
Family-friendly vacation rentals in Pickens County
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Pickens County
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Pickens County family-friendly rentals
Family-friendly home rentals with a hot tub

Keowee Key Luxury Condo - Stunning Views!

The Rustic Rectangle

Jocassee Gorge Mountain Lodge on creek-Waterfront

Luxury Mountain Getaway

Destination Keowee

5 Mins To Clemson + Hot Tub + Game Room + 5 Kings!

Napaw Mountain Log Cabin~Magical Mt.Top Experience

Spectacular Lakefront Retreat on the Saluda
Family- and pet-friendly home rentals

Comfy, cozy duplex apt in old home downtown Easley

New! Riverfront Tiny Home - Downtown Greenville SC

Secluded Modern A-Frame Cabin w/ Mountain Views

Cozy 3 Br Family Home • 5 min to Clemson Campus

"A Crossvine Cottage

Guest House Eco Cabin

Glamping on the Homestead

Hollytree Cottage at Saluda River Farms
Family-friendly home rentals with a pool

Perfect Tigertown Condo

4br/2ba Great location in heart of Clemson

Sports Basement

Golden T's|Dog Friendly| Walk to Pool|Lake Access

Lakeside Haven on Lake Keowee

123 Game Day Ready

Renfrow's Retreat

Beautiful Lake Keowee Condo with great Amenities
Destinations to explore
- Rentals with breakfast Pickens County
- Pet-friendly rentals Pickens County
- Rentals with a hot tub Pickens County
- Condo rentals Pickens County
- Cabin rentals Pickens County
- Fitness-friendly rentals Pickens County
- Rentals with a washer and dryer Pickens County
- Rentals with pools Pickens County
- Rentals with a kayak Pickens County
- Rentals with a fireplace Pickens County
- Rentals with a patio Pickens County
- RV rentals Pickens County
- House rentals Pickens County
- Waterfront rentals Pickens County
- Rentals with outdoor seating Pickens County
- Apartment rentals Pickens County
- Rentals with lake access Pickens County
- Rentals with a firepit Pickens County
- Private suite rentals Pickens County
- Family-friendly rentals South Carolina
- Family-friendly rentals United States
- Blue Ridge Parkway
- Black Rock Mountain State Park
- River Arts District
- Gorges State Park
- Tugaloo State Park
- Table Rock State Park
- Chimney Rock State Park
- Mountaintop Golf & Lake Club
- Tallulah Gorge State Park
- The North Carolina Arboretum
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Maggie Valley Club
- Biltmore Forest County Club
- Vineyards for Biltmore Winery
- Victoria Valley Vineyards
- Old Edwards Club
- French Broad River Park
- Thomas Wolfe Memorial
- Woolworth Walk
- Discovery Island