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Vacation rentals in Lake City

Vacation rentals in Lake City

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Lake City

Guests agree: these stays are highly rated for location, cleanliness, and more.

  • Home Away from Home Apt. 8 - Family Suite
    SUPERHOSTEntire apartment · 4 guests · 2 beds · 1 bath
    Home Away from Home Apt. 8 - Family Suite

    Located on Main Street in a family home that has been updated to be like brand new. Two private bedrooms, with private entrance, one full bath. Back BR has a full size bed, TV, dressing area and closet . Front BR has queen bed, TV, microwave, full size refrigerate, closet and dining table. Amenities include 2 CABLE & Roku TV's, wifi, front door parking, fresh brewed coffee,CAFE VALE. Up town Lake City is an easy one mile walk along Main Street. Hablamos Español 1/2 way from New York to Miami.

    What guests are saying:

    “I loved the layout and Southern Hospitality. It's so close to all the great Fast Foods, Store's and safe. I can say the layout and cleanliness was so well done you hey you're money worth. This was my first Airbnb and it gave me a home from home being all the way from Maryland and being in a new town I felt Love and Compassion from a perfect stranger now Friend. I was informed of where everything is located and greater with a Friendly Smile. I would definitely recommend this airbnb and I definitely appreciate the compassion shown”

  • Cute one story historic home
    SUPERHOSTPrivate room · 4 guests · 2 beds · 1 private bath
    Cute one story historic home

    Extra large wood paneled room with a private bath and separate entrance. Quiet neighborhood with a park across the street and is walking distance to downtown.

    What guests are saying:

    “This was my second time staying at Marilyn and George's house, and just like the first time, they did not disappoint. They were VERY hospitable, and their place was clean and comfortable. They're such nice people that I'm planning on revisiting Lake City just to spend time with them. Highly recommend!”

  • Cozy Poolside Cottage- Near I-95 & I-20, Florence
    SUPERHOSTEntire guesthouse · 4 guests · 2 beds · 1 bath
    Cozy Poolside Cottage- Near I-95 & I-20, Florence

    The pool house is a great stopping place for weary travelers ready to relax and the perfect gathering place for those who are spending time in Florence/Darlington. Located in a quiet neighborhood 5 min off of I95 and I20, you will enjoy the setting with palm trees, pool and outdoor fire pit. A queen bed, shower, bathroom, queen sleeper sofa, wifi and TV all await.

    What guests are saying:

    “We loved staying overnight at the cozy pool side cottage! It was the perfect respite for our family traveling down 95. We got in without issue due to host’s excellent communication and wasted no time in getting in the pool and playing after a long day in the car. The cottage was thought fully furnished and we slept peacefully before heading on our way. Will definitely be back to this clean and cute property on future travels! Highly recommend.”

Vacation rentals for every style

Get the amount of space that is right for you.

  • Homes
  • Hotels
  • Unique stays

Popular amenities for Lake City vacation rentals

  • Kitchen
  • Wifi
  • Pool
  • Free parking on premises
  • Air conditioning

Other great vacation rentals in Lake City

Private Boho Guest House - Florence/Near  95
SUPERHOSTEntire guesthouse
Private Boho Guest House - Florence/Near 95
Price:$112 CAD/night
Marlboro Suites Apt B
Entire condominium
Marlboro Suites Apt B
Price:$121 CAD/night
*Relax and Refresh Cottage-Near I-95 and Florence*
SUPERHOSTEntire cottage
*Relax and Refresh Cottage-Near I-95 and Florence*
Price:$133 CAD/night
Private Bath, plus a light continental breakfast
SUPERHOSTPrivate room
Private Bath, plus a light continental breakfast
Price:$100 CAD/night
Your home away from home!
Private room
Your home away from home!
Price:$129 CAD/night
Casa De Sotavento
SUPERHOSTPrivate room
Casa De Sotavento
Price:$130 CAD/night
Craft house Apt B
Private room
Craft house Apt B
Price:$61 CAD/night
The Cottage at Double C Farm
SUPERHOSTFarm stay
The Cottage at Double C Farm
Price:$102 CAD/night
Hide Away Studio Apartment
Entire guesthouse
Hide Away Studio Apartment
Price:$61 CAD/night
5-Star Cozy Queen in Florence, SC
SUPERHOSTPrivate room
5-Star Cozy Queen in Florence, SC
Price:$81 CAD/night
Night shift travel nurse oasis!
early check in ok!
Private room
Night shift travel nurse oasis! early check in ok!
Price:$41 CAD/night
Cute 4BR Bungalow Near Downtown
Entire house
Cute 4BR Bungalow Near Downtown
Price:$54 CAD/night
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