
Vacation rentals in Panama Canal
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Panama Canal
Guests agree: these stays are highly rated for location, cleanliness, and more.

Comfortable and spectacular old town - parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Gamboa Toucan Apartment casa # 126
Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Panama Canal View • King Bed • Walk to Casco Viejo
✨Welcome to apartment 805 with a private balcony and Stunning View of Famous Panama Canal where ships line up ✨ 📍Located on the 8th floor in the modern PH Casco View building steps away (250m) from the vibrant Panama City historic heart Casco Viejo (also called Casco Aniguo) ✨One bedroom unit (58 m² / 624 ft²) offers: - Cozy king-size bed with A/C & 55” Smart TV - Stylish living room with 55” Smart TV & air conditioning - Fully equipped kitchen - Modern bathroom - Washer/dryer

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Large Apartment in La Cuadra - Casco | By Alura
El Casco Antiguo de Panamá es uno de los barrios más encantadores y vibrantes de la ciudad. Declarado Patrimonio de la Humanidad por la UNESCO. El Apartamento El espacio combina líneas modernas con detalles originales del barrio. Cuenta con una distribución luminosa, cocina equipada, sala amplia y acabados pensados para brindar comodidad. Posee un dormitorio con cama king y un hermoso balcón. Es ideal para quienes buscan vivir una experiencia auténtica en el Casco Antiguo.

Gorgeous Flat in the best location in Casco Viejo
This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Jacuzzi & Private Rooftop recently refurbished D11
Welcome to Casa Diez, the most romantic spot in the Old Town! Enjoy a unique experience in this room for two, featuring an exclusive outdoor Jacuzzi overlooking the starry sky. Relax in a comfortable queen-size bed, with a private bathroom, air conditioning, Smart TV, and Wi-Fi. You'll also have access to a beautiful shared pool and laundry center, exclusively for our guests. Enjoy an unforgettable stay in a cozy, intimate, and fully equipped setting.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Cozy Studio in Cinta Costera with Home Vibes
✨ Vive la experiencia “Cinta Costera Vibes” 🌴 desde este moderno apartaestudio con vista panorámica a la Bahía y a la vibrante Avenida Balboa. Perfecto para viajeros que buscan confort, estilo y ubicación premium. Disfruta piscina, restaurante, gimnasio y rooftop con el mejor atardecer de Panamá 🌅. Ideal para estancias cortas o largas — tu hogar con calor de hogar y toque 5⭐. ¡Guárdalo como favorito y vive la experiencia Host Up!

Modern apartment in the Historic Center
I invite you to this apartment in La Manzana, Santa Ana. This place has a strategic location - it will be very easy to plan your visit! It is only 2 minutes walking from Casco Viejo. Our studio offers an ideal location to enjoy the Casco and the entire city. We have Wifi, hotel bed, fully equipped kitchen, working space, TV and hot shower. In addition, the building has 24 hour security so you have nothing to worry about!!

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

King Bed, Creative Design Steps from Casco Viejo
Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.
Popular amenities for Panama Canal vacation rentals
Other great vacation rentals in Panama Canal

Best location & Rooftop Pool Apto with elevator

Luxury apartment in the heart of Panama

Malambo Inn, Santa Ana-Casco

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Casco Viejo Loft • Rooftop Pool + Gym & Balcony

Tiny House in the Nature by HYTTE HOMES

Modern skyscraper, free breakfast, pool, gym

CASA SAEMA "C" -Design Apt, Casco Viejo Panama
Destinations to explore
- Rentals with an EV charger Panama Canal
- Rentals with an accessible height bed Panama Canal
- Serviced apartment rentals Panama Canal
- Apartment rentals Panama Canal
- Rentals with a sauna Panama Canal
- Hostel rentals Panama Canal
- Bed and breakfasts Panama Canal
- Rentals with breakfast Panama Canal
- Loft rentals Panama Canal
- Condo rentals Panama Canal
- Rentals with a washer and dryer Panama Canal
- Pet-friendly rentals Panama Canal
- Rentals with outdoor seating Panama Canal
- Rentals with a patio Panama Canal
- Family-friendly rentals Panama Canal
- Fitness-friendly rentals Panama Canal
- Private suite rentals Panama Canal
- Guesthouse rentals Panama Canal
- Rentals with a home theater Panama Canal
- Waterfront rentals Panama Canal
- Rentals with a firepit Panama Canal
- Boutique hotels Panama Canal
- Rentals with beach access Panama Canal
- Hotel rooms Panama Canal
- Rentals with pools Panama Canal
- Rentals with a kayak Panama Canal
- Rentals with lake access Panama Canal
- Beachfront rentals Panama Canal
- House rentals Panama Canal
- Rentals with a hot tub Panama Canal
- Smoking-friendly rentals Panama Canal
- Things to do Panama Canal
- Sightseeing Panama Canal
- Tours Panama Canal
- Art and culture Panama Canal
- Food and drink Panama Canal
- Nature and outdoors Panama Canal
- Sports activities Panama Canal
- Things to do Panama
- Art and culture Panama
- Sports activities Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama
- Entertainment Panama
- Food and drink Panama




