help tailor your experience to enjoy the many different things to see and do in the area.

Top guest favourite
A refreshing saltwater pool is framed by a spacious deck, lined with comfortable lounge chairs. The surrounding landscape features native plants and offers expansive views of the desert terrain and distant mountains under a dramatic sky.
Cottage in Patagonia
4.97 out of 5 average rating, 119 reviews

Kestrel Cottage at Birdsong Retreat

ATTENTION SUMMER BOOKINGS: Swamp cooler entire cottage and AC wall unit in queen bedroom. We provide fans. With monsoon rains, it’s too humid to use swamp cooler. Cottage priced to reflect the heat. Escape to serene high desert grasslands in Patagonia, AZ, offering 360-degree views at 4,058 feet offering respite from the Phoenix and Tucson heat. Nestled within BirdSong Retreat on 37 acres, the Kestrel Cottage promises luxurious accommodations and a focus on well-being.

Top guest favourite
An open studio cabin interior is highlighted by warm wood accents and a ceiling fan. A kitchenette with a full refrigerator and gas stove is visible. A spacious bed is located beside a seating area, with large windows offering views of the surrounding landscape.
Guesthouse in Elgin
4.97 out of 5 average rating, 100 reviews

Rustic Cabin with Mountain Views Close to Wineries

Escape to Southern Arizona's wine country with a trip to this Elgin studio cabin located on a horse ranch with unobstructed views of the Mustang Mountains. Relax on the deck sipping coffee or local wines. Visit any of the nearby 21 wineries like Deep Sky and Autumn Sage. Walk to the new Flying Kite winery. Venture out to Patagonia Lake or visit Parker Canyon Lake. Take a day trip to Bisbee or Tombstone. Enjoy the wide-open spaces. We are pet-friendly with no fee.

Top guest favourite
A single-story building constructed with natural stone and warm-toned stucco is set against a backdrop of grassy landscaping. A covered outdoor area is visible, along with a clear sky, creating a serene and peaceful setting.
Cottage in Patagonia
4.95 out of 5 average rating, 124 reviews

Country house with spectacular views

Disconnect from your worries in this spacious and serene private space, where you can enjoy natural light, contact with nature and beautiful natural views. It has a fully equipped kitchen, dining room, living room, living room with TV and reclining armchairs, 3 large bedrooms, a game room, laundry room and a beautiful porch where you can rest in the living room or in the outdoor dining room as well as enjoy beautiful sunsets. It also has a kiosk with lighting.

Guest favourite
The exterior of the apartment features a vibrant yellow adobe wall, accented by a decorative horse motif. A wooden bench sits beneath a window with wrought iron detailing, while potted plants add greenery to the entrance. Rain-soaked surfaces reflect the surrounding colors.
Apartment in Nogales
4.94 out of 5 average rating, 223 reviews

Las Hacienditas Large Two-Bedroom Apartment

Located in the beautiful town of Rio Rico. Just a few minutes from the Mexican border and from the art community at Tubac. A few blocks from a beautiful walking trail, gymnasium and several churches. This private apartment has all the amenities you need for a short or long stay. We take all the necessary steps to make sure the space is sanitary by disinfecting all areas and washing all bedding and linens to protect you and your family or guests.

Guest favourite
The guesthouse features a cozy sleeping area with a spacious bed dressed in simple linens. A comfortable sofa is positioned next to a wood bookshelf, which holds various decorative items. A desk and chair provide a dedicated workspace, with natural light filtering through the curtains.
Guesthouse in Rio Rico
4.87 out of 5 average rating, 368 reviews

Cozy Rio Rico guesthouse with a view

This spacious guesthouse is in an ideal rural setting. Located near the Mexican border, the art community at Tubac, and the old Spanish mission of Tumacacori, there is lots to see and do. (Not to mention many good golf courses.) I am looking forward to your visit! To make your stay both pleasant and sanitary I steam clean floors, sani-wash all linens and towels, and wipe counters, sinks and toilet with sanitizer spray. Rest easy here!

Popular amenities for Santa Cruz County vacation rentals