Vacation rentals in Panama Canal

4.81 out of 5 average rating, 144 reviews

The Penthouse Annex

Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

4.93 out of 5 average rating, 252 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Superhost

5 out of 5 average rating, 3 reviews

View and Comfort Apartment with Home Warmth

Welcome to your new temporary home in Panama! 🌴 This cozy apartment offers a privileged view of the Cinta Costera, the Pacific Ocean, and the historic Casco Viejo — literally a postcard-perfect scene from your window! 📸 💫 Our space combines the comfort of home with the style of a boutique hotel. Enjoy a cozy, modern, and relaxing stay in a 🔝 location at the heart of the financial district, just steps from restaurants, supermarkets, and iconic landmarks.

Superhost

5 out of 5 average rating, 5 reviews

Yoo Panama - Luxurious and comfortable

Modern, luxurious and unique apartment, which has a spectacular location in one of the most luxurious buildings in Panama City, with all the amenities of a hotel, near supermarkets, pharmacies, restaurants, shopping centers and more The undoubted character, luxury and comfort that this apartment exudes makes it really difficult to leave at the end of your stay. With its enviable ocean view, guests can disconnect, relax and savor this magical destination

4.98 out of 5 average rating, 140 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

4.95 out of 5 average rating, 116 reviews

Luxury apartment in Panama, ocean view

Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

4.93 out of 5 average rating, 124 reviews

Home in Panamá

Exceptional three-story building with sea view

This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

4.96 out of 5 average rating, 46 reviews

New studio apartment in front of the sea

Enjoy by the sea in Panama! Enjoy a full space with kitchen, air conditioning and access to amenities: social area, pool, co-working. The building stands out with an exciting rooftop, bars with a panoramic view. Explore restaurants and additional activities for a unique stay. Your oceanfront escape awaits! Book now and immerse yourself in the serenity and entertainment that only this place can offer.

5 out of 5 average rating, 104 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

4.99 out of 5 average rating, 251 reviews

Condo in Panama

Patty’s Charming Studio with King bed in Casco

Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!

4.99 out of 5 average rating, 100 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA