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Guesthouse vacation rentals in Santo Domingo Este

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Top-rated guesthouses in Santo Domingo Este

Guests agree: these guesthouses are highly rated for location, cleanliness, and more.

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Guest favourite
An outdoor area is visible, featuring gravel pathways and green grass. The building has multiple windows with black frames, allowing natural light to enter. Nearby, tropical plants and trees contribute to the serene environment, creating a peaceful atmosphere outside the studio.
Guesthouse in Ciudad Universitaria
4.89 out of 5 average rating, 62 reviews

Centric & Elegant Studio/Colonial Style/Ample Yard

Unique studio within a renovated property. Large patio with fence and electric gate. Ideally located, 2 miles away from the Colonial Zone, 3 from Downtown. Hospital, Laundry, Sea View within 2 blocks. Supermarket, restaurants, museums within 1 mile. Less than 0.5 miles away from 2 subway stations. Fast Wifi (100+ Mbps). Smart speaker can control lights, AC, adjust temperature or play your favorite music. 4K TV w/swivel base, includes YouTube, Netflix, PrimeVideo, Disney and Star+. Queen bed.

Guest favourite
A single-story studio is presented with a warm orange exterior and two front windows, framed by black metal bars. A gated fence and small grassy area enhance the inviting entrance, while a paved driveway provides access to the space.
Guesthouse in El Millón
4.95 out of 5 average rating, 37 reviews

Private Cozy Apartment Studio

One bedroom studio, centrally located in the heart of El Millón, Santo Domingo, where comfort, convenience, and warm space offers the intimate feel of a family home, featuring: A private entrance for your complete privacy. Dedicated parking for your convenience and peace of mind. Whether you're visiting for leisure or business, our studio is thoughtfully designed to meet your needs. Remote workers will appreciate the high-speed internet, ensuring uninterrupted connectivity throughout your stay.

Superhost
A cozy bedroom is highlighted by a white bed with a bright yellow pillow. A small vase holds cheerful orange flowers, adding a touch of color to the space. Rich wooden cabinetry can be seen in the background, contributing to the room's inviting atmosphere.
Guesthouse in Santo Domingo Este
4.79 out of 5 average rating, 34 reviews

Cozy 2 BR with BBQ

This 2 bedroom apartment with BBQ private area is truly bright and cozy . It takes 25 minutes to arrive from the airport. The spacious master bedroom has a queen size bed and the very bright single room have two twins bed. You have discount with our car rental services with airport pick-up. The neighborhood is very safe, is private with access control and very clean, there are many restaurants nearby many bars, gyms, movie theaters, shopping malls . The neighbours are lovely and quiet.

A spacious studio is equipped with a cozy bed and a small dining area featuring a round red table with two chairs. A bathroom door is visible, alongside a framed artwork hanging on the wall. Blue curtains provide a pop of color against the neutral walls.
Guesthouse in Santo Domingo Este
4.67 out of 5 average rating, 30 reviews

Santo Domingo studio apartment 40 minutes from the beach.

you will have the entire studio apartment just for you, enjoy the tranquility offered by the sector, an ideal place to rest and work, and a strategic point to travel to places of interest cleaning of the accommodation is at your expense during your stay, it is delivered clean, if you need you can request cleaning service for an additional charge. the yard is shared very rarely, usually only you will enjoy the yard, the hostess is in charge of cleaning the yard area.

Guesthouse in Santo Domingo Este
4.67 out of 5 average rating, 9 reviews

Grandparents' cottage

Enjoy a quiet, comfortable and private space, where you can rest, work and get to know Santo Domingo. This home is located 35 mins from Boca Chica beach and 15 mins from the National District. It's also less than 5 minutes away. Supermarkets, squares, clinics, fast food restaurants, recreation park, fuel station, shipping agencies and pharmacies. WE DO NOT RECEIVE DIFFERENT PEOPLE AT THE ACCOUNT OWNER

Top guest favourite
A bright living area features a decorative wall with a warm brick design, complemented by a wooden ceiling. A television is positioned on a simple black console, while a round dining table is adorned with a vase of elegant flowers, adding a touch of nature.
Guesthouse in El Millón
4.96 out of 5 average rating, 80 reviews

Cozy apartment for work / holidays.

