Guesthouse vacation rentals in Great Smoky Mountains

Find and book unique guesthouse rentals on Airbnb

1 of 3 pages
1 of 3 pages

Popular amenities for Great Smoky Mountains guesthouses

Family-friendly guesthouses

Guest favourite

Guesthouse in Cosby

4.9 out of 5 average rating, 256 reviews

The Birdhouse - A quiet country apartment In Cosby

Sep. 13 – 20

$168 CAD per night
Guest favourite

Guesthouse in Sylva

4.94 out of 5 average rating, 299 reviews

Amazing view! Heart of All Things Smokies Near WCU

Mar. 2 – 9

$212 CAD per night
Guest favourite

Guesthouse in Waynesville

4.96 out of 5 average rating, 256 reviews

Cozy studio loft in the Blue Ridge Mountains

Oct. 18 – 25

$129 CAD per night
Guest favourite

Guesthouse in Maryville

4.98 out of 5 average rating, 246 reviews

LaLa’s Place a cottage over the 100yr old bridge

Nov. 25 – Dec. 2

$158 CAD per night
Guest favourite

Guesthouse in Sevierville

4.97 out of 5 average rating, 326 reviews

Butterfly Barn in the Smoky Mountains

Jul. 5 – 12

$212 CAD per night
Guest favourite

Guesthouse in Knoxville

4.98 out of 5 average rating, 513 reviews

TreeHouse Haven, Very Private, Great Location

May 22 – 29

$201 CAD per night
Guest favourite

Guesthouse in Candler

4.97 out of 5 average rating, 445 reviews

The Cottage at Maple Hill

May 31 – Jun. 7

$146 CAD per night
Superhost

Guesthouse in Maggie Valley

4.89 out of 5 average rating, 159 reviews

The Guest Tower: Amazing Mountain and Valley Views

Jan. 20 – 27

$288 CAD per night

Guesthouses with a patio

Guesthouse rentals with a washer and dryer

Destinations to explore