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Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

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Top guest favourite
A charming garden area is framed by an archway covered in greenery, with colorful lights strung overhead. A white picket fence borders a pathway leading deeper into the garden, while vibrant decor is visible in the background.
Loft in Mexico City
4.94 out of 5 average rating, 135 reviews

Casa Jacarandas: boutique loft with private patio

Este encantador loft con increíble estilo se ubica dentro de una casona de principios del siglo XX. Única en la zona Escandon, con excelente ubicación y extraordinaria cercanía a la Colonia Condesa, Roma, Napoles, y zona centro de la CDMX. Aquí tendrás un espacio que cuenta con una sala, comedor, cocineta, tv, wifi, baño privado y un mezzanine con cama queen. También contarás con un jardín privado bajo la sombra de un hermoso árbol de jacarandas. Tenemos dos amigables perros en el jardín común.

Guest favourite
A sunlit living area features a mix of comfortable seating, with two wicker chairs and a wooden sofa. A glass coffee table sits at the center, surrounded by large windows offering views of the garden. Lush vegetation and flowering plants are visible outside.
Cabin in Mexico City
4.9 out of 5 average rating, 29 reviews

Cabin with garden and kitchen near chinampas

Escape to a 1,080 ft² cabin retreat nestled in Xochimilco’s UNESCO-protected chinampa zone. Bask in serenity with a 4,310 ft² private garden, inside free parking, and optional lake access. Inside, free parking, plush linens, a fan, complimentary tea, high-speed Wi-Fi, etc., await you—while modern security cameras ensure peace of mind. Stroll one minute to the Olympic track or lagoon, and 20 minutes to Xochimilco Centro. Unplug under a canopy of stars in this elegant, eco-friendly sanctuary.

Top guest favourite
A cozy bedroom features a single bed adorned with a striped blanket and decorative fringe. A small wooden desk and chair are positioned against the wall. Shelves display towels and toiletries. Light wood flooring complements the simple, colorful wall accents.
Guest suite in San Diego Churubusco
4.93 out of 5 average rating, 257 reviews

Coyoacán, Independent room with stove & bath

You will love my space because it is an independent Mexican style room with private bathroom and small space for cooking, table to work or eat. Fully remodeled, high quality mattress and wifi. Space safe, nice, bright and comfortable for one person. The room has its own entrance. Guest is given keys to the room and to the house entrance. Places of interest: Frida Kahlo Museum, Coyoacán, plus a direct walking through subway station direct to downtown. Perfect location for walking in City.

Guest favourite
The image captures a spacious terrace adorned with various potted plants, leading to a bright bedroom area. Large glass doors open to the patio, allowing natural light to fill the space. A serene landscape and a clear blue sky complement the vibrant greenery.
Loft in Santa María la Ribera
4.96 out of 5 average rating, 307 reviews

Sunny loft with a big terrace in a historic area

New and spacious two stories loft on an award winning renovated building from the 1940´s. Security 24/7 , personal digital code to access the apartment, wifi, fully equipped kitchen, Smart TV with Netflix/Mubi, and a shared laundry room in the building. The loft has one patio in the first floor and a huge terrace full of plants on the second floor next to the bedroom. It is usually very quite but there could be a little noise during the day if another apartment is doing renovations.

Top guest favourite
A minimalist sleeping area features a single bed dressed with a light-colored duvet and a yellow accent pillow. A small desk and chair are positioned nearby, complemented by a shelf with storage options. A framed artwork adds a touch of color to the wall, illuminated by soft lighting.
Loft in Moctezuma
4.97 out of 5 average rating, 406 reviews

Miniloft 10: CDMX Airport, GNP Stadium, TAPO.

Enjoy this practical and comfortable loft 10 minutes from Mexico City Airport, GNP/Autodromo Stadium, Palacio de los Deportes, TAPO Bus Terminal, Oceania/IkEA Shopping Center with cafes, bars, restaurants, cinemas, and shops. The loft is located on the second level, with a single bed, equipped kitchen, ROKU TV, desk, safe, Wi-Fi, and a private bathroom. The building has a shared washing machine and roof garden. There is a park in front of the building.

