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Guesthouse vacation rentals in Frederick County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouses in Frederick County
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Frederick County guesthouses
Family-friendly guesthouses
![](https://a0.muscache.com/im/pictures/161b0cb2-33c0-4af1-8701-a5d09a90403f.jpg?im_w=720)
Guest favourite
Guesthouse in Middletown
4.95 out of 5 average rating, 259 reviewsIndulge, Fresh Flowers, Frederick County Haven
![](https://a0.muscache.com/im/pictures/b0695245-98c2-4d67-abdc-8580fdc2b16e.jpg?im_w=720)
Guest favourite
Guesthouse in Frederick
4.97 out of 5 average rating, 322 reviewsThe Shady Bear Cabin
![](https://a0.muscache.com/im/pictures/6b376b6c-a166-47ac-b379-ee85db3b26d9.jpg?im_w=720)
Guest favourite
Guesthouse in Smithsburg
4.97 out of 5 average rating, 670 reviewsJewel Vinsota Artist's Guesthouse
![](https://a0.muscache.com/im/pictures/1bd2a8e0-b58c-4f41-8958-4e295cd43f07.jpg?im_w=720)
Guest favourite
Guesthouse in Frederick
4.98 out of 5 average rating, 165 reviewsPool and Heated Spa Open April 1st
![](https://a0.muscache.com/im/pictures/6d039e60-dd70-4263-8e9a-a8ff8b3513ca.jpg?im_w=720)
Guesthouse in Frederick
4.87 out of 5 average rating, 30 reviewsThe Wander Inn
Guesthouses with a patio
![](https://a0.muscache.com/im/pictures/miso/Hosting-949183109195351383/original/55aecc1f-fd60-4b64-91a5-763e6f9505e9.jpeg?im_w=720)
Guesthouse in Middletown
Simple gestures
![](https://a0.muscache.com/im/pictures/eb664ea5-ab25-4426-99de-384dbc4a5c3a.jpg?im_w=720)
Guest favourite
Guesthouse in Lovettsville
4.94 out of 5 average rating, 140 reviewsThe Patent House
![](https://a0.muscache.com/im/pictures/51450925-9afc-445b-90be-68ad2a644bb0.jpg?im_w=720)
Guest favourite
Guesthouse in Myersville
4.93 out of 5 average rating, 210 reviewsSpruce Run Cottage, Farm stay on Catoctin Mountain
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Guest favourite
Guesthouse in Mount Airy
4.98 out of 5 average rating, 90 reviewsTreasured Hideaway on the Hill
Guesthouse rentals with a washer and dryer
![](https://a0.muscache.com/im/pictures/6b376b6c-a166-47ac-b379-ee85db3b26d9.jpg?im_w=720)
Guest favourite
Guesthouse in Smithsburg
4.97 out of 5 average rating, 670 reviewsJewel Vinsota Artist's Guesthouse
![](https://a0.muscache.com/im/pictures/51450925-9afc-445b-90be-68ad2a644bb0.jpg?im_w=720)
Guest favourite
Guesthouse in Myersville
4.93 out of 5 average rating, 210 reviewsSpruce Run Cottage, Farm stay on Catoctin Mountain
![](https://a0.muscache.com/im/pictures/161b0cb2-33c0-4af1-8701-a5d09a90403f.jpg?im_w=720)
Guest favourite
Guesthouse in Middletown
4.95 out of 5 average rating, 259 reviewsIndulge, Fresh Flowers, Frederick County Haven
![](https://a0.muscache.com/im/pictures/1bd2a8e0-b58c-4f41-8958-4e295cd43f07.jpg?im_w=720)
Guest favourite
Guesthouse in Frederick
4.98 out of 5 average rating, 165 reviewsPool and Heated Spa Open April 1st
![](https://a0.muscache.com/im/pictures/82ab429c-8f31-4e65-94e8-0c039263e406.jpg?im_w=720)
Guest favourite
Guesthouse in Frederick
5 out of 5 average rating, 235 reviewsThe Carriage House at Hessian Overlook, Downtown
![](https://a0.muscache.com/im/pictures/miso/Hosting-978870930073295977/original/1ae1e4a5-4f5d-494e-91a4-9dda50de1d20.jpeg?im_w=720)
Guest favourite
Guesthouse in Lovettsville
5 out of 5 average rating, 10 reviewsThe Tuberose Suite
![](https://a0.muscache.com/im/pictures/airflow/Hosting-31385664/original/b80ab0ef-fcc3-4b07-b740-8447d4021d1f.jpg?im_w=720)
Guest favourite
Guesthouse in Frederick
5 out of 5 average rating, 83 reviewsA Quiet Haven
![](https://a0.muscache.com/im/pictures/miso/Hosting-784456008908189339/original/fa72f1fb-fa20-4380-bd84-14a301e7b9f8.jpeg?im_w=720)
Guest favourite
Guesthouse in Mount Airy
4.98 out of 5 average rating, 90 reviewsTreasured Hideaway on the Hill
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