Hotels in St. Charles County

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Top-rated hotels in St. Charles County

Guests agree: these hotels are highly rated for location, cleanliness, and more.

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A spacious bedroom features a large bed with crisp white linens and a textured accent wall in deep blue. A flat-screen television is mounted on the wall, and a desk with a chair is positioned nearby. Natural light enters through a window adorned with simple curtains.

Hotel room in St. Louis

4.74 out of 5 average rating, 166 reviews

The West End by Cortex, Forest Park, BJC & Zoo

Welcome to The West End, your ideal retreat in the heart of the Central West End! Just steps away from charming attractions like forest park. Great amenities are: - Fast and stable fiber internet connection - Communal kitchen with 2 sets of range, ovens, fridges, microwaves, and dishwashers. - Complimentary coffee - Secured Gated Parking $10/Night - Hot Tub - Great patio space with seating and a gas grill - Complimentary Netflix, Hulu, Disney+, and ESPN+, where available and local TV channel

Hotel room in St. Louis

4.95 out of 5 average rating, 22 reviews

Near Central West End | Free Breakfast + Pool. Bar

Stay smart, stylish, and sustainable in the heart of St. Louis Midtown. Just steps from Forest Park, SLU, and the Grand Center Arts District, Element St. Louis Midtown features sleek, apartment-style suites with full kitchens and eco-conscious touches. Unwind in the indoor pool, sip cocktails at the on-site bar, and start your day with free hot breakfast. With EV charging, a fitness center, and walkable hotspots nearby, this stay blends comfort, convenience, and a touch of luxury.

The exterior of the AC Hotel Central West End is displayed, featuring a modern six-story building with brick cladding and large windows. The entryway is accented with wooden slats, and a welcoming glass facade reflects the evening sky.

Hotel room in St. Louis

4.75 out of 5 average rating, 52 reviews

Walk to Forest Park + On-site Restaurant & Bar

Stay steps from Forest Park and the best of Central West End at AC Hotel St. Louis. With sleek European-inspired design, a vibrant lobby bar, and walkable access to top restaurants, museums, and nightlife, you’re perfectly placed for STL adventures. Grab a crafted cocktail, hit the 24/7 gym, or explore iconic spots like the Zoo and Art Museum—all just minutes away. Whether you're here for business, culture, or Cardinals baseball, this stay keeps you close to it all.

A spacious living area featuring a comfortable sofa and a coffee table. A desk with an ergonomic chair is positioned nearby, and a dresser is visible next to the 43-inch television. Natural light filters through the window treatments, illuminating the overall layout.

Hotel room in St. Louis

5 out of 5 average rating, 4 reviews

Downtown Studio l Swimming. Gym. Free Breakfast.

Welcome to Residence Inn by Marriott St. Louis Downtown, nestled in Missouri! We provide a great location in downtown St. Louis, spacious lodgings, and great facilities such as a pool and fitness center. Enjoy a daily breakfast buffet - on us! Then, head out to one of the nearby attractions, such as The Gateway Arch and St. Louis Zoo. ✔ Pool ✔ Fitness center ✔ Free breakfast ✔ Pet-friendly ✔ Indoor and outdoor fireplaces ✔ Mini-market ✔ Downtown location

Hotel room in Valley Park

4.75 out of 5 average rating, 20 reviews

Near Downtown St. Louis + Breakfast. Pool. Gym.

Located off I-44, Spark by Hilton St. Louis Southwest offers the perfect launchpad for family fun. Ride the coasters at Six Flags St. Louis just 15 minutes away, or take a short drive to the Gateway Arch and St. Louis Zoo. Start your morning with a free hot breakfast, then unwind in our seasonal outdoor pool or 24-hour fitness center. With free WiFi, pet-friendly rooms, and easy access to Lone Elk Park, we provide a comfortable, convenient stay in Valley Park.

