
House vacation rentals in Saint Charles
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Top-rated house rentals in Saint Charles
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Saint Charles house rentals
House rentals with a pool

Willow Creek: Mid-Century Oasis

Private indoor pool & sauna

Clark Brick House w/ Pool | Historic St. Charles

Blair's Pool House - Creve Couer Hot Tub Game Room

Arch View Luxury Home:Sauna,Pool,Free Wine &Brkfst

Honeymoon Suite at Camp Skullbone In The Woods

"The Villa" at Villa Augusta in MO wine country

Sunset Mountain Forest Privacy
Weekly house rentals

Charming open 4bd w/ screen-in porch! Sleeps 10!

The Wild Rose Cottage in Historic Old St Charles

Separate Entry Basement Apartment 1BR, 1BA

2bed/2bath Walk Main St Shops Eateries & Bars!

Norma’s House 2

Caper on Kings

*NEW* La Maison Douceur in Historic St Charles

St. Charles Victorian Gem | Steps to Main Street
Private house rentals

Spacious Centrally Located Ranch" Newly Renovated"

Classy + Fun 4bd/1.5bth | Patio Dining | Game Room

10 min airport,12 sleeps, Game Room, Safe Neighbor

#7- The Hub Le Velo Inn 1 bd 1 ba perfect getaway

6.5m to convention center~Fenced~Pets~Long Stays

Fenced St. Charles Charmer

Charming Escape in Grafton!

Honky Tonk Hideaway
Quick stats about house rentals in Saint Charles
Total rentals
110 properties
Total number of reviews
7.5K reviews
Family-friendly rentals
100 properties are a good fit for families
Pet-friendly rentals
50 properties allow pets
Rentals with dedicated workspaces
70 properties have a dedicated workspace
Wifi availability
110 properties include access to wifi
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- Rentals with a fireplace Saint Charles
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- Family-friendly rentals Saint Charles
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- Busch Stadium
- Six Flags St. Louis
- Central West End
- Saint Louis Zoo
- Enterprise Center
- Gateway Arch National Park
- Missouri Botanical Garden
- City Museum
- St. Louis Aquarium at Union Station
- Cuivre River State Park
- Pere Marquette State Park
- The Winery at Aerie's Resort
- Saint Louis Science Center
- Cathedral Basilica of Saint Louis
- Castlewood State Park
- Grafton Winery the Vineyards
- Adventure Valley Zipline Tours and Paintball Park
- St. Louis Country Club
- Missouri History Museum
- Norwood Hills Country Club
- Raging Rivers WaterPark
- Hidden Valley Ski Resort
- Boone Valley Golf Club
- Bellerive Country Club