House vacation rentals in Guadalupe

Find and book unique houses on Airbnb

Top-rated house rentals in Guadalupe

Guests agree: these houses are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Top guest favourite
The exterior of a modern single-level home is framed by lush greenery and decorative stones. A smooth pathway leads to a wooden front door, while a mature tree provides shade in the front yard. The garage features a sleek, contemporary design.
Home in Arroyo Grande
4.99 out of 5 average rating, 159 reviews

Luxury Surfhouse 5Min to Pismo Walk to Restaurants

Modern open-air retreat, minutes from Pismo Beach and walking distance to restaurants, shops, coffee and entertainment. Bright and spacious, our Airbnb was carefully designed for comfort and connection, wrapped in a coastal luxury vibe. Families love the surf lounge, games, fire pit, and beach gear. Our one-of-a-kind Airbnb is fully stocked with everything you need, making your stay relaxing and stress-free. With a short drive to SLO or Avila, your next unforgettable coastal getaway begins here.

Guest favourite
The manicured garden features neatly trimmed hedges and a brick-laid patio. White metal chairs and tables are positioned among various plants and flower pots, creating serene sitting areas. The Victorian house is visible in the background, framed by lush greenery.
Home in Lompoc
4.95 out of 5 average rating, 331 reviews

1879 Victorian in Central Coast Wine Country

Lovely private 1879 Victorian built by Lompoc founder W.W. Broughton - with fully stocked kitchen, living room/ dining room, laundry room, full bathroom, back yard (lawn mowed Tuesdays, watering/ gardening is done generally in the mornings, cable TV, internet, set in spacious, beautifully manicured Victorian Gardens. Reservation includes two bedrooms with queen beds. Note: Entrance stairs may be difficult for those with limitations. No pets. Two triplexes with six renters are also on property.

Superhost
The private patio is illuminated by string lights, creating a cozy ambiance at night. A fire pit, centered on a wooden table, casts a warm glow. Comfortable seating is provided by two armchairs, accentuated by decorative pillows, with potted plants enhancing the serene environment.
Home in Grover Beach
4.89 out of 5 average rating, 226 reviews

*Golf*Private Patio*Perfect Location*Fire Pit*BBQ

⭐Bring your family and come soak up the California sun in this Central Coast Retreat! ⭐ ⭐"I'd highly recommend a stay at the Sandy Feet Retreat!"⭐ 👉 Fenced in Private Patio 👉 Fire Pit 👉 Memory Foam on all beds 👉 Smart TV with all Apps 👉 BBQ 👉 King Bed 👉 442Mbps ⭐ Located far enough from town to relax away from the crowds but close enough to walk to the beach or drive to: 👉Pismo Dunes-5 min 👉Monarch Butterflies-3min 👉Pismo Beach-7min 👉Pismo Golf Course-4min 👉Avila Valley Farm-9min

Guest favourite
A cozy bedroom features a spacious bed adorned with decorative pillows. A striped hammock chair is suspended beside the bed, providing a comfortable spot for reading or relaxation. Soft natural light enters through the window, emphasizing the serene color palette.
Home in Arroyo Grande
4.93 out of 5 average rating, 340 reviews

Beach-themed farmhouse with indoor fireplace

As 13-time Superhosts- we welcome you to the perfect place to relax & unwind after your day. This stylish and spacious home offers a sunny deck, surrounded by trees for sunbathing or watching the sunset. The huge 2nd bdrm is a great place for reading in our hammock chair or for a quiet work space. Downstairs the fully equipped kitchen has everything you need for cooking meals. Outdoor patio is a nice place to bbq & relax as you listen to the hawks, owls, & other birds in this country setting.