The Royal Sonesta Chase Park Plaza St. Louis

5 out of 5 average rating, 5 reviews

The Royal Sonesta Chase Park Plaza St. Louis

This newly renovated room is accessed via private keyed elevator and features refined decor, custom hardwood finishes, and fine furnishings, including one king bed and work desk with chair. Amenities include marble bathroom, robes, mini-fridge, Keurig coffee maker, iron/ironing board, complimentary wifi, lighted make-up mirror, spa-quality toiletries, and flat-screen television with Google Chromecast and premium movie channels.

Hotel room in St. Louis

4.85 out of 5 average rating, 20 reviews

Lafayette House | Boutique Hotel | Fleur De Lys

Maison Lafayette Boutique Hotel is a restored historic mansion in the heart of Lafayette Square, one of St. Louis’s most iconic neighborhoods. Formerly a traditional bed and breakfast, the property now offers private guest rooms with ensuite bathrooms, elegant shared spaces, and curated amenities. Guests enjoy a refined, quiet stay minutes from downtown, Lafayette Park, dining, and major attractions.

An indoor pool area features a clear blue water pool surrounded by light-colored tiles. Several metal chairs and tables are positioned near the pool, along with potted plants that add a touch of greenery. A lounge area with vibrant red seating is visible in the background.

Hotel room in Berkeley

4.5 out of 5 average rating, 8 reviews

Stay Near Airport | Free Shuttle. Pools. Dining

Make your St. Louis trip effortless and luxurious at Renaissance St. Louis Airport Hotel, just one mile from Lambert International Airport — with a complimentary airport shuttle to get you there fast. Take a dip in the indoor or outdoor pool, stay active in the fully equipped gym, or savor a meal at our on-site restaurant and bar. Your St. Louis stay starts with ease and ends with pure relaxation.

Guest favourite

Hotel room in Saint Charles

4.95 out of 5 average rating, 21 reviews

Downtown Boutique Comfort w/ Style- Otter Suite

The Otter Suite at the Divine Otter Hotel offers a stylish 2-bedroom escape, sleeping up to 6 guests. Enjoy upscale furnishings, a modern design, and a spacious full bathroom with plenty of natural light. Located in the heart of Historic Main Street Saint Charles, you’ll be steps away from shops, dining, and more. This impressive suite is the perfect blend of comfort and location!

Top guest favourite

The exterior of a historic Victorian house is presented, featuring a light-colored facade with decorative motifs around the windows. Lush greenery frames the entrance, with manicured hedges leading to the front steps. The building showcases multiple stories and distinctive architectural details.

Hotel room in St. Louis

4.98 out of 5 average rating, 96 reviews

Lafayette Square Inn - Lafayette Room

Lafayette square has the largest collection of renovated victorian houses in America and this is one of them. Dating to 1876, this historic home offers quality amenities. We are located near: America's Center Convention Complex - 2 Miles Bush stadium - 1.5 Miles Stifel Theatre - 1.4 miles Gateway Arch - 2.1 Mi Enterprise Center - 1.2 Mi Delmar Hall - 7 Mi

Hotel room in Clayton

4.83 out of 5 average rating, 18 reviews

Less than 2 miles from St. Louis Galleria Mall

Find us a mile from I-170 and less than two miles from St. Louis Galleria Mall and Washington University in St. Louis. St. Louis Zoo and Forest Park are a 10-minute drive away, while The Pageant on Delmar Loop is a 6-minute drive from our door. Enjoy daily free hot breakfast served daily, a drink at Danielle's Bar, free WiFi, and our indoor mineral pool.

Hotel room in St. Louis

5 out of 5 average rating, 3 reviews

King| LaQuinta St. Louis Route 66| Near Six Flags

Located just off historic Route 66, La Quinta Inn & Suites St. Louis Route 66 offers easy access to Six Flags St. Louis and downtown attractions. This king room provides a comfortable stay with a plush bed and work area, ideal for both leisure and business travelers. Relax after a day of exploring St. Louis with all the modern conveniences you need.