Guesthouse vacation rentals in National City

Guesthouse in Mission Hills

5 out of 5 average rating, 194 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina. With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

4.91 out of 5 average rating, 101 reviews

Casita Daisy: Fully Equipped 1BR Home in San Diego

Your Home Away from Home Casita Daisy. Equipped with high speed Wi-Fi, private patio, AC, and Pet-Friendly. Includes a full-equipped kitchen, private bedroom, comfortable living space, and 1-driveway parking. Casita Daisy is centrally located: - 20 mins/ 11 mi. > San Diego Airport & Downtown San Diego - 1 hr > mountains and deserts - 30 mins/15 mi. > Mexico Border - 25 mins/14 mi. > Sea World - 15 mins/8 mi. > San Diego Zoo - 40 mins/35 mi. > San Diego Zoo Safari Park Long term stays welcome.

4.96 out of 5 average rating, 112 reviews

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable

Welcome to our super cozy one bedroom 500 sq. ft. Casita located in the college area of San Diego! You will be tucked away in the corner of our lot with a fully separate entrance and your own private patio. Our unit is equipped with a newly updated kitchen, brand new appliances, a washer & dryer, a and a small workspace in case you need to squeeze in a little work on your vacation. Enjoy easy access to the city as we are less than a 20 min drive to the beach, the airport, downtown, and the zoo!

4.95 out of 5 average rating, 489 reviews

Modern Sweet Home Stay, Hillcrest, A/C Parking W/D

This quaint bungalow sits in a prime location of Hillcrest, a highly desirable area in San Diego. It is very quiet and private and sits directly behind our house(pictured) with a beautifully landscaped brick courtyard. You are within walking distance to "The Heart of Hillcrest" where you will discover many fabulous restaurants, coffee and boutique shops, and so much more. We are a short Uber drive to downtown and everywhere else San Diego has to offer. We hope you stay with us soon!

4.93 out of 5 average rating, 222 reviews

Guesthouse in Encanto

Farm Vibe near City with Friendly Goats & Big Deck

Charming home has spacious bedroom (king bed), full bath (tub/shower), living/dining area and stocked kitchen all with stylish touches. Relax and lounge on your back deck while saying hello to the friendly goats. Your lodging is nearby the city where you can have a touch of countryside as well as modern amenities throughout with keyless entry, WiFi and Smart TV (W/D also available). It's a perfect space for a couple, small family or group of friends looking for a bit of it all next to it all!

Guesthouse in Greater North Park

4.99 out of 5 average rating, 164 reviews

Carrie’s North Park Casita, in Heart of San Diego

Fully renovated stand-alone guesthouse in North Park, consistently voted one of the coolest "hipster" neighborhoods in the US. Just a few blocks from all the action at 30th and University, but tucked away in a quiet, historically designated residential neighborhood. Walk to Balboa Park or The World Famous San Diego Zoo. Get to Downtown San Diego, San Diego International Airport, Old Town, Little Italy, Coronado, La Jolla, Sea World, multiple beaches & so much more in under 15 minutes.

Superhost

Guesthouse in National City

4.85 out of 5 average rating, 156 reviews

Private Pet-Friendly Studio w/Parking Near Gaslamp

Escape to this cozy, private back-studio, perfect for couples! Located just 4 miles from San Diego’s lively Gaslamp District, this studio offers a peaceful retreat in a safe neighborhood. Enjoy hassle-free parking and a fenced space with a private entrance through the side gate—no face-to-face contact. Fenced yard perfect for pets to play safely, plus nearby dog-friendly beach. Whether you’re here to explore downtown, relax in comfort, or visit Coronado, this studio is your ideal getaway!

4.96 out of 5 average rating, 371 reviews

Betty- Guesthouse near CBX & San Ysidro border

This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

Guesthouse in National City

4.95 out of 5 average rating, 173 reviews

Trendy 1 BR Guesthouse. Great views, no chores.

This is a beautiful 1 bedroom guest house with a full-size bed and full-size sofa bed. It is close to everything, making it easy to plan your visit. AirPort, Downtown, Coronado, Balboa Park, local beaches, Mexico, and Navy bases are just a few minutes' drive. Private on-site parking. Charge your EV on site. 110v or 220V Don't waste precious time on charging stations. Public transportation as well as plenty of shopping and restaurants within walking distance.

4.96 out of 5 average rating, 114 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

This is the perfect Guest House with a salted & heated pool & hot tub. We are located in a super quiet & very safe neighborhood in beautiful San Diego, 15 minutes drive to Downtown, La Jolla, Beaches, Zoo, Sea World & Convention Center. Hike next door at Mission Trails & Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo and top quality finishes await you inside. Everything you need for memorable vacation! No smoking or vaping on the property.

Guesthouse in National City

4.86 out of 5 average rating, 214 reviews

Open concept Guesthouse w/private entrance

Welcome Travelers! We’re thrilled to host fellow Airbnb guests, especially those who love to travel as much as we do. My husband and I have had amazing experiences with Airbnb around the world, and now we're excited to share the beauty of San Diego with you! A few things to note: We live on the property in a completely separate unit with our dog and eight chickens, so you'll experience a peaceful, homey environment with a local touch.