Vacation rentals in Mayo Lake

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Top-rated vacation rentals in Mayo Lake

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Guest favourite
A large boathouse is visible next to a serene lake, with a wooden dock extending towards the water. A dining table with chairs is positioned on the dock, and vibrant marigolds are seen at the base. The sky features scattered clouds, and lush greenery surrounds the area.
Home in Leasburg
4.94 out of 5 average rating, 128 reviews

Lakefront with Million Dollar Views on HYCO Lake

Get away from the stresses of life with this 3-Bedroom lakehouse with large boathouse. Sleeps 10 people in bedrooms and additional spaces on living room on couches. Breathtaking view of the lake and surrounding. Enjoy the water with included floating water mat or explore the area with our 2 kayaks and 2 paddle boards. Home features 3 bedrooms, 2 full baths, spacious full kitchen, washer/dryer, fire pit, 1,000MBs WIFI, YouTube LiveTV, gas grill , whole house standby generator and other amenities.

Top guest favourite
A fire pit area with several Adirondack chairs surrounds a central space. String lights illuminate the area, creating a cozy evening ambiance. The two-story home is visible in the background, featuring large windows and a spacious deck. Lush trees surround the setting.
Home in Roxboro
4.98 out of 5 average rating, 89 reviews

Private Lakefront Paradise - Paddleboards & Kayaks

*Dogs only allowed with approval from owner. Scroll down to read more.* Beautiful 3 bedroom, 3 bath home on Mayo Lake in Roxboro, NC. Incredible views of the lake. You rarely see anyone on our secluded cove. You can swim, fish, paddleboard, kayak or tie up your boat. House is only 5 minutes from the marina and comes with paddleboards and kayaks and has a fire pit. Large, open kitchen, family room/ entertainment room, ping pong table, and jetted tub. Close to hiking, fine dining, and VIR.

Guest favourite
A white-sided mobile home is shown with a welcoming front porch. A concrete walkway leads to the entry door. Windows are visible, allowing natural light. Green grass surrounds the home, enhancing its connection to the rural landscape.
Home in Semora
4.84 out of 5 average rating, 167 reviews

Scenic Semora Home

This older family home is located in Semora on our family's farm. The home is very secluded and private on a beautiful road. VIR (Virginia International Raceway) is only a 12 minute drive away. Hyco Lake is an 11 minute drive. This makes us perfectly situated between two popular vacation spots. We are about 12 minutes from Milton and 20 minutes from Yanceyville and Roxboro where you can find shopping and restaurants. **Please note this is a very rural home. We do not do long term renters.

Top guest favourite
Adirondack chairs are positioned near a wood-burning fire pit overlooking a serene pond surrounded by lush greenery. The landscape features a walking path leading to a wooden bridge across the water, creating a tranquil outdoor setting.
Apartment in Rougemont
4.95 out of 5 average rating, 210 reviews

Charming Studio #1 "On Farm Time"

New rate on 30+ days rent! Our upstairs Farm Time studio, with full kitchen, is perfect for a quiet get away. Nestled alongside a picturesque pond, this 1-bathroom apartment with queen bed and full sleeper sofa, is a great place to relax. Spend crisp mornings strolling through the green fields or enjoy a fire overlooking the pond at night. There’s also plenty to do in nearby Hillsborough (10 miles) and Durham (18 miles) - museums, parks, markets, and restaurants. RDU Airport (34 miles).

Top guest favourite
Two turquoise lounge chairs are positioned on a wooden dock, providing a serene view of the calm water and surrounding trees. The leaves display autumn hues, reflecting the season's changing colors. A railing runs along the dock, enhancing safety and accessibility to the water.
Cottage in Leasburg
4.81 out of 5 average rating, 201 reviews

Hyco Hideaway

A lakeside retreat to call your own (at least for a little while). This two bedroom, one bath scenic cottage sits on approximately 250 feet of waterfront where you have a lake view from the huge screen porch. An open floor plan with fully furnished kitchen, beds, and full bath will make this an exceptional getaway. Nestled deep in the forest, the dock is accessible by a path that is steep in places or staircase plus steep timber steps with no handrail. Water depth at dock is shallow.

Top guest favourite
A rustic cabin is presented with a welcoming porch supported by sturdy posts. Steps lead up to the entrance, where the surrounding greenery and trees provide a natural setting. An American flag hangs nearby, contributing to the serene atmosphere of the property.
Cabin in Roxboro
4.88 out of 5 average rating, 186 reviews

Water Front Lake House!

