
Guesthouse vacation rentals in Anderson County
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Top-rated guesthouses in Anderson County
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Anderson County guesthouses
Family-friendly guesthouses

Holly Hideaway! 10 Highway miles to Clemson U!

1 bedroom lake front apartment with gorgeous views

Camper at Hickory Lodge and Guesthouse

Private-Lake getaway-7 mile view from dock

Home on the farm

Finished Room over Garage (FROG) on Reedy River

Scenic Loft in the Woods

La Bella Farm
Guesthouses with a patio

Spacious and Tranquil Studio

One Particular Cove ... on Lake Hartwell

Charming Waterfront Guest House

Country Escape on 11 acres-short drive to Clemson

Downtown Clemson Guest Suite!

Adorable Cottage 2 mi. from Death Valley

The Honey Flat

Vacation Home Clemson and Lakes
Guesthouse rentals with a washer and dryer

Gameday guest home near Death Valley

Clemson Carriage House - NEW!

Hartwell Hideway

Quaint guest cottage in Upstate

Pine Trees Rest

The Cottage at Keowee Hollow

Paradise Point on Lake Hartwell

Beautiful Luxury home on Lake Hartwell by Clemson
Destinations to explore
- House rentals Anderson County
- Rentals with a washer and dryer Anderson County
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- Rentals with a fireplace Anderson County
- Family-friendly rentals Anderson County
- Rentals with lake access Anderson County
- Rentals with outdoor seating Anderson County
- Apartment rentals Anderson County
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- Rentals with pools Anderson County
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- Waterfront rentals Anderson County
- Rentals with breakfast Anderson County
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- Fitness-friendly rentals Anderson County
- Rentals with a patio Anderson County
- Private suite rentals Anderson County
- Cabin rentals Anderson County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Black Rock Mountain State Park
- Gorges State Park
- Tugaloo State Park
- Mountaintop Golf & Lake Club
- Table Rock State Park
- Tallulah Gorge State Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Victoria Bryant State Park
- Old Edwards Club
- Victoria Valley Vineyards
- Discovery Island
- Haas Family Golf
- Chattooga Belle Farm
- Wellborn Winery
- City Scape Winery