Guesthouse vacation rentals in National City

A spacious studio room encompasses a relaxed seating area and a large bed. Natural light enters through multiple windows, and a decorative rug anchors the space. A coffee table sits in the center, and a television is positioned near the seating arrangement.

4.91 out of 5 average rating, 422 reviews

Mid Century Studio Bungalow Near SDSU

This private bungalow sits behind a main house in the beautiful El Cerrito Neighborhood, (College Area). This is a studio type room with a bathroom, bed, and sitting area. There is a private side entrance and plentiful parking. Guests will have full access to the backyard which includes lounging area to enjoy the beautiful San Diego weather. Location is ideally located: 1 mile from SDSU 7 miles from Downtown San Diego 10-15 miles from local beaches 5 miles from North Park All locations are an affordable Uber.

Guesthouse in Mission Hills

A curving staircase is visible, flanked by white walls and adorned with vibrant blue tiles. Handrails provide support along the ascent, leading to a bright upper space. A potted plant enhances the serene ambiance at the top of the stairs.

5 out of 5 average rating, 223 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina. With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

A cozy bedroom is highlighted by a spacious bed adorned with a bright yellow knit blanket. Framed photographs of palm trees and cityscapes decorate the walls, while bedside lamps provide soft illumination on either side of the bed.

4.94 out of 5 average rating, 193 reviews

Clean Cozy Private Guesthouse | Central San Diego

Centrally located, this cozy spot is professionally cleaned, well maintained & managed by a responsive host. Safe & secure it’s close to urban centers yet discretely nestled in a residential neighborhood, within 15 minutes to: The airport Petco Park SD Convention Center the Gas Lamp District SD Zoo Balboa Park Seaport Village beaches, major freeways & much more. Keyless entry for self-check, well-lit entry, generously-sized private, fenced yard, washer/dryer & RO water filter with faucet…

Guesthouse in Spring Valley

An Airstream is positioned on a hillside, surrounded by lush greenery and desert plants. Lounge chairs and a shaded patio area are visible, providing a space for relaxation. The backdrop features rolling hills under a clear sky, highlighting a peaceful and private setting.

4.98 out of 5 average rating, 402 reviews

Views•Sauna•SoakTub•Firepit+Zoo pkg add-on

Nestled in a hillside canyon, a short drive outside the city, this Airstream glamping retreat offers incredible panoramic city, sunset & nature views. Modern comforts include A/C & heat, a full kitchen, fast Wi-Fi, and convenient off-street parking on a gated estate. Cozy up by the firepit as the city sparkles below or try your swing at the golf tee. Reconnect & recharge with your own outdoor hot soaking tub, open-air rain shower, and wood-fired sauna - the perfect retreat for nature lovers!

Superhost

A spacious sleeping area features a queen bed with a patterned throw blanket. Natural light enters through sliding glass doors that lead to the fenced yard. A modern entertainment center displays a flat-screen TV, while a ceiling fan enhances air circulation.

Guesthouse in National City

4.85 out of 5 average rating, 171 reviews

Private Pet-Friendly Studio w/Parking Near Gaslamp

Escape to this cozy, private back-studio, perfect for couples! Located just 4 miles from San Diego’s lively Gaslamp District, this studio offers a peaceful retreat in a safe neighborhood. Enjoy hassle-free parking and a fenced space with a private entrance through the side gate—no face-to-face contact. Fenced yard perfect for pets to play safely, plus nearby dog-friendly beach. Whether you’re here to explore downtown, relax in comfort, or visit Coronado, this studio is your ideal getaway!

Guesthouse in Chula Vista

The bathroom features a modern design with double sinks set within a marble countertop. Two round mirrors reflect the sleek fixtures. A decorative box holds tissues, while a wall-mounted towel rack and a shower curtain can be seen in the background.

4.86 out of 5 average rating, 109 reviews

King Bed Studio in Chula Vista

Prime location in Chula Vista! Less than 2 miles away from the Gaylord Pacific Resort (10 min drive). Just a 20 min drive to most San Diego hot spots. Private studio with very comfortable king bed. Queen air mattress also available in unit. Modern bathroom with double-sink, standing shower, marble tile countertops. Spacious layout, a dedicated workstation and fast wifi. Prep your morning coffee and simple breakfast in the kitchenette. The mini fridge can store your favorite drinks.

An outdoor dining area features a large wooden table set with decorative dishes and neatly folded napkins. An umbrella provides shade above the table. Surrounding greenery and hanging hammocks create a tranquil atmosphere, while a pergola frames the space, enhancing the inviting outdoor setting.

4.96 out of 5 average rating, 388 reviews

Betty- Guesthouse near CBX & San Ysidro border

This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

Guesthouse in National City

An outdoor seating area features a covered gazebo with warm lighting, creating a welcoming ambiance. Surrounding the space are well-maintained grassy areas and neatly arranged stone pathways. Palm trees add a tropical touch against a backdrop of evening clouds and distant city lights.

4.95 out of 5 average rating, 191 reviews

Trendy 1 BR Guesthouse. Great views, no chores.