Comfortable apartment, on second level, with private parking, ideal for holiday trips, congresses, jobs and others. Close to shopping centers, Recreational park, clinics, universities; 25 minutes from the colonial area. Located in downtown area of the city, in the urbanization El Millón del Distrito Nacional. Peaceful, residential place with access to the main roads of the city.

Guest favourite
A lush backyard features a swimming pool surrounded by greenery and decorative elements. A barbecue grill is positioned on a stone patio, while comfortable seating arrangements invite relaxation. Colorful plants and well-maintained flower beds enhance the serene outdoor setting.
Guesthouse in Residencial Alameda
4.86 out of 5 average rating, 63 reviews

Guesthouse

An oasis of tranquility in the middle of the city. This private area offers safety, comfort and exclusivity, ideal for those looking for a serene and safe environment. Surrounded by nature and with a design designed for wellness, it is the perfect refuge to disconnect from the urban hustle without departing from the convenience of the city. A true urban paradise.

Guest favourite
The exterior of the property features a modern one-story structure with a terracotta roof. Steps lead down to a clear pool, surrounded by well-manicured hedges and lush greenery. Soft lighting highlights the entrance, offering a welcoming presence during twilight.
Guesthouse in Santo Domingo
5 out of 5 average rating, 10 reviews

Guest House w/Pool near the American Embassy

You no longer need to leave the city to feel in the mountains, this is an independent 1 bed 1 bath Guest House in a closed residence with a 10-meter pool shared with the Hosts. With a Coway potable water filter. Supermarkets, Cinema, Shops, and Hair Salon nearby. A few minutes from the center of Santo Domingo and 1.8 km from the American Embassy.

Guest favourite
Guesthouse in Las Caobas
4.88 out of 5 average rating, 17 reviews

Your little corner of peace in SDO

Kick back and relax in this calm, stylish space. “Tu rinconcito de Paz” is an oasis in the middle of the city rush, take some fresh air in our outdoor Gazebo area, enjoy the privacy and security of our small but cozy house. Commercial centers as Carrefour and numerous restaurants are located at 8 minutes away from our spot.

Guest favourite
The outdoor area features a spacious parking lot with several vehicles, surrounded by greenery and landscaped pathways. A basketball court is visible in the background, alongside a multi-level patio area with seating for outdoor gatherings. Palm trees provide shade in this tranquil setting.
Guesthouse in Santo Domingo
4.92 out of 5 average rating, 12 reviews

U.S. Embassy Suites

Have fun with the whole family at this stylish place while taking it easy at a unique and tranquil getaway. Perfect while on the go or for appointments at the U.S. embassy. Guesthouse comes included with access to an olympic style pool, outdoor patio and barbecue grill. Great for evening get togethers and celebrations.

A wide view of a vibrant street lined with historic buildings features a prominent clock tower in the background. Arched doorways and balconies are visible, while pedestrians and birds inhabit the bustling area, showcasing a lively atmosphere.
Guesthouse in San Carlos
4.67 out of 5 average rating, 149 reviews

Cozy Separate Room in Santo Domingo Colonial

Estudio-anexo a la casa. Cómodo - espacioso, próximo a la zona colonial, palacio presidencial, parque independencia, Malecon. Primera ciudad del continente americano. Zona más turística de Santo Domingo. Most tourist area of ​​santo domingo! Great for sightseeing

An outdoor terrace is displayed with grey-tiled flooring, featuring a round table surrounded by four black chairs. Two potted plants are positioned on either side, and a large umbrella provides shade, while a distant cityscape is visible against a clear blue sky.
Guesthouse in Los Frailes
4.67 out of 5 average rating, 3 reviews

Mamuchi House 1 inhab. A/C, Zona Franca San Isidro

Apartamento de 1 habitación con a/c, baño privado, 3er. Piso. Ideal para ti que buscas un espacio cómodo cerca de la Zona Franca de San Isidro y Base aérea, descansas en un ambiente familiar. Tarifa base válida para 2 personas, una habitación.

Popular amenities for Santo Domingo Este guesthouses

Quick stats about guesthouse rentals in Santo Domingo Este

  • Total rentals

    60 properties

  • Nightly prices starting at

    $14 CAD before taxes and fees

  • Total number of reviews

    610 reviews

  • Pet-friendly rentals

    10 properties allow pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    60 properties include access to wifi

Destinations to explore