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Vacation rentals in Panama

Find and book unique accommodations on Airbnb

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Top-rated vacation rentals in Panama

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favourite
Treehouse in Isla Colon
Secret Jungle Treehouse by the Sea
This is 1 of our 2 treehouses: 2 bedrooms; built around a huge tree overlooking the lush jungle in a hidden setting. Artistically designed & comfortable; welcoming romantic souls, nature lovers & the adventurous. Enjoy nature in the harmony of an eco environment; ocean breezes, sound of waves, birds & monkeys. Spectacular sandy beaches only steps away. Surf, swim, bike, explore & live the adventure!. (2nd TREEHOUSE: https://www.airbnb.com/rooms/19376873? YouTube « Jungle Treehouse by the sea »
May 20 – 27
$354 CAD per night
Superhost
Earth homes in El Cope, Penonome
Beautiful Eco House in Panama
We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.
Jun. 20 – 27
$297 CAD per night
Guest favourite
Home in Playa Venao
Beautiful Home Directly on Playa Venao Sleeps 8-10
This is our personal home and we take good care to make sure you thoroughly enjoy your stay! This home is located on the best surfing beach in the entire country. Walk out of your back door onto the sandy beach filled with wildlife and the best beach break for beginners to pros. This home offers luxury accommodations. This home is for families and respectful renters only. We do not accept groups who want to use the home to party.
Jul. 23 – 30
$884 CAD per night

Popular amenities for Panama vacation rentals

Other great vacation rentals in Panama

Guest favourite
Hut in Cristóbal Island
Cocovivo Dolphin Pod
Nov. 6 – 13
$143 CAD per night
Guest favourite
Home in Taboga Island
Casa Rosie - Taboga dream home
Jun. 6 – 13
$332 CAD per night
Guest favourite
Townhouse in Panama
Unique Historic House in Casco
Aug. 8 – 15
$889 CAD per night
Superhost
Bungalow in Bocas del Toro
Romantic Over the Water Bungalow with Floating Bed
May 16 – 23
$185 CAD per night
Guest favourite
Cabin in Torio
Cozy open space, unique jungle views, river access
Jan. 24 – 31
$165 CAD per night
Superhost
Villa in Bocas del Toro
Bocas del toro - Villa over the water- Bahia Coral
Aug. 15 – 22
$565 CAD per night
Guest favourite
Home in Playa Venao
Casa Samambaia - sea view tropical paradise w pool
Jun. 28 – Jul. 5
$396 CAD per night
Superhost
Cottage in Bocas del Toro District
Las Casitas of Villa Paraiso | Beachfront & Pool
Oct. 21 – 28
$370 CAD per night
Guest favourite
Apartment in Panama City
Jacuzzi inside colonial ruins in beautiful apartme
Jul. 27 – Aug. 3
$268 CAD per night
Guest favourite
Cottage in Panamá
Modern House in Altos de Cerro Azul with 2 rooms
Apr. 4 – 11
$187 CAD per night
Guest favourite
Cabin in Panamá
The Crystal House: Luxury Modern Wood Cabin
May 23 – 30
$571 CAD per night
Guest favourite
Home in Costa Esmeralda
Beach House-Amazing Pool, Surf & Pet Friendly
Feb. 23 – Mar. 2
$267 CAD per night

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