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Vacation rentals in Mesopotamia

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Top-rated vacation rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A spacious wooden bedroom features a king bed adorned with light bedding, complemented by textured walls and a rustic wood ceiling. A colorful hammock hangs across the room, and natural light filters in through a window, enhancing the cozy ambiance.
Treehouse in Retiro
4.89 out of 5 average rating, 115 reviews

A wooden cabin in the El Retiro Antioquia forest

Imagine sleeping in a wooden cabin in a king-size bed with the lull of the river's sound. When you wake up you will feel like you are in a treehouse overlooking the snowflakes full of birds, going down to the garden with bare feet, having breakfast on the deck and seeing the horizon. During the day, walk, go to the river and the waterfall, get to the stone bathroom and the whirlpool, sit in the hammock, read, and at night light the fireplace (salamander), have a glass of wine at the kitchen counter with your partner, family, and friends.

Guest favourite
An aerial view showcases a secluded property surrounded by greenery, softly illuminated by outdoor lights at dusk. The house is positioned on a hill, while paths lead to small seating areas enhanced by tropical plants. The inviting layout suggests a peaceful retreat.
Cabin in Peñol
4.9 out of 5 average rating, 101 reviews

An impressive house with a Jacuzzi

Take it easy at this unique and tranquil getaway. This house in a subdivision with 3 spacious rooms, a Jacuzzi, a barbecue, access to the dam, and a stunning view of the Peñol stone ★"My wife explored the options and feels that your beautiful villa is her favorite in El Peñol." - Marcela, September 15 Exclusive condominium with few houses which will provide security during your stay, large terrace for your meetings and enjoyment with family or friends. Very safe and comfortable place Newly furnished☞ house.

Guest favourite
Tiny homes in Cocorná
4.95 out of 5 average rating, 37 reviews

Cabin with jacuzzi, private river and natural pool

Enjoy incredible privacy in the beautiful nature of Cocorná. Relax in the jacuzzi or enjoy the beautiful river with a private terrace next to a naturally created pool that belongs exclusively to this property. The cabin features a beautiful bathroom, a king size bed, Wi-fi, a TV with Netflix, and a kitchen equipped with all cooking utensils including a barbecue. We also organize various activities including paragliding and rafting. We offer transportation. Breakfast is included! (to prepare)

Top guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny homes in Guatape
4.98 out of 5 average rating, 630 reviews

Foresta: Modern cabin overlooking the Rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us, or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the Rock and do kayaking, jet-skiing, wakeboarding, sailing, paraglading, horseback riding, hiking, helicopter tours or ATV rides. You choose!

Top guest favourite
A modern structure emerges from lush greenery, framed by vibrant plants and a manicured lawn. Large glass doors lead to a spacious deck, offering a view of the mountains and a colorful sky. Pathway stones create a welcoming entrance.
Home in La Ceja
4.94 out of 5 average rating, 54 reviews

Country house, excellent location, beautiful view!

We invite you to enjoy a beautiful space surrounded by nature, with all the amenities you need to relax and unwind. You will feel like you are right at home. Ideal location for remote work (digital nomads) and extended stays. Just 10 minutes from La Ceja, 45 minutes from the international airport, and 1 hour from Medellín. Pets are welcome. In addition, we offer yoga classes, Ayurvedic therapies (Abhyanga/Swedana), and tennis lessons. Perfect place for "slow" tourism!

Top guest favourite
Cabin in Rionegro
5 out of 5 average rating, 28 reviews

Selvva suites | luxury cabin in a forest + jacuzzi

Escape to SELVVA SUITES, a luxury retreat immersed in the tranquility of a native forest, just 50 minutes from Medellín. Located on the Llanogrande–La Ceja road, only 15 minutes from Llanogrande mall and 20 minutes from JMC Airport in Rionegro. Enjoy a King-size bed and a private jacuzzi surrounded by nature. Private parking with easy access for any type of vehicle. ⚠️ ✈️We are in an area with air traffic, and airplane noise can be heard. 🐾 Pet friendly

Top guest favourite
Cabin in Rionegro
4.95 out of 5 average rating, 335 reviews

Nature & View | Cabin with a view

Nature & View just 8 min from JMC Airport Ideal for couples or travelers in transit. Our cabin offers a view of the valley, a quiet atmosphere, self check-in, an equipped kitchen, fast wifi, and all the comforts to relax. For your convenience, there are restaurants with home delivery and inside the accommodation you can buy cold drinks and snacks when you need them. 🚘 Trusted Uber driver Relax, order your favorite food and enjoy the view. Book your date!

Superhost
An outdoor deck is shown, featuring a wooden table surrounded by woven chairs. A fire pit sits on one side, and a large glass structure serves as an entrance, providing views of the lush hillside. The cabin's facade showcases a combination of wood and glass.
Cabin in La Ceja
4.85 out of 5 average rating, 52 reviews

Casi Cielo! Heaven's Edge

Nestled 7,000 feet high, our tranquil cabin promises breathtaking mountain and waterfall vistas. This retreat, perfect for romantic getaways or family escapades, enchants with its warming fire pit and rejuvenating hot tub. Experience the stunning wilderness, bask in the magnificent scenery, and craft unforgettable memories. This is not just a stay, but an experience enveloped in serene beauty, embracing the extraordinary amidst the ordinary. (500 characters)

Top guest favourite
Farm stay in Cocorná
5 out of 5 average rating, 39 reviews

Bali-style cabin with forest and private river

Bali-style cabin with more than 2 hectares of private forest and river, hot Jacuzzi, wifi, spring climate, combining luxury and nature, deck next to the river, campfire, cinema-type video projector, shower with a view of nature, work and reading area, beautiful night lighting, kitchen and BBQ area, sun loungers and many other details designed to give you a unique experience and invite you to slow down and reconnect with yourself and nature

Top guest favourite
A charming chalet is depicted beside a serene natural lake, framed by lush greenery and vibrant aquatic plants. The structure features rustic wooden details, large windows, and an expansive deck, inviting outdoor relaxation and enjoyment of the tranquil surroundings.
Cabin in Santa Elena
4.99 out of 5 average rating, 170 reviews

Lake Chalet | Private Jacuzzi + Nature

🌿 Chalet del Lago – St. Helena Escape to a natural retreat with a private lake, large windows and a peaceful setting. With very complete equipment and distribution. Just 10 minutes from the main park, enjoy the birdsong, the sound of water and the cool climate of the Antioquia countryside. Ideal for couples, families or a relaxing getaway. Nature, tranquility and unforgettable moments in one place. 💛✨ ✅ We are pet friendly🐶🐈

Top guest favourite
Chalet in Antioquia
4.96 out of 5 average rating, 324 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Guest favourite
Farm stay in Rionegro
4.95 out of 5 average rating, 300 reviews

Casa del Leñador | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.

Popular amenities for Mesopotamia vacation rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia