
Vacation rentals in San Pedro del Espino
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in San Pedro del Espino
Guests agree: these stays are highly rated for location, cleanliness, and more.

Raices de Domingo Cabana
Experience authentic Panama in our family-owned 30-hectare private tropical beachfront paradise. Accessible only by boat (20-min ride from Pixvae or 1hr from Santa Catalina). Gateway to Coiba Island, our remote bay offers pristine jungle, diverse wildlife, and breathtaking views. Enjoy kayaking, fishing, and guided eco-tours. Spot howler monkeys, sloths, and rare birds. Savor fresh tropical fruits and local cuisine. Perfect for nature lovers, photographers, and digital nomads (WiFi available).

Cozy 2 Bedrooms, el Cope/ Retreat at the Mountains
Hermosa cabaña de dos habitaciones y dos baños , den panorámico ubicada a unos 50 minutos de Penonome, Provincia de Cocle, en el Area del Parque Nacional Omar Torrijos Herrera , temperaturas entre 22 y 25 grados C a orillas del turístico Chorro de las Yayas en la comunidad de Barrigon del Cope, distrito de La Pintada. Agradable ambiente rodeado de árboles frutales y hermosas cascadas. Ideal para disfrutar de la naturaleza y relajarse. Cuenta con internet satelital de rápida velocidad .

South Villa w Rooftop Fly- Drive- Coiba day tour
Fly in - charters. Rooftop w/great view! 1000ft2 Your rooftop lounge is perfect for star gazing and birdwatching. Your villa comes with a spacious bedrooms, a fully equipped kitchen (cookware, spices, blender, coffee maker etc), full living area, & your backyard grill. All surrounded by acres of gardens. Fly / drive / take a tour to Coiba Island. If you drive in, we have covered parking for you. If you fly - we have you covered as well! Message for additional information.

Cheerful 3 bedroom countryside Villa with pool.
Forget your worries in this spacious and serene space. This 2 hectares villa includes an 185 square meters house, with 3 air conditioned bedrooms. In addition it includes a swimming pool and 40 square meter ranch. Bedrooms have in total 9 beds, accomodating 12 people. There are 3. 5 bathrooms, internet and hot water. Total perimeter of land is fenced, including an electric gate at the entrance. The price includes the presence of an employee who will support you during your stay.

Country house in Olá, rivers, waterfalls, Los Picachos
Finca La Terapia lives up to its name, nestled in the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day-to-day life of the city. It has 42 private hectares to explore nature. The district of Olá is characterized by having the most beautiful natural landscapes among which we can mention, Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the Finca.

Private Villa with private pool, in Santa Catalina
A beautiful stand-alone 60 sq mt villa, 1 King bed and 1 queen. King size bed in the master bedroom with black out drapes, Queen size bed and fold out couch in the loft area. Full kitchen, living and dining area, flat screen TV, Bathroom with soaps/shampoos, and rainfall showerhead. Large terrace with views as far as the eye can see, with BBQ, dining table and outdoor sectional sofa. Private swimming pool with seating area, pool lounge chairs, lighted gazebo and sun umbrellas.

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Santa Fe villa with a espectacular view
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

d'rosas apartamentos 5PA
Enjoy the simplicity of this quiet and central accommodation.Discover comfort in our cozy home in the heart of Santiago, Veraguas. Just a 5 minute walk from downtown, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring local culture and resting after a day of adventure. We look forward to seeing you!

Mansion in Organic Farm with Heated Pool
Relax with the whole family and friends up to 30 people in this cozy house on an organic farm with animals, crops, tilapia fishing, coffee, rivers, we have a heated pool, a 120-meter covered terrace for you to celebrate your special occasions.

Cabana Vergara Santa Fe
Kick back and relax on this 2 acre ( 1 hectare) private mountain side property, on the Santa Maria River. Equipped with all the amenities you will need to make your stay a home away from home!
Popular amenities for San Pedro del Espino vacation rentals
Other great vacation rentals in San Pedro del Espino

Mountain cabin

Family Hosting

Cozy cabin in El Copé

Mountain cabin, Chepo-Herrera

Lovely place to stay

Country house, La Mismísima

Adulam Cabin

A charming place to enjoy with family or friends
Destinations to explore
- Panama City Vacation rentals
- San José Vacation rentals
- Playa Santa Teresa Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Jaco Vacation rentals
- Uvita Vacation rentals
- Boquete Vacation rentals
- Quepos Vacation rentals
- Playa Blanca Vacation rentals
- Bahía Ballena Vacation rentals
- Limón Vacation rentals
- Ancón Vacation rentals