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Boutique hotel vacation rentals in Antioquia

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Antioquia

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Guest favourite
Hotel room in Medellín
5 out of 5 average rating, 7 reviews

Room with 2 beds (double + twin), private bathroom and breakfast

Double + Twin Room – spacious, bright and with a renovated colonial style. Private bathroom and 15 m² area + 2 m² bathroom. Ideal for families, couples, and digital nomads looking for comfort and cultural connection: Co-working area with high-speed internet. Interior patio with vegetation, TV room, shared dining room and equipped kitchen. Breakfast every morning. Enjoy a fresh, natural, and quiet experience in the heart of Medellín's tourist area, just steps from the metro, restaurants, and bars.

Superhost
A modern suite features a spacious bed against a backdrop of elegant textures. Natural light floods the area through large glass doors, which lead to a private balcony. A jacuzzi is positioned beside the bed, with a small dining table nearby. A wall-mounted Smart TV enhances the room's amenities.
Hotel room in Medellín
4.61 out of 5 average rating, 38 reviews

Balcony-Jaccuzzi-Breakfast-3 connecting bedrooms

The Imperial Suite is a 3-bedroom connecting suite, with luxurious queen-size beds allowing 6 guests to stay together. With jacuzzi, balcony and kitchen in the main bedroom, and, like all of our boutique luxury rooms, features an en-suite bathroom, HD smart TV, A/C, mini-bar and secure key card access. Additional services include full breakfast, daily cleaning, 24-hour reception, and access to our rooftop heated chlorine-free salt water swimming pool and bar. By Haven, a design hotel.

Guest favourite
A spacious corridor features a large, suspended green plant, enhancing the airy feel. Natural light filters through the surrounding walls, illuminating wooden benches and a decorative piece. The layout invites relaxation and connects to the surrounding areas, leading to balconies and shared spaces.
Hotel room in Puerto Berrío
4.74 out of 5 average rating, 43 reviews

Affordable and comfortable rooms in Puerto Berrio

Hotel Tayrona is a small family hotel where you will find a warm and very familiar service. We offer 24-hour reception service, free Wi-Fi connection, and large open areas for your comfort. Our rooms are modestly furnished. Every room is fully furnished with a TV, work desk, private bathroom and air conditioning and/or fan. We have large terraces and balconies with views of the city. And the wide open-air corridors and shared lounges allow you to enjoy a fresh and familiar atmosphere.

Superhost
Hotel room in Medellín
4.84 out of 5 average rating, 32 reviews

Room+WiFi+Jacuzzi+Tv+Work Area+Laundry @Medellín

✔️SuperAnfitrion Verificado! Tu estadía estará en las mejores manos 🛏️ Habitación en Hotel UKU INN, Medellín, Colombia 🇨🇴 Excelente ubicación cerca de restaurantes, centros comerciales y lugares turísticos. ✅ Perfecto para turistas, ejecutivos o parejas 👨‍👧‍👧 Dotado con todo lo necesario, sábanas, toallas, productos de limpieza 🛏️ El hotel boutique ofrece: 🌊Jacuzzi 🌞Solarium 📶WiFi 🔒 Seguridad 🔥Agua Caliente 👕Lavadora 📺Tv 💻Zona de trabajo

Superhost
A modern bedroom features a spacious bed with crisp white linens. A flat-screen television is mounted on the wall, while a small refrigerator and a wooden bench add functionality. Natural light enters through a window, enhancing the room's fresh and clean design.
Hotel room in Medellín
4.7 out of 5 average rating, 10 reviews

Deluxe Double Room with hot tub Origen Hotel

Perfect location in Parque Lleras for you to have a great time in Medellín! At the center of it all. The hotel is nearby the best restaurants, bars and night clubs the city has to offer Located in Poblado, Medelin's hottest and trendiest neighborhood. Perfect place to have your party time! Origen will offer you the coziness you'd expect from home, in a more exotic setting. Posh interior décor. Glitzy bathroom. Lavish dreams await.

