Vacation rentals in Wapello

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Top-rated vacation rentals in Wapello

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Guest favourite
A historic four-bedroom home is captured with tall trees framing the exterior, set against a clear blue sky. The architectural features include a prominent turret and multiple windows, reflecting the home's charm. A snow-dusted yard leads to a view of the nearby Mississippi River.
Home in Muscatine
4.96 out of 5 average rating, 135 reviews

Historic West Hill Retreat

Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Guest favourite
A wooden deck overlooks Lake Odessa, with several blue chairs arranged for seating. The calm water reflects the cloudy sky, and green vegetation borders the shore, creating a peaceful lakeside environment.
Cabin in Wapello
4.89 out of 5 average rating, 18 reviews

Waterfront Cabin on Lake Odessa

Take it easy at this unique and tranquil getaway on Lake Odessa in Wapello, Iowa. Enjoy beautiful views and access to fishing, boating, and other natural attractions. This quaint cabin offers plenty of space to relax and enjoy the peace and quiet. Cabin offers two bedrooms with 3 beds and 1 sleeper sofa in the living room. Enjoy two full bathrooms, a half bath and a full kitchen. Cabin is within walking distance of water access, boat ramp, fishing areas and a cute local seasonal restaurant.

Guest favourite
A spacious home is visible with a combination of brick and siding exterior, featuring multiple gables and a large covered porch. A manicured lawn extends toward a serene pond, enhancing the natural surroundings. Clear blue skies contribute to the relaxing outdoor atmosphere.
Home in Morning Sun
4.91 out of 5 average rating, 242 reviews

Buckman's Guesthouse BnB (5 Bedrooms+)

Enjoy the comfort and welcoming atmosphere of a home built to entertain family & friends. There are 5 guest bedrooms rooms: Room 1-King bed, sofa bed & recliner Room 2-Queen & sofa bed Room 3-Twin beds & convertible sofa Room 4-Queen & sofa bed Room 5-King & recliner Rooms 1,2 &5 have in suite bathrooms. Bathroom for room 4 is next door. Rooms 2 &3 share an inner door; ideal for parents with children. Breakfast is included. To book a room instead of the house, see separate listings.

Guest favourite
The exterior of a charming farmhouse is presented, featuring a white facade with a sloped roof. Lush green grass surrounds the front porch, which is shaded by large trees. A welcoming atmosphere is suggested by the open door and inviting entryway.
Home in Muscatine
4.97 out of 5 average rating, 113 reviews

Michelle's Place- The Farm House

Welcome to Michelle's Place- The Farm House. Where it's a farm feel, centrally located in town. It's a completely remodeled home with intentional planning and beautiful design for you to come rest at a home away from home. Close to parks, and walking trials while also only 4 minutes away from the historic downtown area! All aspects inside the home were uniquely picked by the host. With seasonal farm fresh varieties of berries, fruits, and vegetables to be enjoyed in your backyard!

Guest favourite
A view of the cabin's exterior showcases a spacious deck surrounded by lush greenery. The building features a gray color with large windows, enhancing natural light. A picnic table is positioned on the deck, offering a place to enjoy meals with scenic lake views.
Cabin in Wapello
4.93 out of 5 average rating, 15 reviews

Iowa Cabin:Rustic+Cozy. Lake Odessa Iowa Waterview

Lake Odessa is a hidden Iowa gem, perfect for those looking to escape into nature. It’s a great spot for outdoor enthusiasts who love duck hunting, fishing, kayaking, birdwatching & hiking. The lake hosts a variety of wildlife, bald eagles, herons, and migrating waterfowl. From the deck enjoy sunrise views over the water, quiet evenings by the fire, and the soothing sounds of nature all around. Our recently updated cabin is the perfect getaway from the bustle of everyday life.

