
Hotel vacation rentals in Panama Canal
Find and book unique hotels on Airbnb
Top-rated hotels in Panama Canal
Guests agree: these hotels are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama Canal hotels
Family-friendly hotels

3. Apart-Hotel Boutique- Heart of the Old City
Absolutely amazing. Place was spaciouse, clean, well equipped. Location was right in the heart of Caso Viejo and Andres was a true gentlemen our whole stay there. I would highly recommend this place to anyone looking to stay in the heart of Casco Viejo. Dining, entertainment, sight seeing walking all walking distance. truly 5 out of 5 review.

Eco Lodge Garden Room 4, Oceanview Plunge Pool
way better than described. authentic island feel, covered hammock area, literally against the jungle.beautiful

6. Beautiful Boutique Apart-Hotel Views & Services
Wonderful Airbnb in Casco. La Isabella Suites was located in the heart of CV. Apartment was very spacious and comfortable. A balcony overlooked a beautiful park. Great stay. Highly recommended!

2. Boutique Apart-Hotel- Heart Old City
isabella Suites is a lovely apartment, comfortable and very well situated. Andres and all the staff were friendly and very helpful. My family and I really enjoyed our stay at Isabella Suites and the Casco Antiguo of Ciudad de Panama.

Eco Lodge Mango Room 3 Queen Plus
I absolutely LOVED my stay! The area is so beautiful and the room was perfect. Every single person working at the hotel was lovely and so helpful, we had great conversations. The owner even picked me up from the port area. I will definitely be back!

Private Room #4. 3 people
Comfortable place and quite focused for backpackers. The photographs match the place. A good price.

1. Boutique Apart-Hotel - Old Town Center
Andres is an amazing host! He was super responsive, very helpful and was extremely easy to communicate and coordinate with. The apartment was exactly as pictured and the location was very close to all the best restaurants and bars. I would definitely come back and stay here again and recommend it for anyone visiting Casco Viejo in Panama City!
Hotels with a pool

Your second home in Panama.
The truth is that I really liked it, I recommend it and I would return the clean facilities have the option of restaurants nearby, pool, the quiet area at night you can rest well, the only thing that gave the client the option to put if they want or not the daily cleaning in the room, otherwise all excellent.

Jr. Suite Rm #3- Cerro Azul
It was a great visit. I like how pet friendly La Semilla Ecolodge is. I hope the staff also were happy for hosting my mom, my pets, and me. It was a very relaxing experience and we loved the food! - The cook is one of the reasons I always come back :)

Rainforest Suite with Breakfast! 15 min from city
peacefully and beautiful place...

Double Suite-Apartment Hotel Príncipe
Super attention and check-in

Meryland Hotel
After I got moved to room #120, everything improved for the better and I thoroughly enjoyed my stay at the hotel. The staff was VERY accommodating. They were extremely helpful and did whatever they could to assist me. When I come back next year, I would like to stay in the same room #120. 🙏🏾🇵🇦 Víva Panamá! Arriba Colón! #C3

In the heart of the city.
My stay at Hotel Mío in Panama City was wonderful. The place is simply unbeatable - it's incredibly located, right in front of the city's most iconic skyscrapers and buildings, offering a spectacular view. The pool on the rooftop is beautiful and perfect for relaxing. Also, breakfast is included and is delicious. The hotel itself is beautiful, modern and cozy; I would definitely always come back to stay here every time I visit Panama. I want to make a special mention to Josué, from the restaurant area, whose attention was excellent and really made my experience even better. I highly recommend this hotel!

Hotel Room with one full bed
Excellent
Hotels with a patio

Nice hostel, ideal for family trips.
Helped us in need of a place to stay very quick and in national holiday

Kakún Room 12, Cable TV, Refrigerator, Air Conditioning.
Awesome place in a very nice neighbourhood. One of the most spacious rooms I had so far with a private bathroom and a fridge. Shared kitchen has everything you need and grocery stores and restaurants at walking distance. Friendly staff, fast and stable internet. Highly recommended great value for your money.

Eshel Panama Suites, Atlantic suite 04
Great host, beautiful place, great location! Enjoyed the stay!

Hotel Standard Room (2 Double Beds)
excelente lugar super recomendado

cinta costera
Great location and helpful staff

Grand Internationa Hotel - King Room
Excelente, we will return again.
Destinations to explore
- Rentals with outdoor seating Panama Canal
- Hostel rentals Panama Canal
- Rentals with a kayak Panama Canal
- Rentals with lake access Panama Canal
- Rentals with beach access Panama Canal
- Kid-friendly rentals Panama Canal
- Smoking-friendly rentals Panama Canal
- Beachfront rentals Panama Canal
- Rentals with a patio Panama Canal
- House rentals Panama Canal
- Rentals with a hot tub Panama Canal
- Bed and breakfasts Panama Canal
- Rentals with a firepit Panama Canal
- Rentals with pools Panama Canal
- Rentals with a washer and dryer Panama Canal
- Rentals with breakfast Panama Canal
- Apartment rentals Panama Canal
- Rentals with a home theater Panama Canal
- Rentals with an EV charger Panama Canal
- Waterfront rentals Panama Canal
- Rentals with a sauna Panama Canal
- Pet-friendly rentals Panama Canal
- Serviced apartment rentals Panama Canal
- Condo rentals Panama Canal
- Family-friendly rentals Panama Canal
- Rentals with an accessible height bed Panama Canal
- Fitness-friendly rentals Panama Canal
- Hotel rentals Panama
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom