
Vacation rentals in Saint Charles
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Top-rated vacation rentals in Saint Charles
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Popular amenities for Saint Charles vacation rentals
Other great vacation rentals in Saint Charles
Guest favourite

Home in St. Louis
5 out of 5 average rating, 5 reviewshome away from home
AshleyRating, 5 stars8 months ago
Took a mini vacay to St Louis with my mom & the kiddos. 3 adults & 2 children had plenty of space for sleeping. The pool & hot tub were so relaxing. It felt so homey. We were offered fresh produce from the garden. Lots of pots & pans if you like to cook while traveling. The bar was nice if you like to relax with a drink. Everyone loved the Pac-Man machine! Tons of at home amenities like streaming channels, coffee maker, potato chips, toys for the kiddos, giant Jenga set, etc. Private & safe location. Only 20-30 mins driving to the heart of St Louis. We really enjoyed our weekend and would recommend this home to anyone needing a family spot to relax.
Guest favourite

Chalet in Innsbrook
4.98 out of 5 average rating, 48 reviewsLuxury, Lakefront Chalet with Hottub and firepits
HannahRating, 5 stars2 months ago
Emily's place was fantastic. She responded right away to questions I had before, during and after our stay. She even forewarned us about the roads leading to the house with the cruddy weather. The house is beautiful, just like the photos. The kitchen is fully stocked and there are plenty of towels for showers and the hot tub. Everything was clean and well cared for. Layout is perfect for larger families and groups of people looking for a quiet place to relax and have fun.
Guest favourite

Home in St. Louis
4.89 out of 5 average rating, 207 reviewsHome away from Home St. Louis Cnty Ladue Schools
RaphaëlleRating, 5 stars3 weeks ago
Lisa was great! I needed a calm, peaceful and clean place for 2 weeks to recover from a surgery and her house was perfect. She was flexible with my arrival and departing time as I got updates from my surgeon and always worked it out with me, even last minute. There's a nice little park and neighborhood around and the house is very comfortable. Highly recommend!
Top guest favourite

Condo in Grafton
4.98 out of 5 average rating, 166 reviewsPelican's Perch
NickRating, 5 stars3 weeks ago
Fantastic host. Beautiful property.
Top guest favourite

Home in Innsbrook
5 out of 5 average rating, 23 reviewsLuxury meets nature @ this Innsbrook stunning home
DeborahRating, 5 stars6 months ago
We picked Charlton’s home for three couples’ annual birthday trip and everything from the start of booking to check-out and in between was perfect. Charlton was a super host and always responsive if we had a question. The home was very clean, super stocked, the furnishings were pleasingly tasteful and the setting was great! Over the years we have traveled to NC, TN, AR and MI for this annual trip and while we always enjoyed our rentals and surroundings, Charlton’s home is the first one that we all said we would go back and stay again! Thanks for a great stay!

Condo in Grafton
4.76 out of 5 average rating, 54 reviewsOne bedroom condo with great riverview.
ColinRating, 5 stars3 days ago
Great place. Great location. Daniel was super nice. Happened to be visiting on a weekend when the flea market was in session! Fun people and watching and fun visiting the flea market. Opposite end of town from the activities of the more active bars, but absolutely walkable and quiet when you wanted to get away from it all.

Cottage in Saint Clair
5 out of 5 average rating, 5 reviewsGuesthouse at Pinemark
BobbyRating, 5 stars6 months ago
Perfect for a wedding in town. Had plenty of room for multiple guests. Would stay here again
Guest favourite

Home in Grafton
4.98 out of 5 average rating, 93 reviewsCozy Cottage off Main Street in Grafton
LeoRating, 5 stars1 month ago
The cottage was perfect for our weekend getaway! Linda was responsive, kind, and helpful. The space was clean and cozy. Highly recommend if you want a cute space close to the fun shops and restaurants in Grafton!
Quick stats about vacation rentals in Saint Charles
Total rentals
200 properties
Total number of reviews
14K reviews
Family-friendly rentals
140 properties are a good fit for families
Pet-friendly rentals
80 properties allow pets
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
130 properties have a dedicated workspace
Destinations to explore
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- House rentals Saint Charles
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- Rentals with a patio Saint Charles
- Rentals with a washer and dryer Saint Charles
- Condo rentals Saint Charles
- Rentals with a firepit Saint Charles
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- Rentals with a fireplace Saint Charles
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- Busch Stadium
- Enterprise Center
- Six Flags St. Louis
- Saint Louis Zoo
- Central West End
- Gateway Arch National Park
- Missouri Botanical Garden
- City Museum
- St. Louis Aquarium at Union Station
- Saint Louis Science Center
- Castlewood State Park
- Hidden Valley Ski Resort
- Missouri History Museum
- Pere Marquette State Park
- Cuivre River State Park
- Cathedral Basilica of Saint Louis
- Adventure Valley Zipline Tours and Paintball Park
- St. Louis Country Club
- The Winery at Aerie's Resort
- Raging Rivers WaterPark
- Grafton Winery the Vineyards
- Boone Valley Golf Club
- Old Warson Country Club
- Bellerive Country Club