Vacation rentals in North Santee River

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Top-rated vacation rentals in North Santee River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favourite
Cottage in Mount Pleasant
4.95 out of 5 average rating, 529 reviews

The Boathouse

We call it the Boathouse, but it could just as easily be called the treehouse. It sits just feet from a tidal creek amidst giant live oak trees. A short dock is right outside the door, so bring your kayaks or other small craft. Although cozy, it offers everything a simple cottage should. Shem Creek is minutes away, as are the beaches. Patriot's Point and parks are a short walk away. This is the closest residential neighborhood to Charleston that you will find in Mt Pleasant. ST250324 BL24-000442

Top guest favourite
Home in Pawleys Island
4.94 out of 5 average rating, 182 reviews

Unique New Remodel Close to Beach and Golf

Fully remodeled, the little cabin on the marsh is a 1 BR house with a loft. Inside is almost all wood. The house sits on the marsh water of the Waccamaw river. The neighborhood is a dirt road with a mix of mobile homes and houses. The neighbors are great and have lived on the street for decades. The house is surrounded by live oaks, nature and tidal marsh water in the backyard. Litchfield and Pawleys Island beaches are 5 minutes away. World class golf, restaurants, and grocery stores are near.

Guest favourite
Home in Georgetown
4.96 out of 5 average rating, 192 reviews

Carolina Wren Cottage: New, Relaxing, Dog-Friendly

Charming dog friendly cottage located minutes away from historic Georgetown only about an hour from Charleston. Whether you want to sit on the large porch and enjoy listening to the birds sing or watch them fly back and forth through the beautiful trees. Maybe have an adventure walking along the Harbor walk do a little shopping and enjoy the great selection of restaurants. If that wasn't enough there are several beautiful beaches to enjoy. You won't be disappointed. For pets see policies.

Top guest favourite
Home in Pawleys Island
4.96 out of 5 average rating, 213 reviews

Hardwood Haven Creekhouse

This well built home features just the right mix of modern renovations, wood work, and southern style to include modernized bathrooms, a well equipped kitchen, custom lighting, high ceilings with catwalks, floor to ceiling windows, and so much more. The private 440 foot pier in your back yard includes a covered gazebo. It's great for fishing, crabbing, kayaking or just enjoying the peaceful outdoor retreat! It is a short .8 of a mile to the closest beach access where you can enjoy the ocean.

Top guest favourite
An ornate iron railing features a central palm tree design, surrounded by intricate spirals and floral motifs. The railing overlooks a street lined with historic buildings and greenery, creating a subtle connection to the vibrant atmosphere of the surrounding area.
Apartment in Georgetown
4.98 out of 5 average rating, 365 reviews

Above It All with Southern Style

Located on Front St in the heart of historic Georgetown, this 2 BR/2 BA, full kitchen, 1200 SF apartment with large balcony is located on the 2nd floor of a smartly designed, mixed use, Charleston-style building. Surrounded by restaurants, museums, theater, Harborwalk, and shops, this beautiful apartment accommodates 4, offers high speed WiFi, and a large screen TV. Guests enjoy a quiet setting with 1 free pass per occupant to the Purr & Pour Cat Café. Free parking. No smoking or pets.

Top guest favourite
A wooden deck offers two gray lounge chairs and a table, overlooking a calm river surrounded by lush greenery. Bright clouds drift across the blue sky, enhancing the serene outdoor space. A gazebo and additional seating can be seen in the background.
Home in Georgetown
4.98 out of 5 average rating, 183 reviews

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Superhost
A view of a houseboat docked at a marina, accessible by a wooden walkway. Nearby, a gazebo offers shaded seating. The clear blue sky contrasts with the calm water, while lush greenery lines the distant shore, creating a serene landscape.
Home in Georgetown
4.89 out of 5 average rating, 159 reviews

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Top guest favourite
A modern kitchen is seen with light blue walls and wood flooring. Stainless steel appliances are present, including a stove and refrigerator. A spacious island with three wooden stools stands at the center, while a door leads outside. Natural light filters through the windows.
Home in Charleston
4.89 out of 5 average rating, 203 reviews

Make Yourself at Home

Brick ranch, conveniently located between Downtown Charleston and Folly Beach, 5 minutes to King Street, 20 minutes to Mt. Pleasant and 30 minutes to airport. Full house with 3 bedrooms, 2 bathrooms, open kitchen, dining room and large living room with big screen tv. A screened porch, fenced in backyard, washer & dryer , on site parking for 4 vehicles. Walking distance to 2 playgrounds, tennis court, wildlife sanctuary, state park and a great view of Fort Sumpter and the city.

Top guest favourite
An inviting white church with a steeple is set against a vibrant sunset sky displaying hues of orange, pink, and blue. Surrounding marshlands are lightly visible in the foreground, while a distant road runs parallel to the building.
Apartment in Pawleys Island
4.87 out of 5 average rating, 209 reviews

Osprey's Nest!

'Osprey's Nest' is close to East of Highway 17, 1 mile from the beach. Close to Brookgreen Gardens and Huntington Beach State Park. A few miles from Murrells Inlet, historic Georgetown, and of course Myrtle Beach.. You’ll love my place because of Convenient to attractions, but away from the Myrtle bustle. Excellent local restaurants. Nearby Murrells Inlet is well known for their seafood restaurants. It is a serene and beautiful location. Come unwind with us!.

Top guest favourite
An inviting outdoor space features a uniquely shaped freshwater pool surrounded by a sun patio. Lounge chairs and shaded seating areas are arranged under a gazebo, with lush foliage enhancing the natural setting. The landscaped grounds provide a serene atmosphere for relaxation.
Guest suite in McClellanville
4.96 out of 5 average rating, 148 reviews

Kit Hall Pool Resort Close to Charleston & Beaches

Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba

Top guest favourite
Home in Georgetown
4.98 out of 5 average rating, 161 reviews

Pepe's Place

This charmer is located in the historical district of Georgetown, SC. This home has been updated and should be the perfect place for your stay when visiting. This home is a comfortable and inviting place to spend your time when not exploring the waterfront, great restaurants, or whatever is bringing you to this beautiful historical city. You can also enjoy our closest beach located in Pawley's Island or even take a day trip to Charleston.

Guest favourite
A modern living area features a light-colored sectional sofa facing a mounted smart TV, which displays a variety of streaming options. A rustic brick wall serves as a backdrop, while a wooden coffee table and a round dining table with four chairs occupy the space. A ceiling fan and natural light enhance the area's ambiance.
Townhouse in Murrells Inlet
4.95 out of 5 average rating, 224 reviews

Modern 2-bedroom Luxury Home near Inlets Marshwalk

Welcome to the Shady Oak Haven! If your looking for a home away from home, steps away from Inlet's best - you've come to the right place. This 2 bedroom, 2.5 bath beautifully appointed townhome with modern furnishings and luxe amenities is centrally located in the bustling heart of Murrells Inlet. Shady Oak Haven departs from the ordinary coastal rentals, in all the best ways.

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