
Guesthouse vacation rentals in Santa Ana
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouses in Santa Ana
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Santa Ana guesthouses
Family-friendly guesthouses

Orange Slice - Near Disneyland, Chapman Univ.

An LA Escapade.

Cozy city hideaway for families.

Guest House in Huntington Beach (400 sq ft)

1919 Spanish Casita | 12 min. to Anaheim

Disney Guesthouse Sleeps 7 near the Beaches in O.C

Adorable little guest house with beautiful garden

Hidden Modern Getaway
Guesthouses with a patio

Luxury Cottage Near Old Town, Rosebowl, and More

Adorable Back House w/Secluded Garden & Yard

Private Spanish Guesthouse w/ Pool & Views

Adorable 1 bedroom house with pool and patio

Modern Hillside Escape surrounded by Nature

Champagne Retreat in Upland

Stylish Atwater Village Guest Suite w/Private Yard

motel-like studio w/ private bath & kitchenette
Guesthouse rentals with a washer and dryer

Private & Very Clean just 15 minutes to Disneyland

The Silver Lake Guesthouse

Villa del Sol in La Verne, CA Private Home

Charming 2 br condo nr. beach

Urban Retreat

Light+bright 1 br guest house w/modern rustic vibe

Studio Back House w/ Kitchenette and Washer/Dryer

Modern Cottage Central to Disney, Universal & DTLA
Quick stats about guesthouse rentals in Santa Ana
Total rentals
80 properties
Nightly prices starting at
$83 CAD before taxes and fees
Total number of reviews
6.6K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
30 properties have a dedicated workspace
Destinations to explore
- Southern California Vacation rentals
- Los Angeles Vacation rentals
- Stanton Vacation rentals
- Las Vegas Vacation rentals
- Channel Islands of California Vacation rentals
- San Diego Vacation rentals
- Central California Vacation rentals
- Palm Springs Vacation rentals
- San Fernando Valley Vacation rentals
- Henderson Vacation rentals
- Las Vegas Strip Vacation rentals
- Anaheim Vacation rentals
- Rentals with a hot tub Santa Ana
- Rentals with breakfast Santa Ana
- Rentals with beach access Santa Ana
- Family-friendly rentals Santa Ana
- Fitness-friendly rentals Santa Ana
- Hotel rentals Santa Ana
- Rentals with outdoor seating Santa Ana
- Rentals with a fireplace Santa Ana
- Condo rentals Santa Ana
- Rentals with a firepit Santa Ana
- Rentals with pools Santa Ana
- Cottage rentals Santa Ana
- Pet-friendly rentals Santa Ana
- Rentals with an EV charger Santa Ana
- Villa rentals Santa Ana
- Apartment rentals Santa Ana
- Rentals with a patio Santa Ana
- Townhouse rentals Santa Ana
- Rentals with an accessible height toilet Santa Ana
- Smoking-friendly rentals Santa Ana
- Rentals with a washer and dryer Santa Ana
- Rentals with an accessible height bed Santa Ana
- House rentals Santa Ana
- Private suite rentals Santa Ana
- Guesthouse rentals Orange County
- Guesthouse rentals California
- Guesthouse rentals United States
- Venice Beach
- Santa Catalina Island
- Santa Monica Beach
- Disneyland Park
- Oceanside City Beach
- Los Angeles Convention Center
- Crypto.com Arena
- Hollywood Walk of Fame
- Universal Studios Hollywood
- Santa Monica State Beach
- SoFi Stadium
- University of Southern California
- University of California, Los Angeles
- Rose Bowl Stadium
- San Clemente State Beach
- Knott’S Berry Farm
- Huntington Beach, California
- Bolsa Chica State Beach
- San Onofre Beach
- The Forum
- Oceanside Harbor
- Topanga Beach
- Disney California Adventure Park
- Pechanga Resort Casino