Guest favourite
A light-filled bedroom features a spacious bed with dark pillows and a simple decorative tree on the wall. A desk with a chair is positioned near a large window, providing a view of outdoor greenery. Air conditioning is installed for temperature control.
Hotel room in Medellín
4.83 out of 5 average rating, 126 reviews

Laureles ✦Wifi-200MB✦, Loros Experience, Aire ac.

Comfortable room that will make you want to stay longer. Experience the excitement and beauty of parrots and birds without having to leave the accommodation. Enjoy the views and weather of Medellín sitting on the balcony while the city lights illuminate your eyes. If you stay with us you can connect with nature and enjoy its charms in our themed parrot rooms, learning from them by seeing and listening to them in the surroundings.

Superhost
A modern, two-story building is presented, featuring a minimalist exterior with large windows and a black garage door. The facade is primarily white, complemented by a patterned paving in front. Surrounding trees provide shade, while colorful windows from a neighboring building add visual interest.
Hotel room in Medellín
5 out of 5 average rating, 3 reviews

Boutique Hotel - Light Laureles Room 201

- Rooms with private bathroom and balcony, SmarTV, safe and air conditioning, fiber optic WiFi - Shared social areas such as kitchen, work area and laundry and drying area - The comfort of the rooms is designed to enjoy a stylish experience in this centrally located accommodation, neighbor of the exclusive Laureles area, shopping centers, stadium, bullring, metro stations, among many other strategic options of your stay.

Top guest favourite
Hotel room in Medellín
5 out of 5 average rating, 14 reviews

I - Suite in Boutique Hotel in El Poblado

Welcome to Casa ROMERO EN FLOR, where Nature, Art and Literature meet. Discover an oasis in the heart of Medellín. Our private suite is located in a boutique hotel, gallery and bookstore, with charming architecture, with only 3 exclusive rooms for our guests, surrounded by nature, mosaic art and a selection of second-hand books, so you can lose yourself - and find yourself - among pages, plants and works of art.

Guest favourite
A comfortable bed is positioned by a large window, offering views of the surrounding greenery and urban landscape. Two outdoor chairs are visible on the balcony, surrounded by sheer curtains that let in natural light.
Hotel room in Medellín
4.97 out of 5 average rating, 94 reviews

Room with balcony and breakfast for 2 people

The Lettera Hotel is located in the exclusive El Poblado sector of Medellín. In a residential sector and a few minutes walk from Provenza, one of the fastest growing gastronomic and entertainment areas in the city, near Lleras Park. We have comfortable rooms equipped with Smart TV, Safe, Minibar, desk, amenities and more that will make you feel at home. At Lettera Hotel we write stories, come and live yours!

A spacious outdoor pool is surrounded by lounge chairs and umbrellas, with vibrant tropical plants and palm trees in the background. Soft lighting from string lights creates a relaxed atmosphere as the evening sky transitions to dusk.
Hotel room in Santa Fe de Antioquia
4.83 out of 5 average rating, 48 reviews

Deluxe Suite with hot tub

We are a hotel house located in the historic center of Santa Fe de Antioquia that offers comfort and rest, with an excellent atmosphere, comfortable rooms and a large wet area. Ideal for couples looking to sunbathe and experience the culture of a colonial village.

Guest favourite
A private villa features an open-plan layout, with expansive glass doors connecting the indoors to an outdoor area. A small pool is situated beside a sleek seating arrangement, while verdant plants enhance the serene atmosphere.
Hotel room in Obregon
5 out of 5 average rating, 11 reviews

Villa3 with Pool Arde La Selva

Private villa with Roman pool located in a luxury hotel. Wet areas, restaurant and bar. A la carte breakfast included. Amenities South Loto and high quality lingerie. Wifi available in all areas. A/C in all bedrooms. King bed and open-air shower.

Superhost
Hotel room in Medellín
4.67 out of 5 average rating, 3 reviews

Hotel Room with King-Size Bed and Breakfast

Habitación de 23 Mt2 con cama King, para 2 personas. Tiene aire acondicionado, secador de pelo, plancha, baño privado con ducha, pisos de madera, caja fuerte, wifi de cortesía y muchas más facilidades.

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