Waterfront home on MAYO LAKE. 2 Bd, 1.5 bath fully furnished . Wi-fi, Smart TVs, Alexa, frig, stove washer/dryer, microwave. Queen-size bed, sleeper sofa and bunk bed. Wrap around porch w/ rocking chairs, swing and 2 picnic tables. Large yard for playing, just feet away from the water and dock, hammock and fire pit. Lots of fishing, single kayak, 2 person kayak, canoe and 2 paddle boats available. PERFECT FOR ANY SEASON LONG OR SHORT STAY. Located on Mayo Lake in Roxboro, NC

Guest favourite
The interior space features a warm wooden ceiling and a large Smart TV mounted on the wall. A glass sliding door offers views of the lush greenery outside and the lake beyond, leading to a deck with outdoor seating.
Home in Leasburg
4.93 out of 5 average rating, 155 reviews

Mountain cabin feel on Hyco Lake.

Unwind at this hidden jewel tucked in the woods on Hyco Lake. Forget tiny houses, this “Skinny House” boasts two bedrooms, two baths, a spacious open floor plan, cedar ceilings, fully equipped kitchen, gas grill, solo stove, laundry room. Indoor and outdoor living that is large enough for six adults. Floating dock invites you to spend your days on the lake - swimming, fishing, boating, or just soaking in the views. Canoe, Kayaks, Paddle-boards & life vests provided!

Top guest favourite
Home in Roxboro
4.93 out of 5 average rating, 118 reviews

Lakefront Oasis-HotTub | GameRoom | Kayaks | Dock

At Pointe Mayo Lake, discover a serene, rustic retreat by Mayo Lake. Enjoy amenities like kayaks & canoes, private dock, fishing rods, a grill, a hot tub, a game room, and a fire pit. Perfect for avid vacationers, couples, families, groups of professionals, and even your furry friends! We are Pet and Family Friendly! Love what you see but not ready to book? Click the ❤️ "Save" button on the top right to easily find us again and secure your getaway when you're ready!

Guest favourite
Home in Roxboro
4.88 out of 5 average rating, 24 reviews

Mayo Lake | Hot Tub | Kayaks | Kids Area - Getaway

Welcome to your perfect getaway at our charming lake house on Mayo Lake! Enjoy a peaceful lake view and lots of amenities in a tranquil setting. With a floating dock, kayak and canoe, plenty of land to stretch your legs, a fire pit to gather around, a hot tub, and even a fully stocked entertainment room (including miniature pinball), there's plenty to do! Ideal for relaxation and adventure, our lake house offers the perfect blend of comfort and entertainment.

Top guest favourite
A serene lake is observed from a wooden dock, with calm waters reflecting surrounding greenery and a clear sky. The shoreline is lined with trees, creating a tranquil atmosphere. Ripples gently disturb the water's surface, highlighting the lake's peaceful environment.
Home in Roxboro
5 out of 5 average rating, 92 reviews

Long’s Lakehouse

Relax with the whole family at this peaceful waterfront property. It is a 2 bedroom, 2 bathroom house with one queen bed, one full bed, and a pull out sofa! The kitchen is fully stocked with a coffee pot, utensils, pizza pan, crock pot, skillet, pots , pans, baking sheets, toaster, oven and microwave! Bedrooms and living room have smart tvs. WiFi available! Enjoy the kayaks, lots of fishing, grilling, and fire pit! There is something for here for everyone!

Guest favourite
A cozy living area features warm wooden paneling and an inviting brown leather sofa. Bright blue cabinetry contrasts with the darker kitchen appliances. Natural light fills the space, highlighting a colorful area rug and providing a welcoming atmosphere for relaxation.
Guesthouse in Rougemont
4.9 out of 5 average rating, 209 reviews

Cozy Cottage on a Hilltop

Private cottage for people & pets (please indicate what kind of pets you are bringing). The cottage offers beautiful views of the countryside overlooking the pastures. There is a private seating area by the side of the cottage where you can enjoy amazing sunrises with a cup of coffee or cocktails in the evening. My 2 acres of property offer privacy and quiet atmosphere to enjoy a peaceful retreat. Please let me know the ETA the day of the arrival.

Guest favourite
A charming farmhouse is positioned on 28 acres, featuring a large front porch with a path leading to the entrance. Lush greenery surrounds the home, and a gravel driveway extends from the foreground to the house, providing an inviting outdoor space.
Home in Roxboro
4.9 out of 5 average rating, 138 reviews

Historic Barton’s Mill Farmhouse

A quiet farm house located on 28 acres of family property. Seconds from 501 and within a 5 minute drive or less to local shopping and dining. Merely 15 minutes from north Durham, 20 minutes drive to hyco and Mayo lake 30 minutes from RTP. Located with in 5 miles of the Raleigh regional airport in person county and 30 minutes from VIR with plenty of room for trailer parking. 45 mins from Caesars Casino in Danville VA! This home truly has it All!

Popular amenities for Mayo Lake vacation rentals