Guest favourite
A sunset sky filled with vibrant colors casts a warm glow over the country house. The exterior is highlighted by large windows and a welcoming entrance. The driveway leads towards the home, bordered by manicured landscaping, set against a backdrop of rolling hills.
Home in Arroyo Grande
4.83 out of 5 average rating, 281 reviews

Coastal Getaway, Country House, near 101 FWY

Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Superhost
A large seashell rests on the sandy beach, partially submerged in gentle ocean waves. The clear blue water extends to the horizon, meeting a vibrant sky with scattered clouds, creating a serene coastal view.
Home in Oceano
4.85 out of 5 average rating, 585 reviews

Shore To Please Beach House Oceano Pismo Avila SLO

A complete downstairs beach house with a kitchen, living room, relaxing bedroom, smart TVs, backyard, BBQ, bikes & a game room- Unlimited Vehicle Pass to Dunes - 1 mile to beach - 3/4 mile to Enormous kids park - Restaurants within walking distance - Netflix - Boll & Branch bedding - 5-8 minute drive to Pismo, Grover Beach, & Arroyo Grande - Near Avila beach, Shell beach & San Luis Obispo - 20 min drive to Cayucos & Morro Bay. DropMyPin for complete amenities & pictures.

Top guest favourite
A living area is shown with a sectional sofa arranged around a coffee table. Large windows provide natural light and offer views of the outdoor space. A clock is mounted on the wall, accompanied by decorative accents, while a door leads to the outdoor patio.
Home in Nipomo
4.97 out of 5 average rating, 106 reviews

Pleasant hills, king suite, EV Charger

Come relax and enjoy our peaceful home and outdoor spaces. We are located halfway between Los Angeles and San Francisco. Here you can experience the beautiful Central Coast including wineries, Beaches, Cal Poly and golf courses. We are located in a quiet neighborhood adjacent to an organic blackberry farm. Easy access to the 101 Freeway, where you can easily visit Santa Barbara or Paso Robles wine regions. Our home is FULLY Air Conditioned for your comfort.

Guest favourite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 344 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Top guest favourite
The open living area features wood-look flooring, a ceiling fan, and large windows allowing natural light. A comfortable seating arrangement includes a dark sofa and chairs, alongside a wooden coffee table. Decorative plants and fresh flowers add a touch of greenery to the space.
Home in Oceano
4.95 out of 5 average rating, 134 reviews

Spacious Whole Residence w/ Bikes--Close to Beach!

Single story 3bd/2ba home in a quiet informal neighborhood ~ 1.5 miles (30 min walk/10 min bike ride) to the beach. Full Kitchen, Washer/Dryer, Indoor Grill, Outdoor Grill, Waffle Iron, Pressure Cooker/Slow Cooker, Dutch Oven, Mixer, Blender, Bicycles w/Locks & Helmets, Wifi, Smart Tv's (in every bedroom and in the living room) and a Stand/Sit Desk with Computer, Printer/Fax/Scanner, plus other amenities...

Guest favourite
A bright living room is presented with natural light streaming through a window. Two comfortable chairs with soft throw blankets face a modern TV mounted on a pale wall. Decorative plants enhance the space, complemented by a wooden coffee table and light hardwood flooring.
Home in Arroyo Grande
4.93 out of 5 average rating, 228 reviews

Mid-century home in the heart of Arroyo Grande.

Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Top guest favourite
A contemporary home is highlighted with expansive glass doors, allowing views of the surrounding landscape. A wooden dining table is shown, adorned with a sunflower. The deck extends along the residence, featuring comfortable seating areas.
Home in San Luis Obispo
4.95 out of 5 average rating, 125 reviews

Sanctuary on Sunset Ridge ~ Panoramic Ocean Views

Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge

Top guest favourite
A spacious home is set against a clear blue sky, surrounded by lush trees and flowering plants. The well-maintained yard features a gravel pathway leading to a large patio area, offering ample space for outdoor relaxation and gatherings.
Home in Nipomo
4.97 out of 5 average rating, 107 reviews

Beach, Wine Country, & Golf adjacent home for 8

Full home privacy, with a backyard to properly relax in after a day spent exploring the beautiful Central Coast. Enjoy the quiet of Nipomo in this country living style home. Pour some wine, light up the fire pit, toss some horseshoes, and kick back at Tejas Place!

Popular amenities for Guadalupe house rentals