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Vacation rentals in Santa Cruz

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
An infinity pool reflects the city skyline, featuring sleek high-rise buildings in the background. The pool's calm waters create a serene environment, while green foliage frames the area, enhancing the visual appeal of this outdoor space.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

Film view, spacious, tub, balcony and garage

Upon entering, you appreciate the elegance and style of decoration, high ceilings that provide a feeling of spaciousness and luminosity. The living room is spacious and comfortable, with a luxury built-in kitchen that adds a touch of warmth and elegance. Social areas to impress, with designer and high quality furniture. Churrasquera and a wonderful infinity pool. But what really stands out about this apartment is the breathtaking view that is enjoyed from the terrace or the balcony.

Guest favourite
A modern condominium building is situated at the corner of a quiet street, featuring multiple floors with large balconies. Green landscaping surrounds the property, and a clear blue sky provides a bright backdrop, highlighting the building’s contemporary architecture.
Loft in Santa Cruz de la Sierra
4.91 out of 5 average rating, 178 reviews

Modern Studio Apartment near Zoo - Fast WiFi

Bienvenido a tu hogar en Santa Cruz! Disfrutá un monoambiente moderno, seguro y totalmente equipado, a pasos del Zoológico. Ideal para parejas, ejecutivos o nómadas digitales. Ofrecemos Internet de alta velocidad, estación de trabajo, cocina equipada y atención personalizada para una estadía inolvidable. Ubicación estratégica en zona tranquila, con self check-in y WiFi rápido. Totalmente equipado y perfecto para largas estadías, garantizando tu confort y seguridad. Te esperamos!

Top guest favourite
Green Tower, one of the tallest buildings in Bolivia, showcases modern architecture with its glass facade reflecting the surrounding cityscape. The image captures the building's contemporary design, set against a backdrop of Santa Cruz, featuring both urban and natural elements.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 25 reviews

Green Tower - 26th Floor Spectacular Views

Enjoy your stay in the highest airbnb in Santa Cruz, and in the best building in the city, in the facilities you can enjoy Pool, Steam Sauna, spectacular views from the 26th floor to the beautiful Manzana 40 building, the nature of the ecological cord and the urubo. A few steps from the supermarket, restaurants, mall, business centre, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Top guest favourite
A modern interior is presented, featuring a cozy seating area with a dark sofa, complemented by a circular coffee table. A wooden divider offers separation from the sleeping area, where a spacious bed with neutral bedding is visible. Natural light fills the space from the nearby window.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 24 reviews

SkyLuxia Depto nou Equipetrol - Seguro&Lujoso

Enjoy and relax in this space for two people, new, quiet and elegant. Located in Equipetrol, the best area of Santa Cruz, close to restaurants, bars and shopping malls. It offers luxury, comfort, comfort, and safety. Everything to enjoy Santa Cruz. WiFi, Smart TV, Cable TV, AC and washing machine. ✔ Extensive Swimming Pool ✔ Equipped gym ✔ Sauna and Relaxation Areas Business ✔ room and coworking ✔ 27/7 Security Live the best experience in Equipetrol. 🌟

Top guest favourite
A modern living area features a comfortable sofa adorned with decorative pillows, alongside a sleek TV unit. Large windows offer panoramic city views, while two round mirrors enhance the brightness of the space. A small chair and indoor plant add a touch of decor.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 42 reviews

Modern Apt WiFi, AC, Kitchen, Pool, Washer, Parkng

✨ A space designed for your comfort and relaxation. Located in a safe and quiet area, this modern apartment combines style, convenience, and technology to offer you a unique experience. Perfect for business travelers, couples, or small families, this accommodation features high-speed WiFi, air conditioning, and premium entertainment, along with access to a pool, gym, and free parking. 📌 Enjoy an unforgettable stay with all the amenities you deserve!

Top guest favourite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 34 reviews

Elegante departamento familiar en Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

Top guest favourite
A cozy sleeping area features a spacious bed adorned with patterned bedding and two decorative pillows. A vibrant painting depicting a colorful street scene hangs above the headboard, complemented by wooden wall panels and a small shelf displaying decor.
Loft in Santa Cruz de la Sierra
4.94 out of 5 average rating, 197 reviews

Equipetrol: Luxury studio superking bed & Restobar

Magnificent apartment located in a privileged area of ​​the city, furnished and equipped with the essentials for a pleasant stay. The studio has a super king size bed, living-dining room, large kitchen, closet, balcony with unbeatable view of the city and private bathroom. Access to swimming pool, Resto-Bar, co-work room, entertainment room, pool table, barbecue and outdoor environments with a beautiful view of Equipetrol all on the 7th floor.

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Condo in Santa Cruz de la Sierra
4.88 out of 5 average rating, 224 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 108 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Apartment in Santa Cruz de la Sierra
4.9 out of 5 average rating, 105 reviews

Hermoso Apartamento 1 dormitorio Equipe

One-bedroom apartment, perfect for your next stay in Santa Cruz de la Sierra! Centrally located a few steps from Equipetrol, the city's commercial, business and social center. The unit has a cozy space that offers all the necessary amenities for a comfortable and memorable stay. It includes a service area, washer and dryer, iron, coffee maker, dishes, bed linens, 2 55” smart TVs with cable, Netflix, and a sofa bed. Reserve now!

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Apartment in Santa Cruz de la Sierra
4.87 out of 5 average rating, 123 reviews

Comfortable and modern monoenvironment - beautiful view

Bienvenidos a la zona más activa de Santa Cruz! El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi y tv cable con canales nacionales y extranjeros y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

Top guest favourite
A large rooftop pool is framed by vibrant greenery, reflecting the clear blue sky and surrounding skyline. Modern buildings can be seen in the distance, providing a sense of the urban environment while inviting relaxation and leisure.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 18 reviews

Modern Studio | Prime Location

Modern and comfortable studio in the heart of Equipetrol, steps from top cafes, restaurants, and a major shopping mall. The building offers a large pool, fully equipped gym, steam and dry sauna, and a game room with pool and foosball tables. Ideal for business or leisure stays in a vibrant and secure area of Santa Cruz.

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Bolivia
  3. Santa Cruz