Guest favourite
An open-plan living area features a dining table with black chairs and a contrasting wooden surface. Natural light floods the space through large windows, illuminating a relaxed seating area and green plants. Decorative wall pieces add character to the minimalist design.
Loft in Barrio Santa Catarina
4.9 out of 5 average rating, 187 reviews

Casa Mavi's loft in Coyoacán

Welcome to Coyoacán! Great loft of 120 m2 located just 5 minutes walk from the center of Coyoacán. Live the experience of this quiet and bright open space, ideal for rest or work and decorated with objects full of stories. The loft is located on the third floor of Casa Mavi, a former factory that was remodeled to create a charming place that makes it unique. It has terraces for common use. With option for a third guest. Wifi 200 megabytes.

Guest favourite
A multi-story building is surrounded by lush greenery and vibrant flowering plants. Large windows are visible on the façade, allowing natural light to filter in. The driveway is paved, and a car is parked in the designated area, showcasing the accessibility of the property.
Condo in Ampliación Tepepan
4.9 out of 5 average rating, 97 reviews

Apartment in Tepepan

The accommodation is an apartment separate from the main house, with its own access. It has a bedroom (2 people, double bed); 1 studio (with breakfast bar, desk, chairs and bookcases); kitchenette (without stove, only with an electric burner); full bathroom; and 1 parking space. Located in the south of Mexico City, 5 minutes from the Dolores Olmedo Museum and the Noria Light Rail, 10 minutes from the famous trajineras and the flower market.

Guest favourite
A modern studio features a spacious bed framed by large windows, offering views of the cityscape. Two comfortable armchairs with a small table are positioned nearby, with soft natural light enhancing the neutral tones of the decor.
Loft in Juárez
4.95 out of 5 average rating, 107 reviews

TOP Views! Amazing loft in the heart of Reforma

Despierta en el corazón de la ciudad con vistas que te roban el aliento. Este loft moderno y elegante te sitúa sobre Reforma, justo frente al Monumento a la Revolución. Ideal para parejas, viajeros de negocios o nómadas digitales, el espacio combina confort, diseño y una ubicación inmejorable. Disfruta de amenidades como alberca, gimnasio, vigilancia 24/7 y acceso rápido a los principales puntos turísticos y gastronómicos de CDMX.

Guest favourite
A living area features a navy blue sofa adorned with decorative pillows, positioned next to a comfortable bed. A round dining table is set with plates, utensils, and glasses, complemented by a small potted plant and placemat. Soft natural light filters through large windows.
Condo in Periodistas
5 out of 5 average rating, 30 reviews

New apartment with a forest view!

Enjoy a brand new apartment equipped with an unparalleled forest view and amenities such as a swimming pool, gym, cinema, game room, garden, parking, reception, and 24-hour security. Strategically located next to a supermarket and shopping mall. Very close to Polanco, Citibanamex exhibition center, National Auditorium, new United States embassy and 10 minutes from the most attractive tourist and business areas of Mexico City.

Superhost
A spacious sleeping area features a large bed with light-colored bedding, complemented by a decorative coverlet displaying Parisian themes. The minimalist decor includes bedside shelves and a large headboard, enhancing the room's modern design and functionality.
Apartment in Mexico City
4.89 out of 5 average rating, 94 reviews

B Apartment, bathroom, minibar, garden and barbecue.

New apartment with a parking space, 10 blocks or 5 minutes from Terminal line 12 of the Tlahuac Metro, with a full bathroom, microwave oven, minibar, and sharing a large 500m garden with a wood and charcoal grill, and a gas grill in functional facilities for work and rest. Located on the first floor, it has a terrace where you can rest or simply sunbathe.

Guest favourite
Tiny homes in Jardines del Pedregal de San Ángel
5 out of 5 average rating, 9 reviews

A little house in the garden. Next to CU

In the corner of a beautiful garden, this little house opens its doors for you to rest and feel comfortable, rest and listen to the birds at dawn. It has a bedroom, a bathroom and a small kitchen for your comfort. Although it shares the entrance with the residence to which it belongs, the space is independent and memorable.

Guest favourite
An outdoor terrace is presented with a wooden pergola, casting dynamic shadows across a spacious wooden dining table surrounded by benches. A kitchen area is visible with a modern design, and various potted plants are arranged along the perimeter, enhancing the natural ambiance.
Loft in Barrio Santa Catarina
4.94 out of 5 average rating, 600 reviews

ECO-ROOF with terrace in the heart of Coyoacán

Nice and cozy room with a private balcony in the heart of Coyoacán, one of the most picturesque and traditional neighborhoods in Mexico City. Located a 5-minute walk from downtown Coyoacan, traditional restaurants, cafes, craft bazaars, and museums.

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
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