Vacation rentals in Mayo Lake

Lakefront with Million Dollar Views on HYCO Lake

Get away from the stresses of life with this 3-Bedroom lakehouse with large boathouse. Sleeps 10 people in bedrooms and additional spaces on living room on couches. Breathtaking view of the lake and surrounding. Enjoy the water with included floating water mat or explore the area with our 2 kayaks and 2 paddle boards. Home features 3 bedrooms, 2 full baths, spacious full kitchen, washer/dryer, fire pit, 1,000MBs WIFI, YouTube LiveTV, gas grill , whole house standby generator and other amenities.

Timberwood Tiny Home

Timberwood Tiny Home is a place to rest your head & heart in Efland, North Carolina. The peaceful retreat is down a country road approximately 10-minutes from downtown Hillsborough. The 200 square foot tiny home is on a private corner of 8-acres shared with our main house. It features Scandinavian-style details, two beds, a spacious porch, abundant natural light, a wood-fired hot tub, barrel sauna, cold plunge, and more. There are features of the home that may make it unsuitable for children.

Light-filled Guesthouse Near Duke

Second floor of recently-built garage apartment in a charming, peaceful Durham neighborhood. Twenty minutes to RDU Airport, five minutes to Duke's East Campus and ten minutes to West Campus, we are an easy walk to a range of locally-owned restaurants. Lovely, light-filled apartment has a bedroom, full kitchen and living area, bathroom, private entrance, and patio with seating. Occasionally, we may have first-floor space available at extra cost. Well-behaved pets welcome. See below for fees.

Kerr Lake Amazing Views, Private Dock, Quiet

Peaceful lakefront retreat: Private dock, table, and new solar-lit umbrella (7/28/25). Amenities include a new gas grill (7/28/25), paddleboard, canoe, kayak, cornhole, hammock, firepit, puzzles, books, and games. Enjoy a large deck with two tables and a screened porch with couch—perfect for morning coffee. The home features 3 bedrooms, a loft, 3 full baths, and a dedicated workspace. Ideal for families, friends, or fishing trips. Driveway fits 5 trucks with trailers; boat launch 2 miles away.

Lakefront | Kayaks| SUPs | Hot Tub | Boat Options

Optional brand new pontoon boat rental, see below for details! Enjoy a spacious 3200+ SF home with one of the best docks and views on the lake! Stunning water view, room for many and everything you need for a romantic weekend or large gathering of family and friends. Be ready to relax on the water - feel free to use the canoe, kayaks, stand-up paddle-boards, and much more! Unobstructed view for over half a mile right in front of the house! Peace and tranquility at its' finest. Close to VIR!

Pine Bluff Trails Guest House

This guest house is set on 20 acres of land that is bordered by Hyco Creek on the east and Caswell game land on the south. Great place for privacy and is a close get away for nature lovers, fishermen, hunters, or just a quiet place to escape the city! Direct access to Hyco Creek and the game land is available through the property - you could even kayak into Hyco lake if you wanted! Property has a secured gate for entrance and exit and property is located about 1/4 mile down an access road.

Lakefront Cottage w/ great view and use of dock

The sunlit cottage is perfect place to enjoy the largest lake in Virginia, exploring nearby state parks, the quaint town of Clarksville, or nearby breweries/wineries. The cottage offers an open view of the lake and use of a dock (150 yds from house) for fishing, swiming, docking watercraft or watching the sunset. A great retreat for a small family of 4 or 2 couples. Please indicate the number of guests; parties over 4 must be pre-approved. Reservation must be by an adult (age 21+).

Cozy Cabin in the Countryside

Enjoy a cozy cabin with internet, ac/heat, kitchenette with fridge and microwave. Please note there is no water in the cabin and shower and toilet are located in the bathhouse just a few steps away. This comfortable Cabin has very easy quick access to all amenities including the showerhouse, picnic areas, lawn games, outdoor kitchen. Hottub is open. Property is within minutes of downtown Chapel Hill & Hillsborough, Raleigh, Durham are 20-30 minutes away. No Smoking or Vaping in Cabins

Peaceful tiny house retreat on 30 acre farm

This new tiny house is nestled amongst mature hardwood trees on a 30 acre working family farm in Hillsborough. Quiet your mind and restore your body in the luxurious hot tub or warm up by the cozy fire-pit. Under 10 miles to Hillsborough or Durham, and their many restaurants, breweries and shops. Enjoy the privacy of two secluded wooded acres, surrounded by the sights and sounds of our farm, where we are growing fruits, veggies and mushrooms & caring for our animals and pastures.

Water Front Lake House!

Waterfront home on MAYO LAKE. 2 Bd, 1.5 bath fully furnished . Wi-fi, Smart TVs, Alexa, frig, stove washer/dryer, microwave. Queen-size bed, sleeper sofa and bunk bed. Wrap around porch w/ rocking chairs, swing and 2 picnic tables. Large yard for playing, just feet away from the water and dock, hammock and fire pit. Lots of fishing, single kayak, 2 person kayak, canoe and 2 paddle boats available. PERFECT FOR ANY SEASON LONG OR SHORT STAY. Located on Mayo Lake in Roxboro, NC

Mountain cabin feel on Hyco Lake.

Unwind at this hidden jewel tucked in the woods on Hyco Lake. Forget tiny houses, this “Skinny House” boasts two bedrooms, two baths, a spacious open floor plan, cedar ceilings, fully equipped kitchen, gas grill, solo stove, laundry room. Indoor and outdoor living that is large enough for six adults. Floating dock invites you to spend your days on the lake - swimming, fishing, boating, or just soaking in the views. Canoe, Kayaks, Paddle-boards & life vests provided!

Lakefront Oasis-HotTub | GameRoom | Kayaks | Dock

At Pointe Mayo Lake, discover a serene, rustic retreat by Mayo Lake. Enjoy amenities like kayaks & canoes, private dock, fishing rods, a grill, a hot tub, a game room, and a fire pit. Perfect for avid vacationers, couples, families, groups of professionals, and even your furry friends! We are Pet and Family Friendly! Love what you see but not ready to book? Click the ❤️ "Save" button on the top right to easily find us again and secure your getaway when you're ready!