Guest favourite
A living room features a leather sofa, two vintage armchairs, and a round ottoman, creating a cozy seating arrangement. Natural light enters through large windows framed with sheer curtains. Dark wooden flooring contrasts with the light-colored walls and decorative art pieces are displayed throughout.
Home in Burlington
4.89 out of 5 average rating, 194 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Guest favourite
A bright and spacious bedroom features a comfortable bed with a layered blanket, complemented by decorative pillows. A fan hangs from the ceiling, and artwork adorns the wall above the bed. A small desk and chair are visible in the corner, providing a work area.
Guesthouse in Mount Pleasant
4.91 out of 5 average rating, 125 reviews

The Vernon Street Guest House - Suite 2

Built in 1900 and renovated in 2022, Suite 2 shows little signs of the once quirky old space. Completely private, with all the amenities, it boasts a spacious bedroom, 1 bathroom, a fully equipped kitchen, dining area, living room with a desk for workspace, and a laundry room. While you're here, we hope you are able to relax and enjoy the well lit deck along with a cup of freshly roasted coffee, which we are happy to have provided.

Superhost
A spacious living area features a grey tufted sofa adorned with various textured pillows. A natural woven coffee table sits in front, accompanied by a small decorative plant. Light wooden cabinetry provides a warm backdrop, complemented by a stylish mirror and dark furniture pieces in the adjoining area.
Apartment in Grandview
5 out of 5 average rating, 3 reviews

Historic schoolhouse apartment

This stylish place to stay is perfect for short stays or longer term work needs. Quiet in a small town. Spacious, attention to style and detail. This 2nd floor apartment has an incredible view especially at sunset. Access to workouts in the gym, coin laundry, or outdoor seating in the shade. No smoking in the building. No pets. Friendly, local owners will make your stay as comfortable as possible.

Top guest favourite
The kitchen features modern white cabinetry with black hardware and a marble countertop. A stainless steel refrigerator and oven are visible, along with a dark backsplash. An island with a sink and a black faucet provides additional prep space.
Loft in Fort Madison
4.95 out of 5 average rating, 174 reviews

Beautiful Riverview Studio- steps away from Depot

Enjoy an exclusive view of the River, the FM Train Depot and Old Fort Madison from this 2nd floor true-studio apt. The space has modern décor and all of the comforts of home. Railfans will enjoy the trains and river fans will enjoy the unique east-west river movement. There will be train sounds! The space comfortably sleeps two adults in its queen size Murphy bed. Please reach out with any questions.

Top guest favourite
A spacious kitchen and dining area features light wood cabinets and stainless steel appliances. A small dining table with chairs is positioned next to the kitchen. Natural light enters through a window, illuminating the warm hardwood flooring. Stairs lead to the upper level.
Loft in Burlington
4.98 out of 5 average rating, 151 reviews

Studio in Downtown Burlington with river view

Exposed brick walls. Very comfy bed and 1200 thread count sheets. 2 TVS and wifi. Washer and dryer. Kitchen fully stocked. Located in Historic Downtown Burlington 1 block form the Mississippi River. Walking distance to several restaurants and pubs, Snake Alley(the crookedest street in the world), the public library, Memorial Auditorium, and North Hill park.

Top guest favourite
A wooden ramp leads to a white door, framed by two wall sconces. The exterior is clad in light brown siding, while a small decorative wreath hangs on the door. Windows on either side provide additional light to the entrance.
Apartment in Kalona
4.99 out of 5 average rating, 171 reviews

Private Apartment in the Country

Our apartment in the country is located approximately 4 miles from the main highway on a gravel road. The apartment is attached to our farmhouse but it has its own private entrance and the apartment is all your own space.

Top guest favourite
A black mailbox stands on a white post displaying the address '306 N. 2nd St.' The mailbox is wet from recent rain, with a grassy area surrounding it and a road visible in the background. Trees line the street, contributing to a quiet, residential setting.
Home in Oquawka
4.98 out of 5 average rating, 109 reviews

The Little House

The Little House started as a cabin in the early 1900’s. A refreshed cozy getaway in a great little river town. Restaurants, bars and river access are walkable or close drive. Plenty of room to park boat etc.

Popular amenities for Wapello vacation rentals

  1. Airbnb
  2. United States
  3. Iowa
  4. Louisa County
  5. Wapello