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Vacation rentals in Mesopotamia

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Top-rated vacation rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favourite
A panoramic view captures the surrounding mountains and lush landscapes, with a mix of greenery and water bodies visible below. La Piedra de Peñol is prominently featured on the right, overlooking the expansive reservoir and hills stretching into the distance under a bright blue sky.
Treehouse in El Peñón de Guatapé
4.94 out of 5 average rating, 123 reviews

Treehouse in El Peñol - 360° views of stone

Enjoy the sounds & privacy of nature at this unique cabin in the trees ATOP the closest mountain to Piedra de Peñol. *IMPORTANT NOTES!* Though nicely located in nature, IT'S A TREEHOUSE CABIN IN & ON TOP OF MOUNTAINS, not a resort downtown. *PRICES CHANGE DEPENDING ON NUMBER OF PEOPLE (AB&B's POLICY!) Located as high as La Piedra de Peñol with better views than from the rock as you're able to see it as well! The cabin's isolated away from roads, noises of civilization & surrounded by reserves.

Top guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny homes in Guatape
4.98 out of 5 average rating, 559 reviews

Foresta: Modern cabin with views of the rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour. You choose!

Top guest favourite
Tiny homes in Cocorná
5 out of 5 average rating, 12 reviews

luxury cabin with sauna, jacuzzy and private river

Enjoy the beautiful nature and tranquility of this luxurious accommodation with a sauna, jacuzzi, and private river terrace. Just 75 minutes from Medellín, this beautiful cabin is easily accessible by any car or motorcycle. The spectacular surroundings of Cocorná have much to offer, including paragliding, rafting, quad biking, and hiking trails along beautiful rivers. We are happy to assist you with transportation or booking activities. We offer private transport from the airport!

Guest favourite
An outdoor terrace is presented, featuring a jacuzzi, a barbecue grill, and lounge seating. The space contains several chairs arranged around a fire pit, along with a table for dining. The area is brightened by natural light and offers views of the surrounding environment.
Condo in El Carmen de Viboral
4.92 out of 5 average rating, 240 reviews

Modern and Cozy Condo El Cóndor -Carmen Viboral

Beautiful and cozy apartment in the center of Carmen de Viboral with 1 well-equipped master bedroom, a spacious and bright living room with sofa bed, access to terrace, fully equipped kitchen, bathroom and jacuzzi. This apartment has a beautiful view of the town and excellent areas to share as a couple or as a family. It is located 1 minute from the main park, close to pharmacies, ATMs, supermarkets, restaurants and others. This is the preferred place to rest and relax.

Guest favourite
Cabin in Rionegro
5 out of 5 average rating, 31 reviews

The Ultimate Group House w/ Hot Tub & Amazing View

About this space 🌟 2 bedrooms, each with a double bed & private bathroom 🛏️ Double sofa bed in the living room 🛋️ Bathrooms with hot water & fresh towels 🚿 Living room with Smart TV & WiFi 📺 Private jacuzzi for relaxation 💦 Fully equipped kitchen 👩‍🍳 Gas BBQ grill for cookouts 🍖 Catamaran net, dining table & spacious deck/terrace 🌞 Private parking space 🅿️ Portable heater available 🔥 Breakfast available upon request, prepared by our staff with extra cost 🍳

Top guest favourite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 100 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * 143 m² / 1539 ft² house size * Private Deck. Views of valley/Rionegro/Airport * Views of mountains * Privacy gate. Alarm. Parking for 5+ Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Top guest favourite
A modern structure emerges from lush greenery, framed by vibrant plants and a manicured lawn. Large glass doors lead to a spacious deck, offering a view of the mountains and a colorful sky. Pathway stones create a welcoming entrance.
Home in La Ceja
4.93 out of 5 average rating, 44 reviews

Country house, excellent location, beautiful view!

We invite you to enjoy a beautiful space surrounded by nature, with all the comforts so you can relax and relax. You will feel like you are right at home. Ideal place for telecommuting (digital nomads) and long stays. Just 10 minutes from La Ceja, 45 minutes from the international airport and about 1 hour from Medellin. Pets are welcome. Additionally we offer Yoga classes and Ayurvedic therapies (Abhyanga/Swedana). Perfect place for "slow" tourism!

Top guest favourite
The cozy cabin is nestled in a lush green landscape, illuminated by warm outdoor lights. A wooden deck features comfortable seating, overlooking the serene surroundings. Large windows provide a glimpse of the interior, showcasing a warm and inviting space harmonized with nature.
Farm stay in Rionegro
4.95 out of 5 average rating, 279 reviews

Lumberjack's House | Secluded nature retreat

Cabin 🪓 Retreat – The Lumberjack's House is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend or work remote in a distraction-free environment. Wake up to the singing of the birds at sunrise and enjoy a fire on the deck at sunset. In Retiro Cabin you will have total independence and an unparalleled view of the countryside in the Antioquia East.

Top guest favourite
Chalet in Antioquia
4.96 out of 5 average rating, 283 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Top guest favourite
A contemporary lake house is nestled on the shore, featuring a striking triangular design. Lush greenery surrounds the property, with serene lake waters reflecting the sky. Outdoor decking offers a scenic view, and moored boats add to the tranquil atmosphere of the location.
Island in Guatape
4.99 out of 5 average rating, 107 reviews

Stunning Lake House • Jacuzzi • Amazing Views

Welcome to Acua Lake House, your private lakeside retreat. A romantic escape with the most stunning views of Guatapé and La Piedra del Peñol. Enjoy a private jacuzzi, golden sunsets from the terrace, and calm-water sunrises. Every detail is designed for comfort, intimacy, and a deep connection with nature. Perfect for couples. Also suitable for small families. 🌿 Let us surprise you. @acuaexperience

Top guest favourite
A cabin is positioned on stilts surrounded by greenery, offering a panoramic view of the mountains. Nearby structures are visible on the hillside, set within lush gardens and fields that suggest agricultural activity. The sky is partly sunny, highlighting the natural beauty of the location.
Hut in El Carmen de Viboral
4.93 out of 5 average rating, 27 reviews

Cielo Verde Cabin

A cozy cabin 10 minutes from the main park of El Carmen de Viboral with incredible panoramic views of eastern Antioquia, views of crops, starry sky, and access to a forest with eco-friendly trails to explore. Equipped kitchen services, full bathroom overlooking the forest, barbecue, hammocks and hammock net. Clarification: The cabin is located 1300 meters by unpaved road from the main road.

Top guest favourite
A floating house showcases a thatched roof illuminated in warm tones, situated on a wooden deck. Two sun loungers are positioned beside a tranquil waterway, with a kayak resting nearby. Lush greenery outlines the serene landscape under a twilight sky.
Houseboat in Peñol
5 out of 5 average rating, 67 reviews

Floating House-Jacuzzi-WIFI-Kayak-El Peñol

Lakeside Paradise – Floating House with Jacuzzi, Kayak and Mountain Views Immerse yourself in the serenity of the KAUBA house on the water. Located in the lake of El Peñol. A private floating dream escape that combines the tranquility of the water with comfort. It is an oasis of relaxation, surrounded by stunning landscapes that will make you feel in harmony with nature.

Popular amenities for Mesopotamia vacation rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia