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Vacation rentals in Saint Charles

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Top-rated vacation rentals in Saint Charles

Guests agree: these stays are highly rated for location, cleanliness, and more.

Rental unit in Saint Charles
Pop Lucks Guest Suite Steps From Historic Main St
Welcome to Pop Luck's Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite is just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. Pop Luck's is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Also, check out our sister suite The Ella Rose, right next door.
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Rental unit in Saint Charles
Stay on Main!
Stay on Main! Cozy studio apartment directly on Main Street in St. Charles MO. Studio that has a staircase directly to the north end of Main Street, you can be on Main along the shops and restaurants in seconds. Unit has street parking only, and the staircase is shared with another short term rental that I also operate. Free wifi, coffee. There is a full bathroom, kitchen space and a king bed. Unit is brand new, it can be noisy on weekend evenings from the street.
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Rental unit in Saint Charles
South Main Comfort
Check out this very stylish 1 bedroom apartment on South Main. All of the amenities have been checked off the list from a dedicated office space and good sized living room, to an outdoor (shared) dinning area, historic styling in modern comforts. King bed, laundry in unit, dishwasher, and free 24/7 gym access down the street along with off street parking. We've thought of it all to help you be more comfortable for your stay in St. Charles!
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Stay near Saint Charles's top sights

Photo of Ameristar Casino Resort Spa St. Charles
Ameristar Casino Resort Spa St. Charles42 locals recommend
Photo of The Family Arena
The Family Arena12 locals recommend
Photo of Hollywood Casino St. Louis
Hollywood Casino St. Louis20 locals recommend
Photo of St. Charles Convention Center
St. Charles Convention Center6 locals recommend
Photo of Tucanos Brazilian Grill
Tucanos Brazilian Grill8 locals recommend
Photo of Bar Louie - Streets of St. Charles
Bar Louie - Streets of St. Charles21 locals recommend

Other great vacation rentals in Saint Charles

Rental unit in Saint Charles
Lewis and Clark Suite - 1 Bed/1 Bath on Main
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Rental unit in Saint Charles
The Bricks On Main-King Bed on Historic Main St.
Home in Saint Charles
Historic 5th Street House - Fully Rehabbed # 1
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Rental unit in Saint Charles
Ella Rose Guest Suite in Historic Old St Charles
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Rental unit in Saint Charles
2 Bedroom, 1 Bath Apartment, Short Walk to Main!
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Hotel room in Saint Charles
1st Capital Mansion Boutique Hotel - Suite 302
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Rental unit in Saint Charles
2 bedroom apartment with a balcony near Main St!
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Bungalow in Saint Charles
Patio House, secluded in heartbeat of Main Street
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Cottage in Saint Charles
The Rose Cottage -a short walk to Historic Main St
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Home in Saint Charles
Bright & Cozy Shotgun 1 Block from Historic DT.
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Hotel room in Saint Charles
1st Capitol Mansion Boutique Hotel - Suite 301
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Rental unit in Saint Charles
Updated 1 Bedroom Near Main Street St. Charles
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Stays in Saint Charles

Rental unit in Saint Charles
River View - 2 bed, 1 bath on Main Street
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Rental unit in Saint Charles
Quiet 1 bedroom apartment near Main Street!
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Rental unit in Saint Charles
Stylish One Bedroom Apartment close to Main!
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Rental unit in Saint Charles
The Original Custom House!
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Stays in Earth City

Home in Saint Charles
301 Guesthouse/SuperHost/Fast WiFi/Katy Trail/
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Home in Saint Charles
Adorable 2 Bedroom Home
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Private room in Saint Charles
The Teal Room: 1 bedroom in Saint Charles
Private room in Saint Charles
Delightful room close to the St. Louis airport.