This is a beautiful 1 bedroom guest house with a Queen size bed and full-size sofa bed. It is close to everything, making it easy to plan your visit. AirPort, Downtown, Coronado, Balboa Park, local beaches, Mexico, and Navy bases are just a few minutes' drive. Private on-site parking. Charge your EV on site. 110v or 220V Don't waste precious time on charging stations. Public transportation as well as plenty of shopping and restaurants within walking distance.

Guesthouse in Normal Heights

A spacious bedroom features a large king size bed with a textured blanket, complemented by a nightstand and a decorative lamp. Sliding glass doors open to a deck, allowing natural light to fill the room. A flat-screen TV and a desk are visible in the background.

4.98 out of 5 average rating, 450 reviews

Mountain View Retreat in Gated Estate (Hot Tub)

Perched above a canyon with spectacular panoramic mountain views, this private guest house is a secluded retreat in one of San Diego’s most eclectic and desirable neighborhoods less than 6 miles from the Downtown San Diego airport. Enjoy a fully equipped kitchen, luxe king size bed and dual sliding glass doors that open to an expansive deck with patio seating, private hot tub and BBQ area.

Guesthouse in National City

A spacious living area features light brown walls and hardwood flooring. A mounted television is displayed on one wall, accompanied by a small coffee table. A dining table with wooden chairs is situated near a window, which is dressed in sheer curtains allowing natural light to filter in.

4.87 out of 5 average rating, 229 reviews

Open concept Guesthouse w/private entrance

Welcome Travelers! We’re thrilled to host fellow Airbnb guests, especially those who love to travel as much as we do. My husband and I have had amazing experiences with Airbnb around the world, and now we're excited to share the beauty of San Diego with you! A few things to note: We live on the property in a completely separate unit with our dog and five chickens.

A spacious studio room features warm wooden walls and contemporary furnishings. A queen-sized bed is accompanied by accent pillows. Large double doors open to a private deck with garden views, while a work desk and chair are positioned near the entrance.

4.9 out of 5 average rating, 1,139 reviews

Safe Hip Quiet GARDEN STUDIO / Northpark

Come to a quiet and stylish studio to relax. Check-in contactless and enjoy! Cozy, hip and private garden studio with private entrance, private full bathroom, and private deck. The Studio house is in a large garden adjoining a craftsman-style house in the historic Northpark/ Morley Field District. Minutes away from coffee shops, breweries, Zoo, Balboa Park.

Guesthouse in Chula Vista

A spacious sleeping area is created with a king bed dressed in neutral linens, complemented by a light bench against the wall. A dresser and closet are present, while a doorway leads to a bathroom area. Natural light filters through a nearby window.

4.86 out of 5 average rating, 183 reviews

#1 Ranked Upgraded Guesthouse w/ Quiet Garden

Experience tranquility in this standalone dwelling unit in San Diego County, perfect for short-term stays. Featuring a king bed, AC, and heat, it offers comfort and convenience. Relax in the quiet garden, watching hummingbirds. Enjoy privacy with the back unit to yourself, complemented by free street parking. A serene retreat in a beautiful setting.

Popular amenities for National City guesthouses

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guesthouses

A private deck is shown, featuring a red umbrella over a round table with four chairs. The entrance to the guest house is framed by glass doors and accompanied by a vibrant red door. Lush greenery and flowerbeds enhance the outdoor space.

4.99 out of 5 average rating, 207 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Superhost

A bright kitchen and living area feature modern decor with a gray couch and teal chairs. The kitchen showcases stainless steel appliances, including a refrigerator and gas stove, while a round dining table invites casual meals. Natural light is provided by nearby windows.

Guesthouse in Talmadge

4.81 out of 5 average rating, 255 reviews

Cozy Casita

Guesthouse in Chula Vista

A clean, modern studio features a spacious bed with light blue and white striped bedding. A kitchenette with a microwave and electric burners is equipped with essential utensils. Large sliding glass doors provide access to a private deck, allowing natural light to fill the room.

4.83 out of 5 average rating, 220 reviews

Private Modern Studio with Ocean View

The living room features a comfortable sectional sofa adorned with decorative cushions. A round coffee table sits in the center, with teal accents adding a pop of color. A dining area with high chairs is visible, along with a wall mirror reflecting light and spaciousness.

4.88 out of 5 average rating, 113 reviews

Casita Daisy: Cozy San Diego 1-bedroom Retreat

A vibrant wall art piece features two alpacas, one with a light-colored fleece and the other with dark fur. They are depicted against a backdrop of green foliage, adding a touch of nature and whimsy to the space.

4.92 out of 5 average rating, 210 reviews

Cosy quiet Guesthouse near SDSU

An open layout studio is presented, featuring a cozy seating area with a grey couch and a rustic wooden coffee table. A dining space with a round table and chairs is visible. The kitchen area, equipped with modern appliances, is complemented by a ceiling fan with decorative light fixtures.

