Villa vacation rentals in Colón Province

Find and book unique villas on Airbnb

Top-rated villa rentals in Colón Province

Guests agree: these villas are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Superhost

Villa in Panamá

4.79 out of 5 average rating, 24 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Villa in Panamá

4.82 out of 5 average rating, 56 reviews

Villa La Vista-Panama's majestic mountain hideaway

Welcome to our Villa in Panama's Chagres National Park! We have installed a brand new spa heater in our pool (20Nov24) to enjoy breathtaking views of the surrounding mountain range. Take a dip in our stunning infinity pool, offering picturesque landscapes. Ultimate relaxation during sunset evenings in our inviting hot tub. A gym station you can stay fit. Jefferys Tamarin monkeys at our feeding station. Unwind in a hammock or enjoy a romantic poolside swing. Relax on the outdoor bar stools.

Top guest favourite

Villa in Panamá

5 out of 5 average rating, 11 reviews

Villa El Cangrejo

Bienvenidos a Villa El Cangrejo, un refugio premium en el corazón de la ciudad. Con 800 m², esta propiedad es ideal para 14 personas. Ofrece 7 dormitorios, 7 baños, cocina completamente equipada, piscina, gimnasio y cancha de baloncesto. Disfruta de una sala de cine privada, amplia terraza de 200 m², patio frontal de 50 m², mesa de ping-pong, air hockey, videojuegos, dardos, futbolito, juegos de mesa y wifi. Vive una estadía inolvidable en un ambiente acogedor y completamente equipado.

Top guest favourite

Villa in Panamá

4.96 out of 5 average rating, 57 reviews

Breathtaking Views Mansion w/King Beds

Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

Villa in Punta Chame

4.9 out of 5 average rating, 31 reviews

Beachfront 5BR Villa in Punta Chame ~Pool ~Rooftop

Relax in this spacious beachfront villa with a private pool, rooftop terrace, and palm-lined path straight to the beach. Perfect for families, groups, or special events — whether you’re sharing BBQ nights, watching sunsets on the rooftop, or simply soaking up the tropical atmosphere. Just 2 hours from Panama City and 5 mins to Punta Chame Beach! • Beachfront Villa with Direct Access • Private Pool + Palm Garden • Rooftop with 360° Sunset Views • Fast Wi-Fi & Dedicated Workspace

Guest favourite

Villa in Punta Paitilla

4.98 out of 5 average rating, 91 reviews

Beautiful House in Panama w/ King Beds + Pool

Welcome to our stunning home located in the heart of Punta Paitilla, Panama. This beautiful property boasts 4 bedrooms, 3.5 bathrooms, 7 beds, and can comfortably accommodate up to 11 guests, making it the perfect choice for families or groups of friends. This property also features a private outdoor pool, where you can soak up the sun and cool off on hot days. For those who like to stay active, there is a gym on-site where you can work out and stay in shape during your stay.

Guest favourite

Villa in Portobelo

4.92 out of 5 average rating, 24 reviews

Villa with pool, soccer field and stream

Quiet and spacious villa in Portobelo, Buenaventura. Enjoy a villa with a giant garden, river, soccer court, pool with waterfall and slide , 2 boyos, barbecue areas, terrace. 1 Master Bed with King Bed and Private Bathroom 2 bedrooms with 2 full beds. 1 bathroom in the room. 1 bathroom in the pool area and external shower. Living Room, Dining Room. Cable TV. Equipped kitchen. Hammocks. * The house is equipped with beds for 10 people, bring air mattresses with sheets.

Guest favourite

Villa in Portobelo

5 out of 5 average rating, 71 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top guest favourite

Villa in Punta Chame

4.97 out of 5 average rating, 129 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Superhost

Villa in Juan Gallego

4.81 out of 5 average rating, 27 reviews

Fantastic KasaKai Villa

Nestled as the prime choice for beachfront living near Panama City, this exclusive Villa boasts unparalleled views of the Caribbean Sea. With a private entrance to the sea and a verdant green area for relaxation or private barbecues, it offers the epitome of luxury for discerning guests seeking a nature-infused escape. Perfectly blending tranquility with top-tier amenities, it's an oasis for those craving the serenity of waterfront living.

Superhost

Villa in Altos del Maria

Luxurious B&B house in Altos del Maria

No detail is overlooked at this charming and upscale place to stay. Certainly! When it comes to finding a luxury villa with spectacular views that offers both bed and breakfast, there are several options available. It would be helpful to know the specific location you have in mind so I can provide more accurate information. Could you please let me know the destination where you would like to find such a villa

Guest favourite

Villa in Cacique

5 out of 5 average rating, 43 reviews

FACING THE SEA Cacique (Portobello Park)

In the middle of the Portobello National Park (access only by 4x4, AWD 4-wheel drive) nestled at the top of the hill, between sky and sea, away from prying eyes, in the front row, a very private cozy love nest to rest and disconnect (as a couple or with friends), comfortable, bright (large and high bay windows), spacious, fresh (central air conditioning), witness to a grandiose show that awaits you...!