Vacation rentals with a patio in Clayton County

Ohio Street Retreat- hot tub, massage chair, pool

After a fun day in The Driftless Area, come relax and unwind in Prairie du Chien. Beautifully decorated 2 bedroom home with a spacious kitchen, large island, dishwasher, washer/dryer & 5' walk in shower. We supply all cooking/baking items/utensils so all you need are your food, drinks and ingredients. Full high-speed internet with smart TVs in both bedrooms and living room. Outdoor pool (seasonal), hot tub and massage chair. We love dogs too, so we provide a dog run (there is a pet fee).

Main St. McGregor! Beautifully updated sleeps 10

Welcome to your perfect getaway! This fully furnished home on Main St. is just a short walk from the Mississippi River and the charming, shop-filled downtown. Ideal for couples, families, fishermen, and hikers, it's a year-round retreat—whether you're enjoying the river in summer, taking in the fall colors, or hitting the trails for snowmobiling or ice fishing in winter. Close to Prairie du Chien, Pikes Peak State Park, Effigy Mounds, and just a 20-minute drive to Yellow River Forest.

American House 1854- Steamboat Landing Suite

The whole group will be comfortable in this spacious and unique boutique hotel. The American House, built in 1854 is the oldest standing building in the city of McGregor! Dr. Lucy Hobbs the first woman to graduate a dental college in the world had her dental office in this building from 1862-1865! The building is on the National Registry of Historic Places and offers a one of a kind experience you can’t find anywhere else! Enjoy the best view of the Mississippi in all of McGregor!

Cozy Casita

A peaceful little place to rest and refresh while visiting family and friends or exploring the driftless region of NE Iowa and SW Wisconsin. Nestled in the bluffs on the western bank of the Mississippi you'll be only a couple minutes from the bridge to Prairie du Chien and all the other places of interest up and down both sides of the river; including Pikes Peak State Park, Effigy Mounds, Wyalusing State Park and Cabela's just to name a few.

Roofscape Retreat

Now renting the entire house! Previously offered as a partial rental, this listing has been updated to include exclusive access to the full home, including all bedrooms, bathrooms, kitchen and outdoor areas. Enjoy 4 bedrooms, 2 living rooms, full kitchen, rooftop patio, garage, and laundry. Steps from parks, pool, fishing, and the Mississippi River. Perfect for families or groups seeking comfort, space, and a central Guttenberg location!

1st Fl 2BR Downtown + 2 Pkg

Suite C is a unique first-floor 2BR in downtown Elkader, built with reclaimed local materials: barn board walls, corrugated metal ceilings, a kitchen backsplash made from old HVAC ductwork, and bedroom windows salvaged from a home lost in the 2008 flood. The bathroom features rustic metal from area barns. Powered entirely by solar, this suite blends history, sustainability, and modern comfort—just steps from shops, parks, and dining.

McGregor Bedside Manor

Spacious two bedroom, two full bath ranch style home in the heart of McGregor, Iowa, within walking distance to local shops and the Mississippi River. Large driveway to park your car/truck and boat. There is a full kitchen, dining area, laundry room, work desk, and covered deck where you can sit and relax with your coffee or a cool drink. 75 inch smart TV in the living room, as well as one in each bedroom.

Just Enjoy this Moment(JEM) apartment, Elkader

The 106 1st Street apartment is close to everything in down town Elkader, Iowa, this makes it easy to plan your visit. The cozy apartment has no stairs, which makes the space easy living with your stay. There is a hidden court yard that guest can use, seating for all six of the guest. The front porch is very inviting aswell. Come and enjoy this space while staying in Elkader.

Grandma’s Guttenberg Getaway

Forget your worries in this spacious and serene space. Grandma’s Guttenberg Getaway is a beautiful home located right across from the mighty Mississippi River. This beautiful location has a spectacular view, and is located in a quiet quaint neighborhood. It is within walking distance of the historic downtown district and one block from the south boat landing.