Vacation rentals in Muscatine

La Casita Guest House

La Casita is a family freindly, fully remodeled 3 bedroom/2 bath home. We are located within a 3 minute drive to historical downtown Muscatine. The kitchen is fully equiped and the home features a king bed, a queen bed and a twin bed for use (a pack-n-play is available if requested). Other features include full tub/shower combos in each bathroom, full size washer & dryer, smoke/carbon monoxide detectors, self check in with keyless entry, wifi, smart TV, and an enclosed private backyard area.

Historic West Hill Retreat

Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Helen's Henhouse

Welcome to the coziness of Helen's Henhouse, a lovingly restored 1890 home. Offering 4 cozy bedrooms, a delightful eat-in kitchen, an extra third-floor twin suite, and a generous living room featuring a dedicated work area, it's designed for retreats but perfect for any escape. Unleash your creativity in our well-equipped workspace, complete with 10 tables, design walls, a cutting station, and an ironing board. Your retreat, your way! A Retreat Haven for Every Stay. Unwind, Create, or Relax.

Shade Tree Farms in Letts, Iowa

Forget your worries in this spacious log home on 30 acres. Perfect for relaxing and renewing. Short drive to Muscatine with many historic sites, shops, unique restaurants. Near Grandview, Wapello, Letts, Columbus Junction with small town features and 35 miles from Iowa City. Mowed walking path around field. Exercise equipment. 2 car garage, 1 motorcycle garage. New pond. Privacy tucked into the field but just off the main highway. Sit and relax on massive front porch and watch the wildlife

Buckman's Guesthouse BnB (5 Bedrooms+)

Enjoy the comfort and welcoming atmosphere of a home built to entertain family & friends. There are 5 guest bedrooms rooms: Room 1-King bed, sofa bed & recliner Room 2-Queen & sofa bed Room 3-Twin beds & convertible sofa Room 4-Queen & sofa bed Room 5-King & recliner Rooms 1,2 &5 have in suite bathrooms. Bathroom for room 4 is next door. Rooms 2 &3 share an inner door; ideal for parents with children. Breakfast is included. To book a room instead of the house, see separate listings.

Hidden Gem In The Quad Cities

Space is the upstairs of a duplex. Self check-in. Safe and friendly neighborhood. This special place is close to everything, making it easy to plan your visit. Note: Access requires steep stairs, so it may not suit guests with mobility concerns. Friendly owners live downstairs and are happy to assist. The place is close to St. Ambrose, Genesis West, Restaurants, 5 min from Palmer, Downtown and Mississippi Valley Fair grounds, 12 min from Augustana and 14 min from the Vibrant Arena.

Waterfront Cabin on Lake Odessa

Take it easy at this unique and tranquil getaway on Lake Odessa in Wapello, Iowa. Enjoy beautiful views and access to fishing, boating, and other natural attractions. This quaint cabin offers plenty of space to relax and enjoy the peace and quiet. Cabin offers two bedrooms with 3 beds and 1 sleeper sofa in the living room. Enjoy two full bathrooms, a half bath and a full kitchen. Cabin is within walking distance of water access, boat ramp, fishing areas and a cute local restaurant

Michelle's Place- The Farm House

Welcome to Michelle's Place- The Farm House. Where it's a farm feel, centrally located in town. It's a completely remodeled home with intentional planning and beautiful design for you to come rest at a home away from home. Close to parks, and walking trials while also only 4 minutes away from the historic downtown area! All aspects inside the home were uniquely picked by the host. With seasonal farm fresh varieties of berries, fruits, and vegetables to be enjoyed in your backyard!

The Emerald Loft Apartment

Stay in a Historic District Downtown loft! River views. Nearby park, playground, bike trails, boat ramps & marina. Shopping, live music, & restaurants. Private entry with 1,000 sqr ft of space, open concept, full kitchen, TV, laundry, private bath, literally right in middle of everything. Check in at Creations by Oz "Jewelry, Wine, & Unique Finds". Enjoy a glass of wine upon check-in. Come hungry. Photo comments provide dining options within steps of the Emerald Room.

Beautiful Condo Downtown with River Views

3rd Floor Condo in the old Hotel Muscatine 100 plus years old just totally refurbished condo with a Beautiful Balcony with view of bridge and Mississippi River 2 bedrooms 1 full bed bedroom and 1 queen bed bedroom with both views of river and bridge and a 1/2 bath bath and full bath with soaking tub and rain shower, stackable washer and dryer, full kitchen fully stocked, desk area, beautiful patio with chairs over looking lit up bridge and river Adults Only 2 Night Minimum

Rock River Escape

Enjoy your coffee, a nice bbq dinner, glass of wine, a good book, or just enjoy the sweeping views out of this cute bungalow. With 180 ft of unobstructed river views and river access, bring your fishing poles and get ready to relax and enjoy watching the water slowly drift by at this centrally located bungalow in a quiet residential neighborhood. Firepit with firewood provided. No parties allowed so please do not inquire about them.

Steps to River • Firepit/Bidet Comfort/Retro Charm

Take Escape to our enchanting two-bedroom treehouse nestled in the heart of the Quad Cities. Perched above the scenic Rock River, this unique retreat offers stunning views that transform with every season. Immerse yourself in nature with easy access to biking trails or spend serene days fishing by the water. Whether you're seeking a peaceful getaway, a luxurious retreat, this cozy haven delivers an unforgettable experience.