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Vacation rentals in Mesopotamia

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A spacious wooden bedroom features a king bed adorned with light bedding, complemented by textured walls and a rustic wood ceiling. A colorful hammock hangs across the room, and natural light filters in through a window, enhancing the cozy ambiance.
Treehouse in Retiro
4.89 out of 5 average rating, 110 reviews

A wooden cabin in the El Retiro Antioquia forest

Imagine sleeping in a wooden cabin in a king-size bed with the lull of the river's sound. When you wake up you will feel like you are in a treehouse overlooking the snowflakes full of birds, going down to the garden with bare feet, having breakfast on the deck and seeing the horizon. During the day, walk, go to the river and the waterfall, get to the stone bathroom and the whirlpool, sit in the hammock, read, and at night light the fireplace (salamander), have a glass of wine at the kitchen counter with your partner, family, and friends.

Top guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny homes in Guatape
4.98 out of 5 average rating, 618 reviews

Foresta: Modern cabin with views of the rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour. You choose!

Top guest favourite
An outdoor deck area features a hammock hanging beside a small jacuzzi, complemented by a dining table for four. Large sliding doors provide a view into the interior space, where a cozy atmosphere is highlighted by warm lighting and natural wood elements.
Villa in Rionegro
4.95 out of 5 average rating, 177 reviews

Sweet Helen Llanogarden

Sweet Helen Llanogarden situado en el Tablazo-Llanogrande, a tan solo 10 minutos del aeropuerto internacional José Maria Córdova de Rionegro Antioquia, cerca a restaurantes, centros de eventos y malls, en el cual ofrecemos servicios de alojamiento para familias, amigos, parejas y viajes de negocios. En Sweet Helen Llanogarden encontrarás el espacio para pasar una estancia segura, tranquila y divertida, esta vez, rodeada de naturaleza y confort en la zona más exclusiva del oriente antioqueño.

Guest favourite
The Tiny House is surrounded by lush greenery, perched atop a hillside. A spacious deck wraps around the structure, offering panoramic views of the surrounding mountains and valleys. The landscape showcases vibrant foliage, enhancing the connection with nature.
Tiny homes in Medellín
4.94 out of 5 average rating, 324 reviews

Tiny House with a view of the sunrise & squirrels

✨ Welcome to Cubo Nube At La Cordillera Santuario Natural, we invite you to disconnect from the noise and reconnect with nature. A unique space for romantic getaways or long stays, with all the comforts for a true disconnection. 🔥 Perfect for: - Birdwatching, spotting squirrels, and more wildlife 🐿️🕊️ - Couples seeking an intimate retreat 💕 - Digital nomads with fast WiFi 💻 - Photography and tranquility lovers 📸 - Resting in a king-size bed 🛏️ - And enjoying total privacy 🌿✨

Superhost
Cabin in Medellín
4.93 out of 5 average rating, 227 reviews

Cocuyos Chalet in Vereda

Just 40 minutes from Medellín, our chalets combine the rustic charm of Santa Elena with all the modern comforts you need. Each chalet is fully furnished and equipped, featuring high-speed internet, hot water, and private parking. You’ll have easy access to public transportation, local shops and markets, as well as cafés and restaurants within walking distance. Perfect for romantic getaways, remote work, or simply reconnecting with yourself in a natural and cozy setting

Superhost
Cabin in Rionegro
4.92 out of 5 average rating, 59 reviews

The Ultimate Group House w/ Hot Tub & Amazing View

About this space 🌟 2 bedrooms, each with a double bed & private bathroom 🛏️ Double sofa bed in the living room 🛋️ Bathrooms with hot water & fresh towels 🚿 Living room with Smart TV & WiFi 📺 Private jacuzzi for relaxation 💦 Fully equipped kitchen 👩‍🍳 Gas BBQ grill for cookouts 🍖 Catamaran net, dining table & spacious deck/terrace 🌞 Private parking space 🅿️ Portable heater available 🔥 Breakfast available upon request, prepared by our staff with extra cost 🍳

Top guest favourite
Cabin in Rionegro
4.95 out of 5 average rating, 326 reviews

Nature & View | Cabin with a view

Nature & View just 8 min from JMC Airport Ideal for couples or travelers in transit. Our cabin offers a view of the valley, a quiet atmosphere, self check-in, an equipped kitchen, fast wifi, and all the comforts to relax. For your convenience, there are restaurants with home delivery and inside the accommodation you can buy cold drinks and snacks when you need them. 🚘 Trusted Uber driver Relax, order your favorite food and enjoy the view. Book your date!

Top guest favourite
A covered jacuzzi is visible in the foreground, with bubbling water inviting relaxation. In the background, two hammocks are strung between trees, set against a lush green landscape and a wooden structure that complements the serene setting.
Farm stay in Retiro
4.99 out of 5 average rating, 149 reviews

"Authentic Antioquia Estate with All the Comforts"

Finca Sietecueros - Natural Refuge and Comfort in One Place Escape to Finca Sietecueros, a country house surrounded by forests and mountains. Relax in the jacuzzi, enjoy the hammocks under the trees, or share stories in the campfire area under a starry sky. Ideal for couples, families, and friends seeking peace, nature, and comfort in a unique setting. Book your stay and live an unforgettable experience in contact with nature!

Top guest favourite
Chalet in Antioquia
4.96 out of 5 average rating, 319 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Guest favourite
A wooden deck features a private jacuzzi surrounded by lush greenery and vibrant palm trees. Scenic hills and a colorful sky create a serene backdrop, while outdoor seating is visible nearby, inviting relaxation in nature.
Cabin in El Peñol
4.95 out of 5 average rating, 128 reviews

Sun Palm Cabin: Nature and Comfort in El Peñol!

Discover an exceptional retreat surrounded by nature, where every detail is designed to offer you an unforgettable experience. This cabin combines elegance and comfort. Relax in your private jacuzzi while enjoying breathtaking panoramic views in a serene environment. Perfect for a romantic getaway or rejuvenating vacation, you will find the ideal harmony between privacy and natural beauty. Your perfect escape awaits!

Guest favourite
The cozy cabin is nestled in a lush green landscape, illuminated by warm outdoor lights. A wooden deck features comfortable seating, overlooking the serene surroundings. Large windows provide a glimpse of the interior, showcasing a warm and inviting space harmonized with nature.
Farm stay in Rionegro
4.95 out of 5 average rating, 298 reviews

Casa del Leñador | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.

Guest favourite
A private terrace features a softly illuminated jacuzzi, surrounded by wooden decking, offering expansive views of the city at night. The structure includes large glass doors, enhancing visibility to the inside space while creating a seamless transition between indoor and outdoor areas.
Cabin in Sabaneta
4.94 out of 5 average rating, 124 reviews

eDeensabaneta Ibiza cabin

This unique place has a style all its own. Enjoy incredible views on the terrace while relaxing in the Jacuzzi, or enjoy the cozy cabin in an area very close to Sabaneta with the attention you deserve. This cabin is part of a family dream called eDeen, where our priority is to make every moment unique, providing the best personalized attention to make guests feel at home.

Popular amenities for Mesopotamia vacation rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia