Vacation rentals in North Santee River

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Top-rated vacation rentals in North Santee River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favourite
A spacious sleeping area features a king bed with a simple wooden frame and high-quality linens. Two white dogs sit on the floor, with a neon sign hanging above the bed, stating 'the Folly Beach swell and a Charleston lake.' The room is adorned with tropical-themed decor.
Guesthouse in Charleston
4.98 out of 5 average rating, 242 reviews

The James: “Tiny” Home b/w Downtown & Folly

The James is a unique NEW 530 sq ft retro coastal tiny home located in a gorgeous neighborhood on James Island ◡̈ 10 mins to downtown Charleston 12 minutes to Folly Beach Walking distance to restaurants The James sleeps up to 6 people and 2 dogs (NO PET FEE) & boasts a private fenced yard & patio with an outdoor shower and Clawfoot tub! The James is ideal for solo travelers, couples, families, those traveling w/ their dog(s), those w/ limited mobility and groups of friends. #BNB-2023-02

Top guest favourite
Home in Pawleys Island
4.94 out of 5 average rating, 182 reviews

Unique New Remodel Close to Beach and Golf

Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

Top guest favourite
An elegantly decorated sitting area is presented with a detailed mural ceiling and rich purple drapes. A plush loveseat and two accent chairs surround a circular rug in the center. Windows allow natural light to fill the space, highlighting the ornate moldings.
Apartment in North Charleston
4.96 out of 5 average rating, 140 reviews

Bridgerton inspired fantasy 2 min from park circle

Live out your Bridgerton fantasy in this stunning historic space. The apartment features antique furnishings/art, a private entrance and patio with lounge and a hot tub (The hot tub is available Apr through Nov). Off street parking. A sumptuous bathroom with an oversized soaking tub and a kitchenette. There is also a 55 inch frame tv in the bedroom including WiFi. Available for photo shoots upon request rates may differ please contact host prior. Bridal pics by Olivia Allain Permit#2026-0414

Guest favourite
A covered porch features two Adirondack chairs, one painted blue and the other orange, positioned beside a small side table. A view of greenery is visible through a nearby window, contributing to a relaxed outdoor seating area.
Home in Georgetown
4.96 out of 5 average rating, 192 reviews

Carolina Wren Cottage: New, Relaxing, Dog-Friendly

Charming dog friendly cottage located minutes away from historic Georgetown only about an hour from Charleston. Whether you want to sit on the large porch and enjoy listening to the birds sing or watch them fly back and forth through the beautiful trees. Maybe have an adventure walking along the Harbor walk do a little shopping and enjoy the great selection of restaurants. If that wasn't enough there are several beautiful beaches to enjoy. You won't be disappointed. For pets see policies.

Top guest favourite
The exterior of a two-story house is nestled among tall trees, showcasing a deck with steps leading to the ground. Screened-in porches on both levels provide ample outdoor space and views of the surrounding greenery.
Home in Georgetown
4.98 out of 5 average rating, 183 reviews

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Top guest favourite
The living area features a light blue wall, complemented by framed artwork. A bright red loveseat and a dark brown sofa with colorful cushions provide seating. A glass coffee table rests on a textured dark rug, while a wooden cabinet and a television complete the space.
Apartment in Georgetown
4.98 out of 5 average rating, 313 reviews

Georgetown Vogue in the Heart of the City

Located on Front St in the heart of historic Georgetown, this 1 BR, 1 Bath, full kitchen, apartment is located on the second floor of a smartly designed, mixed use, Charleston-style building. Surrounded by restaurants, museums, theater, Harborwalk, and shops, this apartment accommodates 2 in a no smoking environment and offers high speed internet, and large screen TV. No pets. Guests enjoy a quiet setting together with 1 free pass per occupant to the Purr & Pour Cat Café. Free parking.

Superhost
A view of a houseboat docked at a marina, accessible by a wooden walkway. Nearby, a gazebo offers shaded seating. The clear blue sky contrasts with the calm water, while lush greenery lines the distant shore, creating a serene landscape.
Home in Georgetown
4.89 out of 5 average rating, 159 reviews

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Top guest favourite
A charming pathway lined with greenery leads through a white picket gate. The brick-paved path is bordered by flourishing plants and small trees, inviting a serene stroll through the garden-like setting.
Apartment in Charleston
5 out of 5 average rating, 409 reviews

Dream Catcher Carriage House Daniel Island

Our carriage house apartment is located on a peaceful marsh on beautiful Daniel Island next to walking/biking paths. It is also walking distance to parks, shops, and restaurants. Daniel Island is approximately 15 to 20 minutes from the airport, downtown Charleston, and local beaches. All AirBnB rentals in Charleston & Daniel Island must have a business license. The application process was not easy but we did it! Dream Catcher's permit number is OP2018 00373.

Top guest favourite
Guest suite in McClellanville
4.96 out of 5 average rating, 149 reviews

Kit Hall Pool Resort Close to Charleston & Beaches

Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

Top guest favourite
Home in Georgetown
4.98 out of 5 average rating, 161 reviews

Pepe's Place

This charmer is located in the historical district of Georgetown, SC. This home has been updated and should be the perfect place for your stay when visiting. This home is a comfortable and inviting place to spend your time when not exploring the waterfront, great restaurants, or whatever is bringing you to this beautiful historical city. You can also enjoy our closest beach located in Pawley's Island or even take a day trip to Charleston.

Top guest favourite
Home in North Charleston
4.97 out of 5 average rating, 108 reviews

La Petite Fleur Rouge | Elegant & Cozy 2/1 Getaway

🌸 Welcome to La Petite Fleur Rouge in North Charleston, a French-style haven full of rustic elegance and charm! Enjoy soft lavender accents, vintage décor, and handcrafted touches that create a serene, comfortable, and stylish retreat. Designed for a sophisticated and relaxing stay, this French-inspired home brings the allure of Provence together with Southern hospitality for an unforgettable North Charleston getaway.

Guest favourite
A modern living area features a light-colored sectional sofa facing a mounted smart TV, which displays a variety of streaming options. A rustic brick wall serves as a backdrop, while a wooden coffee table and a round dining table with four chairs occupy the space. A ceiling fan and natural light enhance the area's ambiance.
Townhouse in Murrells Inlet
4.95 out of 5 average rating, 224 reviews

Modern 2-bedroom Luxury Home near Inlets Marshwalk

Welcome to the Shady Oak Haven! If your looking for a home away from home, steps away from Inlet's best - you've come to the right place. This 2 bedroom, 2.5 bath beautifully appointed townhome with modern furnishings and luxe amenities is centrally located in the bustling heart of Murrells Inlet. Shady Oak Haven departs from the ordinary coastal rentals, in all the best ways.

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