
Guesthouse vacation rentals in Greenville County
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Top-rated guesthouses in Greenville County
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Greenville County guesthouses
Family-friendly guesthouses

Clean. Comfortable. Convenient.

Five minute walk to Downtown Greer New Everything!

Private Suite in Downtown Simpsonville

Cozy faux-cabin loft by GSP, BMW

Chic CityFlat-walk to Main St, parking! &pvt patio

1950's Cottage- Close to Downtown & Furman

The Backyard Bungalow On the Trail

Forested Retreat-Scenic Above Garage Suite
Guesthouses with a patio

Guest Cottage with Private Drive

Chic Studio with Private Deck

Country-Clubhouse Tiny Home. Close to downtown!

Serene 2BR Retreat on 11 Acres-Family/Pet Friendly

Fun, cozy cottage for two w/games, deck in Easley

Sugar Creek Retreat

2BR Guesthouse Retreat Near Furman w/ Pond Views

Historic Earle Street Guest House
Guesthouse rentals with a washer and dryer

Quiet King Two Bedrm House

Upscale cottage in Downtown Fountain Inn

The oaks cottage

Just off Main near Taylors Mill - Clean & Comfy

Adorable renovated private house w/ parking.

Gorgeous Downtown Studio & Dog Friendly!

Charming 1BD/1BA Studio, 4 Miles to Downtown GVL

Beautiful guest house
Destinations to explore
- Private suite rentals Greenville County
- Rentals with an EV charger Greenville County
- Rentals with pools Greenville County
- Rentals with outdoor seating Greenville County
- Pet-friendly rentals Greenville County
- Waterfront rentals Greenville County
- Loft rentals Greenville County
- Rentals with a firepit Greenville County
- Rentals with breakfast Greenville County
- Rentals with a hot tub Greenville County
- Rentals with a patio Greenville County
- Apartment rentals Greenville County
- Townhouse rentals Greenville County
- Farmstay rentals Greenville County
- Fitness-friendly rentals Greenville County
- Condo rentals Greenville County
- Rentals with a fireplace Greenville County
- Rentals with lake access Greenville County
- House rentals Greenville County
- Tiny house rentals Greenville County
- Cabin rentals Greenville County
- Rentals with a washer and dryer Greenville County
- Rentals with an accessible height toilet Greenville County
- Smoking-friendly rentals Greenville County
- Rentals with a kayak Greenville County
- Family-friendly rentals Greenville County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Blue Ridge Parkway
- River Arts District
- Gorges State Park
- Table Rock State Park
- Chimney Rock State Park
- The North Carolina Arboretum
- Mountaintop Golf & Lake Club
- Tryon International Equestrian Center
- Lake Lure Beach and Water Park
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Biltmore Forest County Club
- Vineyards for Biltmore Winery
- Victoria Valley Vineyards
- Woolworth Walk
- Old Edwards Club
- French Broad River Park
- Discovery Island
- Thomas Wolfe Memorial
- Haas Family Golf
- Carl Sandburg Home National Historic Site
- City Scape Winery
- Saint Paul Mountain Vineyards