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Hotel vacation rentals in Panama Canal

Find and book unique hotels on Airbnb

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Popular amenities for Panama Canal hotels

Family-friendly hotels

Hotel room in San Felipe
4.9 out of 5 average rating, 40 reviews

3. Apart-Hotel Boutique- Heart of the Old City

TomasRating, 5 stars43 months ago
Absolutely amazing. Place was spaciouse, clean, well equipped. Location was right in the heart of Caso Viejo and Andres was a true gentlemen our whole stay there. I would highly recommend this place to anyone looking to stay in the heart of Casco Viejo. Dining, entertainment, sight seeing walking all walking distance. truly 5 out of 5 review.
Superhost
Private room in Taboga Island
4.69 out of 5 average rating, 51 reviews

Eco Lodge Garden Room 4, Oceanview Plunge Pool

ScottRating, 5 stars3 months ago
way better than described. authentic island feel, covered hammock area, literally against the jungle.beautiful
Hotel room in San Felipe
4.9 out of 5 average rating, 48 reviews

6. Beautiful Boutique Apart-Hotel Views & Services

LeeRating, 5 stars27 months ago
Wonderful Airbnb in Casco. La Isabella Suites was located in the heart of CV. Apartment was very spacious and comfortable. A balcony overlooked a beautiful park. Great stay. Highly recommended!
Hotel room in San Felipe
4.89 out of 5 average rating, 38 reviews

2. Boutique Apart-Hotel- Heart Old City

AndreaRating, 5 stars25 months ago
isabella Suites is a lovely apartment, comfortable and very well situated. Andres and all the staff were friendly and very helpful. My family and I really enjoyed our stay at Isabella Suites and the Casco Antiguo of Ciudad de Panama.
Guest favourite
Private room in Taboga Island
5 out of 5 average rating, 5 reviews

Eco Lodge Mango Room 3 Queen Plus

AudreyRating, 5 stars1 month ago
I absolutely LOVED my stay! The area is so beautiful and the room was perfect. Every single person working at the hotel was lovely and so helpful, we had great conversations. The owner even picked me up from the port area. I will definitely be back!
Private room in Panamá
4.33 out of 5 average rating, 3 reviews

Private Room #4. 3 people

RobertoRating, 5 stars25 months ago
Comfortable place and quite focused for backpackers. The photographs match the place. A good price.
Hotel room in San Felipe
4.95 out of 5 average rating, 43 reviews

1. Boutique Apart-Hotel - Old Town Center

AndrewRating, 5 stars39 months ago
Andres is an amazing host! He was super responsive, very helpful and was extremely easy to communicate and coordinate with. The apartment was exactly as pictured and the location was very close to all the best restaurants and bars. I would definitely come back and stay here again and recommend it for anyone visiting Casco Viejo in Panama City!

Hotels with a pool

Hotel room in Panamá
4.68 out of 5 average rating, 65 reviews

Your second home in Panama.

MarlenRating, 5 stars1 week ago
The truth is that I really liked it, I recommend it and I would return the clean facilities have the option of restaurants nearby, pool, the quiet area at night you can rest well, the only thing that gave the client the option to put if they want or not the daily cleaning in the room, otherwise all excellent.
Hotel room in Panamá
4.25 out of 5 average rating, 4 reviews

Jr. Suite Rm #3- Cerro Azul

CarolinaRating, 5 stars42 months ago
It was a great visit. I like how pet friendly La Semilla Ecolodge is. I hope the staff also were happy for hosting my mom, my pets, and me. It was a very relaxing experience and we loved the food! - The cook is one of the reasons I always come back :)
Hotel room in Panamá
4.44 out of 5 average rating, 18 reviews

Rainforest Suite with Breakfast! 15 min from city

RogelioRating, 5 stars13 months ago
peacefully and beautiful place...
Hotel room in Panamá
4.75 out of 5 average rating, 12 reviews

Double Suite-Apartment Hotel Príncipe

DiegoRating, 5 stars25 months ago
Super attention and check-in
Hotel room in Colón
3.67 out of 5 average rating, 3 reviews

Meryland Hotel

LeahRating, 5 stars11 months ago
After I got moved to room #120, everything improved for the better and I thoroughly enjoyed my stay at the hotel. The staff was VERY accommodating. They were extremely helpful and did whatever they could to assist me. When I come back next year, I would like to stay in the same room #120. 🙏🏾🇵🇦 Víva Panamá! Arriba Colón! #C3
Hotel room in Panamá
New place to stay

In the heart of the city.

CristinaRating, 5 stars1 week ago
My stay at Hotel Mío in Panama City was wonderful. The place is simply unbeatable - it's incredibly located, right in front of the city's most iconic skyscrapers and buildings, offering a spectacular view. The pool on the rooftop is beautiful and perfect for relaxing. Also, breakfast is included and is delicious. The hotel itself is beautiful, modern and cozy; I would definitely always come back to stay here every time I visit Panama. I want to make a special mention to Josué, from the restaurant area, whose attention was excellent and really made my experience even better. I highly recommend this hotel!
Hotel room in Panamá
3.33 out of 5 average rating, 3 reviews

Hotel Room with one full bed

RobertoRating, 5 stars3 months ago
Excellent

Destinations to explore

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