
House vacation rentals in Guadalupe
Find and book unique houses on Airbnb
Top-rated house rentals in Guadalupe
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Guadalupe house rentals
House rentals with a pool

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

Spacious 4bd Home w/ Pool, Spa + Pet Friendly!

San Luis Obispo House With Pool And Hot Tub

Getaway at the Highlands+Heated Pool+Hot Tub

FairView Lavender Estate

Ranch Style Home w/ Bikes! Heart of Wine Country

Luxury Mountain View Retreat Pool/jacuzzi
Weekly house rentals

Windermere Villa-Jacuzzi, Ocean Views,Ping Pong

Steps to the Beach! Rooftop Deck! Firepit & BBQ!

Luxury Surfhouse 5Min to Pismo Walk to Restaurants

Great little beach house. County License# 6012116

Cozy Studio Close to Downtown SLO

Coastal cottage in Pismo beach

Shore To Please Beach House Oceano Pismo Avila SLO

Farmhouse located on San Luis Obispo Central Coast
Private house rentals

Entire Home - Luxurious California Coastal Retreat

Happyfam Country Home Near Coast

Coastal Retreat - Sauna, Fire Pit & Outdoor Lounge

Back Bay Getaway - Dog Friendly - Home in Los Osos

Home, comfortable to rest and relax. Welcome

Beautiful, Spacious Home 3 Miles from Pismo Pier

Luxurious Santa Ynez Valley wine country cottage

Central Coast Gem (Orcutt)
Destinations to explore
- Southern California Vacation rentals
- Los Angeles Vacation rentals
- Stanton Vacation rentals
- Northern California Vacation rentals
- San Diego Vacation rentals
- Channel Islands of California Vacation rentals
- San Francisco Bay Area Vacation rentals
- San Francisco Vacation rentals
- Gold Country Vacation rentals
- Central California Vacation rentals
- Palm Springs Vacation rentals
- San Francisco Peninsula Vacation rentals
- Cayucos Beach
- Captain State Beach
- Montaña de Oro State Park
- Cayucos State Beach
- Natalie's Cove
- Gaviota Beach
- Arroyo Quemada Beach
- Morro Strand State Beach
- B & E Vineyard & Winery
- Refugio Beach
- Dairy Creek Golf Course
- Mission San Luis Obispo de Tolosa
- Morro Rock Beach
- Seal Beach
- Pismo State Beach
- Sand Dollars
- Olde Port Beach
- Bianchi Winery
- Point Sal State Beach
- Paradise Beach
- Pirates Cove Beach
- Spooner's Cove
- Baywood Park Beach
- Morro Bay Golf Course