5 out of 5 average rating, 103 reviews

NEW construction - Studio near the Village

A modern kitchen is visible, featuring sleek black cabinets and white countertops. Stainless steel appliances, including a gas stove, are present. A small dining area with a black table and checkered tablecloth complements a cozy seating area, illuminated by natural light from large windows.

4.96 out of 5 average rating, 357 reviews

La Mesa Suite

Guesthouse in Allied Gardens

4.86 out of 5 average rating, 118 reviews

Rose Guest Private Suite. Central location!

Guesthouses with a patio

4.97 out of 5 average rating, 103 reviews

Guesthouse in Bonita

Adorable 1- bedroom guesthouse/Casita

4.99 out of 5 average rating, 229 reviews

A bright bedroom features a spacious bed with white linens, complemented by a cozy sitting area with decorative pillows. Large windows with shutters allow natural light to fill the room, and a small nightstand with a lamp adds functionality. A warm color palette enhances the welcoming atmosphere.

Guesthouse in Talmadge

Adorable cottage in Talmadge

Guesthouse in Sherman Heights

A cozy sleeping area is presented with a spacious bed covered in light linens. Beside it, a nightstand with a lamp provides soft lighting. A small round table with a plant adds a touch of greenery, and natural light enters through bright windows framed by soft curtains.

4.88 out of 5 average rating, 173 reviews

Downtown Cottage Minutes to Gaslamp & Petco Park

Guesthouse in Golden Hill

A charming tiny home exterior is showcased with large, colorful windows set into a vibrant purple frame. Two wooden chairs with green cushions are arranged around a small table, positioned under the shade of a large tree. A welcoming entryway painted in teal is visible.

4.9 out of 5 average rating, 103 reviews

The Under-tree Tiny Home Downtown San Diego

A living area features a cozy orange sofa adorned with colorful pillows. A desk with a green chair is situated near a window covered with vertical blinds, allowing natural light to illuminate the space. An air conditioning unit is mounted on the wall.

4.94 out of 5 average rating, 120 reviews

*KING BED* Colorful Guesthouse by Downtown

The living space is shown with a seating area featuring a dark futon couch paired with decorative cushions. A round coffee table sits on a natural fiber rug. Natural light pours in through expansive glass doors, connecting the indoor area to the outdoor patio.

4.98 out of 5 average rating, 146 reviews

Newly built- North Park Abode w/ patio & roof deck

Guesthouse in City Heights

4.86 out of 5 average rating, 301 reviews

Heart of SD | Zoo Nearby | Private Patio | Central

4.86 out of 5 average rating, 202 reviews

Private Studio with a Panoramic View

Guesthouse rentals with a washer and dryer

Guesthouse in Ocean Beach

A cozy sleeping area features a spacious bed adorned with a textured blanket and decorative pillows. Natural light filters through windows with shutters. A light-colored armchair and circular wooden table complement the inviting ambiance of the room.

4.96 out of 5 average rating, 313 reviews

Private beach guesthouse w/ private parking

The exterior of a renovated guesthouse is presented, featuring a white stucco facade with decorative tiles along the steps. A green door, large windows, and a charming walkway leading to the stairs enhance the inviting appearance of the property.

4.99 out of 5 average rating, 181 reviews

Carrie’s North Park Casita, in Heart of San Diego

Guesthouse in Mission Beach

The living area features natural wood paneling and a warm color palette. Large windows allow ample light, framed by woven shades. A comfortable white sofa and a stylish entertainment unit with a television are visible, along with a decorative chair and a small side table.

4.9 out of 5 average rating, 790 reviews

South Mission Beach Zen-Like Studio

A bright and airy sleeping area is highlighted by a spacious bed with a striped duvet. Built-in shelving lines one wall, displaying books and decorative items. A ceiling fan and large window provide light and airflow, while a TV is mounted on the opposite wall.

4.96 out of 5 average rating, 724 reviews

BEAUTIFUL Private Studio

4.98 out of 5 average rating, 235 reviews

A broad view captures the coastal landscape of La Jolla, featuring the shimmering ocean, serene bay, and city lights under a clear sky. The horizon displays the iconic pier, with the vibrant residential area blended into the backdrop of rolling hills.

Guesthouse in La Jolla

La Jolla Oasis: Ocean, City and Fire Works Views

The bedroom features a upholstered headboard and is accented by warm bedside lamps. A large photograph of a pier over water hangs above the bed, while blue and white decorative pillows add contrasting color. A cozy quilt covers the spacious bed.

4.93 out of 5 average rating, 301 reviews

Enjoy North Park at Comfy & Chic Bungalow Retreat

Guesthouse in Mission Hills

A spacious living area features a large sectional sofa adorned with decorative pillows, complemented by a wooden coffee table. A vibrant wall art piece with colorful surfboards is displayed above the couch, while natural light fills the room through expansive windows.

4.97 out of 5 average rating, 268 reviews

Beautiful Historic Home and Gardens Near Downtown!

A modern living area features a gray pullout sofa adorned with patterned cushions and a small light beside it. A black coffee table rests on a plush area rug, while a dark wood bookshelf displays various books. A striking red cabinet adds color to the room.