Hotel vacation rentals in St. Charles County

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Top-rated hotels in St. Charles County

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Hotel room in St. Louis

4.6 out of 5 average rating, 10 reviews

The West End by Cortex, Forest Park, BJC & Zoo

Welcome to The West End, your ideal retreat in the heart of the Central West End! Just steps away from charming attractions like forest park. Great amenities are: - Fast and stable fiber internet connection - Communal kitchen with 2 sets of range, ovens, fridges, microwaves, and dishwashers. - Complimentary coffee - Secured Gated Parking $10/Night - Hot Tub - Great patio space with seating and a gas grill - Complimentary Netflix, Hulu, Disney+, and ESPN+, where available and local TV channel

Guest favourite

Hotel room in St. Louis

4.93 out of 5 average rating, 116 reviews

Ultramodern 2BR Corner Loft w/Designer Features

The Nash Loft is a stunning corner loft with two bedrooms + two designer bathrooms with black stainless fixtures and frameless glass showers, 12’ ceilings, an Edison-lit community courtyard, stackable washer + dryer, a fully-equipped kitchen with black stainless appliances, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Guest favourite

Hotel room in St. Louis

5 out of 5 average rating, 21 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

Experience timeless elegance in The Hill Suite, where Gothic architectural details blend with modern luxury. Framed by original stained glass windows, this retreat features rich wood finishes and soaring ceilings. Unwind in your plush queen bed or cozy up by the ambient electric fireplace. The spa-like en-suite bathroom offers heated floors, designer tilework, and a deep soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

Top guest favourite

Hotel room in Saint Charles

5 out of 5 average rating, 14 reviews

#2 Swiftwalker Parade LeVelo Inn

Make some memories at this unique and family-friendly place.Under the copper eyebrow on the front of the building, this door will lead you down a hallway that will take you to an original staircase of this historic building. Lots of natural light as well as an exterior door that exits out to a parade balcony to check out life on N 2nd Street. king-size bed, living area with large sectional couch for a comfortable stay extra guests with an extra thick queen mattress. Private kitchen/dining.

Hotel room in Alton

4.95 out of 5 average rating, 39 reviews

Three Bedroom River View Guest House-3 Bathrooms

An escape from the ordinary in our River view guest house. On bottom level is an art glass shop offering classes in stained , fused, and mosaic art glass you may partake in at an additional cost. Bicycle built for two available for cycling the national scenic byway. Walk to shops, casino, restaurants, breweries, and concerts. Cruise ship dock is 1/2 mile away. Extend your stay before or after to enjoy taking a stained glass class offered in our shop below as a souvenir of your trip.

Hotel room in Earth City

4.86 out of 5 average rating, 7 reviews

Perfect Getaway Near The Airport | Free Breakfast

The Holiday Inn St. Louis Airport West Earth City is just 6 miles from the St. Louis-Lambert International Airport and offers a complimentary airport shuttle. Conveniently located near downtown St. Louis and Historic St. Charles, travelers and guests will be in an ideal location for shopping, dining, and entertainment. Visitors can dine or enjoy cocktails at Elements, our on-site restaurant and bar. A well-equipped fitness center and a relaxing heated indoor pool complete your stay.

Hotel room in St. Louis

4.93 out of 5 average rating, 14 reviews

Huge Penthouse Suite for Fun Group Stay

The Penthouse Suite is ideal for a large group stay! This sprawling 2,000 Sqft open studio style layout sleeps 6-20+ Guests. Featuring 1 private bedroom offering a King-size bed, 6 Queen bunks, 2 reg Queens, 2 Full, & 2 Twins. A full kitchen and a bathroom w/ a shower. Located on the top (3rd) floor, providing great sunset & city views. Guests have shared access to an expansive and eclectic GameRoom with another full kitchen, bathroom, TVs, pool table, ping pong, and darts.

Hotel room in Saint Charles

4.77 out of 5 average rating, 214 reviews

1st Capitol Mansion Boutique Hotel - Suite 201

This unit is a hotel style unit that is located in the heart of downtown historic St. Charles. It's located right across the street from a coffee shop, wine bar and the oldest local pub in St. Charles. It is just a few blocks away from all of the shopping and restaurants on Main St. The mansion was built in 1902 and still holds all of the charm from back then. This is a private suite with it's entrance from the rear of the building right off the parking lot.

Hotel room in St. Louis

4.77 out of 5 average rating, 13 reviews

Downtown Suite l Swim. Gym. Free Breakfast.

Welcome to Residence Inn by Marriott St. Louis Downtown, nestled in Missouri! We provide a great location in downtown St. Louis, spacious lodgings, and great facilities such as a pool and fitness center. Enjoy a daily breakfast buffet - on us! Then, head out to one of the nearby attractions, such as The Gateway Arch and St. Louis Zoo. ✔ Pool ✔ Fitness center ✔ Free breakfast ✔ Pet-friendly ✔ Indoor and outdoor fireplaces ✔ Mini-market ✔ Downtown location

Superhost

Hotel room in Berkeley

4.46 out of 5 average rating, 13 reviews

Luxury Stay Near Airport | 2 Pools, Free Shuttle

Experience luxury at Renaissance St. Louis Airport Hotel, just a mile from St. Louis Lambert International Airport with a free airport shuttle. Relax at our indoor and outdoor pools, or stay fit in our gym. Ideal for leisure, with nearby access to Enterprise Center, Delmar Loop, and top attractions like Missouri Botanical Gardens & Gateway Arch Riverfront. Perfect for travelers seeking comfort and convenience.

Private room in Ferguson

5 out of 5 average rating, 4 reviews

Haunted 1905 Victorian home

We offer a unique opportunity to sleep in a 100 year old haunted house. There are two known spirits that have been heard and seen on the premises. The bedroom is a simple affair on the third floor, but the center of paranormal activity. For an additional fee, guests can participate in casting a spell of their choice or receive a tarot reading in an authentic witch apothecary.