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Vacation rentals in Panama Canal

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Top-rated vacation rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favourite
Apartment in Panamá
4.98 out of 5 average rating, 221 reviews

Comfortable and spectacular old town - parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Top guest favourite
Apartment in Panamá
4.96 out of 5 average rating, 25 reviews

Modern apartment in the heart of Obarrio

This apartment stands out for its privileged location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The convenience of having two bathrooms makes it unique. Ideal for travelers looking for peace of mind and functionality. Located a few steps from 50th Street and the iconic El Tornillo building. You're surrounded by casinos, hotels, and restaurants. Safe area for walking and enjoying the city.

Guest favourite
A modern living area features a plush area rug underneath a glass coffee table, which displays decorative items and books. A flat-screen TV is mounted on a marble accent wall, and elegant dining furniture is visible in the background, creating a sophisticated and inviting atmosphere.
Apartment in Panamá
4.87 out of 5 average rating, 38 reviews

Cozy Designer Stay at Yoo & Arts Panama

Experience an elegant, modern apartment with the and comfort that makes you feel right at home from the start. Located on the prestigious Avenida Balboa, in the iconic Yoo Panama & Arts Tower, this space blends designer style with unbeatable comfort. You'll be surrounded by top-rated restaurants, shopping centers, and just minutes from the historic charm of Casco Viejo — the city's most iconic neighborhood. Perfect for travelers who value great design, location, and an unforgettable stay. 🏙️✨

Top guest favourite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guesthouse in Gamboa
4.94 out of 5 average rating, 78 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Top guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Apartment in Panamá
5 out of 5 average rating, 57 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Superhost
Apartment in Panamá
5 out of 5 average rating, 5 reviews

Large Apartment in La Cuadra - Casco | By Alura

El Casco Antiguo de Panamá es uno de los barrios más encantadores y vibrantes de la ciudad. Declarado Patrimonio de la Humanidad por la UNESCO. El Apartamento El espacio combina líneas modernas con detalles originales del barrio. Cuenta con una distribución luminosa, cocina equipada, sala amplia y acabados pensados para brindar comodidad. Posee un dormitorio con cama king y un hermoso balcón. Es ideal para quienes buscan vivir una experiencia auténtica en el Casco Antiguo.

Guest favourite
Apartment in Panamá
4.93 out of 5 average rating, 14 reviews

VIP Suite/ Sea View + gym and Pool & Sky Lounge

Elegant studio suite with stunning ocean views, located on Panama city iconic Cinta Costera. Ideal for business travelers, couples, or tourists seeking style, comfort, and convenience. Features a full kitchen, spacious bathroom, fast Wi-Fi, and washer/dryer. Enjoy top amenities: pool, gym, sky lounge, game room, restaurants, and 24/7 security. Hosted with care by César & Claudia to ensure a warm and memorable stay in Panama . Remember to check our Guide. With parking include !

Top guest favourite
Apartment in Panamá
4.94 out of 5 average rating, 16 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favourite
Apartment in Panamá
5 out of 5 average rating, 10 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favourite
A modern studio apartment features a spacious bed with a backdrop of black and white walls. A flat-screen TV is mounted on the wall opposite a comfortable seating area and a round coffee table. Geometric floor tiles include shades of blue, enhancing the contemporary ambiance.
Apartment in Panamá
4.9 out of 5 average rating, 41 reviews

Modern apartment in the Historic Center

I invite you to this apartment in La Manzana, Santa Ana. This place is strategically located - it will be very easy to plan your visit! It is only a 2-minute walk from the Old Town. Our studio offers an ideal location to enjoy the Historic District and the entire city. We have Wi-Fi, a hotel bed, a fully equipped kitchen, a space to work, a TV, and a hot shower. In addition, the building has 24 hour security so you have nothing to worry about!!

Guest favourite
An outdoor pool area is featured with modern sun loungers surrounding the illuminated water. Lounge furniture provides space for relaxation, while the skyline of the city is visible in the background against a twilight sky.
Condo in Panamá
4.94 out of 5 average rating, 64 reviews

Modern and luxurious Costera Cinta

Experience the luxurious PH Yoo experience with city views in this elegant apartment with king bed and floor-to-ceiling windows. Enjoy upscale amenities: swimming pool, gym, squash court, spa, and more. Privileged location close to tourist areas, restaurants, bars and malls. Inside the building there are gastronomic options with exclusive discounts and free valet parking. Modern, spacious and sophisticated space for an unforgettable getaway.

Superhost
Apartment in Panamá
5 out of 5 average rating, 3 reviews

Cozy Studio in Cinta Costera with Home Vibes

✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

Popular amenities for Panama Canal vacation rentals

Destinations to explore

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